P38 MAPK Polyclonal Antibody | Bioss bs-0637R product information

product summary

company name :

Bioss

product type :

antibody

product name :

P38 MAPK Polyclonal Antibody

catalog :

bs-0637R

quantity :

100 ul

price :

289.5 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunocytochemistry, immunohistochemistry - paraffin section

more info or order :

Bioss product webpage

citations: 13

Published Application/Species/Sample/Dilution	Reference
western blot; rat	Zhao H, Xue Y, Guo Y, Sun Y, Liu D, Wang X. Inhibition of endocan attenuates monocrotaline-induced connective tissue disease related pulmonary arterial hypertension. Int Immunopharmacol. 2017;42:115-121 pubmed publisher
western blot; rat	Liu X, Zhang J, Han W, Wang Y, Liu Y, Zhang Y, et al. Inhibition of BTK protects lungs from trauma-hemorrhagic shock-induced injury in rats. Mol Med Rep. 2017;16:192-200 pubmed publisher
western blot; rat	Ning C, Wang X, Gao S, Mu J, Wang Y, Liu S, et al. Chicory inulin ameliorates type 2 diabetes mellitus and suppresses JNK and MAPK pathways in vivo and in vitro. Mol Nutr Food Res. 2017;: pubmed publisher
western blot; human	Li M, Cheng W, Nie T, Lai H, Hu X, Luo J, et al. Selenoprotein K Mediates the Proliferation, Migration, and Invasion of Human Choriocarcinoma Cells by Negatively Regulating Human Chorionic Gonadotropin Expression via ERK, p38 MAPK, and Akt Signaling Pathway. Biol Trace Elem Res. 2017;: pubmed publisher
western blot; mouse	Shi Z, Zhan Y, Zhao J, Wang J, Ma H. Effects of Fluoride on the Expression of p38MAPK Signaling Pathway-Related Genes and Proteins in Spleen Lymphocytes of Mice. Biol Trace Elem Res. 2016;173:333-8 pubmed publisher
western blot; rat	Zhao H, Liu Z, Liu W, Han X, Zhao M. Betulin attenuates lung and liver injuries in sepsis. Int Immunopharmacol. 2016;30:50-6 pubmed publisher
immunohistochemistry - paraffin section; mouse	Cai J, He B, Li X, Sun M, Lam A, Qiao B, et al. Regulation of tumorigenesis in oral epithelial cells by defined reprogramming factors Oct4 and Sox2. Oncol Rep. 2016;36:651-8 pubmed publisher
western blot; rat	Cong L, Chen W. Neuroprotective Effect of Ginsenoside Rd in Spinal Cord Injury Rats. Basic Clin Pharmacol Toxicol. 2016;119:193-201 pubmed publisher
immunohistochemistry - paraffin section; mouse; 1:800; fig 5c	Zhang J, Jing X, Niu W, Zhang M, Ge L, Miao C, et al. Peroxiredoxin 1 has an anti-apoptotic role via apoptosis signal-regulating kinase 1 and p38 activation in mouse models with oral precancerous lesions. Oncol Lett. 2016;12:413-420 pubmed
immunohistochemistry - paraffin section; rat	Zhang N, Zang X, Dong N, Liu F, Wang S, Yan H, et al. Effect of vasopressin on hippocampal injury in a rodent model of asphyxial cardiopulmonary arrest. Exp Ther Med. 2016;11:1385-1392 pubmed
western blot; rat; 1:500; fig 5	Yu H, Shi L, Qi G, Zhao S, Gao Y, Li Y. Gypenoside Protects Cardiomyocytes against Ischemia-Reperfusion Injury via the Inhibition of Mitogen-Activated Protein Kinase Mediated Nuclear Factor Kappa B Pathway In Vitro and In Vivo. Front Pharmacol. 2016;7:148 pubmed publisher
western blot; human	Li L, Dong H, Song E, Xu X, Liu L, Song Y. Nrf2/ARE pathway activation, HO-1 and NQO1 induction by polychlorinated biphenyl quinone is associated with reactive oxygen species and PI3K/AKT signaling. Chem Biol Interact. 2014;209:56-67 pubmed publisher
western blot; rat	Wang B, Zhu Q, Man X, Guo L, Hao L. Ginsenoside Rd inhibits apoptosis following spinal cord ischemia/reperfusion injury. Neural Regen Res. 2014;9:1678-87 pubmed publisher

product information

sku :

bs-0637R

name :

P38 MAPK Polyclonal Antibody

category :

Primary Antibody

conjugation :

Unconjugated

host :

Rabbit

target protein :

P38 MAPK

modification :

Unmodified

clonality :

Polyclonal

isotype :

IgG

concentration :

1ug/ul

public immunogen range :

160-210/360

subcellular locations :

Cytoplasm, Nucleus

source :

KLH conjugated synthetic peptide derived from human P38MAPK

gene id link :

Entrez Gene: 1432

swiss prot :

Q16539

swiss prot link :

Swiss Prot: Q16539

applications :

WB, IHC-P, IF(IHC-P), IF(ICC)

applications with dilutions :

WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200), IF(ICC)(1:50-200)

cross reactive species :

Human, Mouse, Rat

size :

100 ul

price :

289.5 USD

background :

The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response. Four alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]

purification :

Purified by Protein A.

storage :

Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for 12 months.

synonyms :

RK; p38; CSBP; EXIP; Mxi2; CSBP1; CSBP2; CSPB1; PRKM14; PRKM15; SAPK2A; p38ALPHA; Mitogen-activated protein kinase 14; MAP kinase 14; MAPK 14; Cytokine suppressive anti-inflammatory drug-binding protein; CSAID-binding protein; MAP kinase MXI2; MAX-interacting protein 2; Mitogen-activated protein kinase p38 alpha; MAP kinase p38 alpha; Stress-activated protein kinase 2a; MAPK14

lead time :

3 to 5 business days.

more info or order :

Bioss product webpage