CD8 Polyclonal Antibody | Bioss bs-0648R product information

product summary

company name :

Bioss

product type :

antibody

product name :

CD8 Polyclonal Antibody

catalog :

bs-0648R

quantity :

100 ul

price :

289.5 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

mouse, rat

application :

western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

Bioss product webpage

citations: 19

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry - paraffin section; mouse; 1:500; loading ...; fig 1d	Pascual García M, Bonfill Teixidor E, Planas Rigol E, Rubio Perez C, Iurlaro R, Arias A, et al. LIF regulates CXCL9 in tumor-associated macrophages and prevents CD8+ T cell tumor-infiltration impairing anti-PD1 therapy. Nat Commun. 2019;10:2416 pubmed publisher
immunohistochemistry - paraffin section; mouse; loading ...; fig 6d	Haikala H, Anttila J, Marques E, Raatikainen T, Ilander M, Hakanen H, et al. Pharmacological reactivation of MYC-dependent apoptosis induces susceptibility to anti-PD-1 immunotherapy. Nat Commun. 2019;10:620 pubmed publisher
immunohistochemistry - paraffin section; mouse	Tanaka R, Goshima F, Esaki S, Sato Y, Murata T, Nishiyama Y, et al. The efficacy of combination therapy with oncolytic herpes simplex virus HF10 and dacarbazine in a mouse melanoma model. Am J Cancer Res. 2017;7:1693-1703 pubmed
immunohistochemistry - paraffin section; mouse	Kroner J, Kovtun A, Kemmler J, Messmann J, Strauss G, Seitz S, et al. Mast Cells Are Critical Regulators of Bone Fracture-Induced Inflammation and Osteoclast Formation and Activity. J Bone Miner Res. 2017;32:2431-2444 pubmed publisher
flow cytometry; mouse	Haffner Luntzer M, Fischer V, Prystaz K, Liedert A, Ignatius A. The inflammatory phase of fracture healing is influenced by oestrogen status in mice. Eur J Med Res. 2017;22:23 pubmed publisher
immunohistochemistry; rat	Willett E, Liu J, Berke M, Giannini P, Schmid M, Jia Z, et al. Standardized Rat Model Testing Effects of Inflammation and Grafting on Extraction Healing. J Periodontol. 2017;88:799-807 pubmed publisher
immunohistochemistry - paraffin section; mouse	Chuang M, Jan M, Chang J, Lu F. The Chinese medicine JC-001 enhances the chemosensitivity of Lewis lung tumors to cisplatin by modulating the immune response. BMC Complement Altern Med. 2017;17:210 pubmed publisher
immunohistochemistry; mouse	Wang R, Johnson T, He J, Rong Z, Wong M, Nigam V, et al. Humanized mouse model for assessing the human immune response to xenogeneic and allogeneic decellularized biomaterials. Biomaterials. 2017;129:98-110 pubmed publisher
immunohistochemistry - paraffin section; mouse	Ju H, Xing W, Yang J, Zheng Y, Jia X, Zhang B, et al. An effective cytokine adjuvant vaccine induces autologous T-cell response against colon cancer in an animal model. BMC Immunol. 2016;17:31 pubmed
immunohistochemistry - paraffin section; mouse	Li Y, Kobayashi K, Mona M, Satomi C, Okano S, Inoue H, et al. Immunogenic FEAT protein circulates in the bloodstream of cancer patients. J Transl Med. 2016;14:275 pubmed
immunohistochemistry - paraffin section; mouse	Kovtun A, Bergdolt S, Wiegner R, Radermacher P, Huber Lang M, Ignatius A. The crucial role of neutrophil granulocytes in bone fracture healing. Eur Cell Mater. 2016;32:152-62 pubmed
immunohistochemistry - paraffin section; mouse; fig 6	Ashraf M, Schwelberger H, Brendel K, Feurle J, Andrassy J, Kotsch K, et al. Exogenous Lipocalin 2 Ameliorates Acute Rejection in a Mouse Model of Renal Transplantation. Am J Transplant. 2016;16:808-20 pubmed publisher
western blot; mouse	Jeong K, Lee E, Yang S, Seong J. Combination of macrophage inflammatory protein 1 alpha with existing therapies to enhance the antitumor effects on murine hepatoma. J Radiat Res. 2015;56:37-45 pubmed publisher
immunohistochemistry - paraffin section; mouse	Lee M, Yang K, Wang N, Chiu Y, Chen P, Chen Y. The development of a murine model for Forcipomyia taiwana (biting midge) allergy. PLoS ONE. 2014;9:e91871 pubmed publisher
immunohistochemistry - frozen section; rat	Qiao X, Jiang K, Nie J, Fan K, Zheng Z, Wang J, et al. Increased expression of Tim-3 and its ligand Galectin-9 in rat allografts during acute rejection episodes. Biochem Biophys Res Commun. 2014;445:542-8 pubmed publisher
immunohistochemistry - paraffin section; mouse	Zhang W, Fei Y, Gao J, Liu B, Zhang F. The role of CXCR3 in the induction of primary biliary cirrhosis. Clin Dev Immunol. 2011;2011:564062 pubmed publisher
immunohistochemistry - paraffin section; mouse	He Q, Li J, Yin W, Song Z, Zhang Z, Yi T, et al. Low-dose paclitaxel enhances the anti-tumor efficacy of GM-CSF surface-modified whole-tumor-cell vaccine in mouse model of prostate cancer. Cancer Immunol Immunother. 2011;60:715-30 pubmed publisher
	Haffner Luntzer M, Foertsch S, Fischer V, Prystaz K, Tschaffon M, Mödinger Y, et al. Chronic psychosocial stress compromises the immune response and endochondral ossification during bone fracture healing via β-AR signaling. Proc Natl Acad Sci U S A. 2019;116:8615-8622 pubmed publisher
	Liao W, Overman M, Boutin A, Shang X, Zhao D, Dey P, et al. KRAS-IRF2 Axis Drives Immune Suppression and Immune Therapy Resistance in Colorectal Cancer. Cancer Cell. 2019;35:559-572.e7 pubmed publisher

product information

sku :

bs-0648R

name :

CD8 Polyclonal Antibody

category :

Primary Antibody

conjugation :

Unconjugated

host :

Rabbit

target protein :

CD8

modification :

Unmodified

clonality :

Polyclonal

isotype :

IgG

concentration :

1ug/ul

public immunogen range :

50-90/247

subcellular locations :

Extracellular

source :

KLH conjugated synthetic peptide derived from mouse CD8

gene id link :

Entrez Gene: 12525

swiss prot :

P01731

swiss prot link :

Swiss Prot: P01731

applications :

WB, IHC-P, IF(IHC-P)

applications with dilutions :

WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)

cross reactive species :

Mouse, Rat

size :

100 ul

price :

289.5 USD

background :

Identifies cytotoxic/suppressor T-cells that interact with MHC class I bearing targets. CD8 is thought to play a role in the process of T-cell mediated killing. CD8 alpha chains binds to class I MHC molecules alpha-3 domains.

purification :

Purified by Protein A.

storage :

Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for 12 months.

synonyms :

Ly-2; Ly-B; Ly-35; Lyt-2; BB154331; T-cell surface glycoprotein CD8 alpha chain; T-cell surface glycoprotein Lyt-2; CD8a; Lyt2

lead time :

3 to 5 business days.

more info or order :

Bioss product webpage