CD68 Polyclonal Antibody | Bioss bs-0649R product information

product summary

company name :

Bioss

product type :

antibody

product name :

CD68 Polyclonal Antibody

catalog :

bs-0649R

quantity :

100 ul

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

Bioss product webpage

citations: 8

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry - frozen section; mouse	Vendrov A, Stevenson M, Alahari S, Pan H, Wickline S, Madamanchi N, et al. Attenuated Superoxide Dismutase 2 Activity Induces Atherosclerotic Plaque Instability During Aging in Hyperlipidemic Mice. J Am Heart Assoc. 2017;6: pubmed publisher
immunohistochemistry - frozen section; mouse	Kugo H, Zaima N, Onozato M, Miyamoto C, Hashimoto K, Yanagimoto K, et al. Suppressive effects of dietary EPA-rich fish oil on the degradation of elastin fibers in the aortic wall in nicotine-administered mice. Food Funct. 2017;8:2829-2835 pubmed publisher
immunohistochemistry - paraffin section; mouse	Ganguly R, Sahu S, Ohanyan V, Haney R, Chavez R, Shah S, et al. Oral chromium picolinate impedes hyperglycemia-induced atherosclerosis and inhibits proatherogenic protein TSP-1 expression in STZ-induced type 1 diabetic ApoE-/- mice. Sci Rep. 2017;7:45279 pubmed publisher
immunohistochemistry - frozen section; rat; 1:100; loading ...; fig 3 immunohistochemistry; rat	Wang Y, Chen J, Zhou J, Nong F, Lv J, Liu J. Reduced inflammatory cell recruitment and tissue damage in spinal cord injury by acellular spinal cord scaffold seeded with mesenchymal stem cells. Exp Ther Med. 2017;13:203-207 pubmed publisher
immunocytochemistry; mouse	Xu X, Zhang A, Halquist M, Yuan X, Henderson S, Dewey W, et al. Simvastatin promotes NPC1-mediated free cholesterol efflux from lysosomes through CYP7A1/LXRÎ± signalling pathway in oxLDL-loaded macrophages. J Cell Mol Med. 2017;21:364-374 pubmed publisher
immunohistochemistry - paraffin section; human	Kang Y, Kim J, Joung K, Lee J, You B, Choi M, et al. The Roles of Adipokines, Proinflammatory Cytokines, and Adipose Tissue Macrophages in Obesity-Associated Insulin Resistance in Modest Obesity and Early Metabolic Dysfunction. PLoS ONE. 2016;11:e0154003 pubmed publisher
immunohistochemistry - frozen section; mouse	Xu X, Yuan X, Li N, Dewey W, Li P, Zhang F. Lysosomal cholesterol accumulation in macrophages leading to coronary atherosclerosis in CD38(-/-) mice. J Cell Mol Med. 2016;20:1001-13 pubmed publisher
	Chen D, Qi Y, Zhang J, Yang Y. Deconstruction of a hypothalamic astrocyte-white adipocyte sympathetic axis that regulates lipolysis in mice. Nat Commun. 2022;13:7536 pubmed publisher

product information

sku :

bs-0649R

name :

CD68 Polyclonal Antibody

category :

Primary Antibody

conjugation :

Unconjugated

host :

Rabbit

target protein :

CD68

modification :

Unmodified

clonality :

Polyclonal

isotype :

IgG

concentration :

1ug/ul

public immunogen range :

20-70/335

subcellular locations :

Extracellular

source :

KLH conjugated synthetic peptide derived from mouse CD68

gene id link :

Entrez Gene: 12514

swiss prot :

P31996

swiss prot link :

Swiss Prot: P31996

applications :

WB, IHC-P, IF(IHC-P), IF(ICC)

applications with dilutions :

WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200), IF(ICC)(1:50-200)

cross reactive species :

Human, Mouse, Rat

size :

100 ul

background :

Could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. Binds to tissue- and organ-specific lectins or selectins, allowing homing of macrophage subsets to particular sites. Rapid recirculation of CD68 from endosomes and lysosomes to the plasma membrane may allow macrophages to crawl over selectin-bearing substrates or other cells.

purification :

Purified by Protein A.

storage :

Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for 12 months.

synonyms :

Lamp4; gp11; Scard1; Macrosialin; CD68

lead time :

3 to 5 business days.

more info or order :

Bioss product webpage