product summary
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company name :
Bioss
product type :
antibody
product name :
Pro-Collagen 1 Polyclonal Antibody
catalog :
bs-0578R
quantity :
100 ul
price :
289.5 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat, dog, rabbit
application :
western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section
more info or order :
citations: 14
Published Application/Species/Sample/DilutionReference
  • western blot; dog
Yu C, Liu Y, Sun L, Wang D, Wang Y, Zhao S, et al. Chronic obstructive sleep apnea promotes aortic remodeling in canines through miR-145/Smad3 signaling pathway. Oncotarget. 2017;8:37705-37716 pubmed publisher
  • immunohistochemistry - paraffin section; rat
Tian F, Li S, Yang K, Luo Y, Dai M, Liu G, et al. Orally administered simvastatin partially preserves lumbar vertebral bone mass but not integrity of intervertebral discs in ovariectomized rats. Exp Ther Med. 2017;13:877-884 pubmed publisher
  • western blot; rat
Yang N, Shi J, Wu F, Li M, Zhang X, Li Y, et al. Caffeic acid phenethyl ester up-regulates antioxidant levels in hepatic stellate cell line T6 via an Nrf2-mediated mitogen activated protein kinases pathway.. World J Gastroenterol. 2017;23:1203-1214 pubmed publisher
  • immunohistochemistry - paraffin section; rabbit; fig 7
Ren X, Wang F, Chen C, Gong X, Yin L, Yang L. Engineering zonal cartilage through bioprinting collagen type II hydrogel constructs with biomimetic chondrocyte density gradient. BMC Musculoskelet Disord. 2016;17:301 pubmed publisher
  • immunohistochemistry - paraffin section; rabbit
Wang C, Yang K, Lin K, Liu Y, Yang Y, Kuo T, et al. Expandable Scaffold Improves Integration of Tissue-Engineered Cartilage: An In Vivo Study in a Rabbit Model. Tissue Eng Part A. 2016;22:873-84 pubmed publisher
  • immunohistochemistry; human
Cecen B, Kozaci L, Yuksel M, Ustun O, Ergur B, Havitcioglu H. Biocompatibility and biomechanical characteristics of loofah based scaffolds combined with hydroxyapatite, cellulose, poly-l-lactic acid with chondrocyte-like cells. Mater Sci Eng C Mater Biol Appl. 2016;69:437-46 pubmed publisher
  • immunohistochemistry - paraffin section; rat
Çakır-Özkan N, Bereket C, Sener I, Alici O, Kabak Y, Onger M. Therapeutic Effects of Sildenafil on Experimental Mandibular Fractures. J Craniofac Surg. 2016;27:615-20 pubmed publisher
  • immunohistochemistry - paraffin section; mouse
Xu Z, Chen Y, Huang A, Varghese Z, Moorhead J, Yan F, et al. Inflammatory stress exacerbates lipid-mediated renal injury in ApoE/CD36/SRA triple knockout mice. Am J Physiol Renal Physiol. 2011;301:F713-22 pubmed publisher
  • immunohistochemistry - paraffin section; rat
Luo Y, Zhang L, Wang W, Hu Q, Song H, Su Y, et al. Alendronate retards the progression of lumbar intervertebral disc degeneration in ovariectomized rats. Bone. 2013;55:439-48 pubmed publisher
  • immunohistochemistry - paraffin section; rat
Zhou N, Wang T, Song J, He H, He J, He L. Antihypertensive and vascular remodelling effects of the imperatorin derivative OW1 in renovascular hypertension rats. Clin Exp Pharmacol Physiol. 2014;41:571-8 pubmed publisher
  • western blot; mouse
GUO H, Li Z, Dong S, Chen W, Deng L, Wang Y, et al. Piezoelectric PU/PVDF electrospun scaffolds for wound healing applications. Colloids Surf B Biointerfaces. 2012;96:29-36 pubmed publisher
  • immunohistochemistry - paraffin section; rabbit
McNary S, Athanasiou K, Reddi A. Transforming growth factor β-induced superficial zone protein accumulation in the surface zone of articular cartilage is dependent on the cytoskeleton. Tissue Eng Part A. 2014;20:921-9 pubmed publisher
Yang F, Yang D, Tu J, Zheng Q, Cai L, Wang L. Strontium enhances osteogenic differentiation of mesenchymal stem cells and in vivo bone formation by activating Wnt/catenin signaling. Stem Cells. 2011;29:981-91 pubmed publisher
Zhang Q, Ma S, Xi D, Zhang W, Li A. Administration of a novel penicillamine-bound membrane: a preventive and therapeutic treatment for abdominal adhesions. BMC Surg. 2011;11:5 pubmed publisher
product information
sku :
bs-0578R
name :
Pro-Collagen 1 Polyclonal Antibody
category :
Primary Antibody
conjugation :
Unconjugated
host :
Rabbit
target protein :
Collagen 1
specificity :
This antibody is produced using a peptide that is found in the C-terminal propeptide region.
modification :
Unmodified
clonality :
Polyclonal
isotype :
IgG
concentration :
1ug/ul
public immunogen range :
1350-1400/1464
subcellular locations :
Extracellular
source :
KLH conjugated synthetic peptide derived from human Collagen I
gene id link :
Entrez Gene: 1277
applications :
IHC-P, IF(IHC-P)
applications with dilutions :
IHC-P(1:100-500), IF(IHC-P)(1:50-200)
cross reactive species :
Human, Mouse, Rat
size :
100 ul
price :
289.5 USD
background :
This gene encodes the pro-alpha1 chains of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIA, Ehlers-Danlos syndrome Classical type, Caffey Disease and idiopathic osteoporosis. Reciprocal translocations between chromosomes 17 and 22, where this gene and the gene for platelet-derived growth factor beta are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans, resulting from unregulated expression of the growth factor. Two transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene. [provided by R. Dalgleish, Feb 2008].
purification :
Purified by Protein A.
storage :
Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for 12 months.
synonyms :
Collagen alpha-1(I) chain; Alpha-1 type I collagen; COL1A1, Pro-collagen 1.
lead time :
3 to 5 business days.
more info or order :
company information
Bioss
500 West Cummings Park
Suite 6500
Woburn, MA 01801
info@biossusa.com
biossusa.com
800-501-7654
headquarters: USA
Bioss Inc is a leading antibody developer and manufacturer with state of the art technologies. We have developed over 11,000 antigens/primary antibodies and more than 130,000 derived products including fluorochrome conjugated antibodies. In addition to reliable loading control and tag antibodies, our catalog includes over 1000 specific antibodies recognizing proteins with phosphorylation, acetylation, or methylation modifications. Our company promises fast delivery with strong, top quality scientific support. Bioss Inc is located in the greater Boston area of Massachusetts, the center of the world's largest and fastest growing biotech community.