Integrin beta 1 Polyclonal Antibody | Bioss bs-0486R product information

product summary

company name :

Bioss

product type :

antibody

product name :

Integrin beta 1 Polyclonal Antibody

catalog :

bs-0486R

quantity :

100 ul

price :

289.5 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat, rabbit

application :

western blot, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section, other

more info or order :

Bioss product webpage

citations: 10

Published Application/Species/Sample/Dilution	Reference
western blot; human	Zhao X, Yu D, Yang J, Xue K, Liu Y, Jin C. Knockdown of Snail inhibits epithelial-mesenchymal transition of human laryngeal squamous cell carcinoma Hep-2 cells through the vitamin D receptor signaling pathway. Biochem Cell Biol. 2017;:1-7 pubmed publisher
flow cytometry; human	Zhan F, Liu X, Wang X. The Role of MicroRNA-143-5p in the Differentiation of Dental Pulp Stem Cells into Odontoblasts by Targeting Runx2 via the OPG/RANKL Signaling Pathway. J Cell Biochem. 2017;: pubmed publisher
western blot; rat	Qin J, Wang L, Zheng L, Zhou X, Zhang Y, Yang T, et al. Concentrated growth factor promotes Schwann cell migration partly through the integrin β1-mediated activation of the focal adhesion kinase pathway. Int J Mol Med. 2016;37:1363-70 pubmed publisher
flow cytometry; rabbit	Wang Y, Huang X, Tang Y, Lin H, Zhou N. Effects of panax notoginseng saponins on the osteogenic differentiation of rabbit bone mesenchymal stem cells through TGF-β1 signaling pathway. BMC Complement Altern Med. 2016;16:319 pubmed publisher
immunohistochemistry - paraffin section; mouse	Fu M, Song Y, Wen Z, Lu X, Cui L. Inositol Hexaphosphate and Inositol Inhibit Colorectal Cancer Metastasis to the Liver in BALB/c Mice. Nutrients. 2016;8: pubmed publisher
western blot; mouse	Oralová V, Matalova E, Killinger M, Knopfova L, Smarda J, Buchtová M. Osteogenic Potential of the Transcription Factor c-MYB. Calcif Tissue Int. 2016;: pubmed publisher
other; rat	Deng W, Chen Q, Li X, Yuan Z, Li G, Ke D, et al. Bone marrow mesenchymal stromal cells with CD47 high expression via the signal transducer and activators of transcription signaling pathway preventing myocardial fibrosis. Int J Clin Exp Pathol. 2015;8:10555-64 pubmed
western blot; rat	Chen X, Shi Y, Shu B, Xie X, Yang R, Zhang L, et al. The effect of porcine ADM to improve the burn wound healing. Int J Clin Exp Pathol. 2013;6:2280-91 pubmed
immunohistochemistry - paraffin section; mouse	Lei M, Guo H, Qiu W, Lai X, Yang T, Widelitz R, et al. Modulating hair follicle size with Wnt10b/DKK1 during hair regeneration. Exp Dermatol. 2014;23:407-13 pubmed publisher
	Jiang X, Wang J, Zhang K, Tang S, Ren C, Chen Y. The role of CD29-ILK-Akt signaling-mediated epithelial-mesenchymal transition of liver epithelial cells and chemoresistance and radioresistance in hepatocellular carcinoma cells. Med Oncol. 2015;32:141 pubmed publisher

product information

sku :

bs-0486R

name :

Integrin beta 1 Polyclonal Antibody

category :

Primary Antibody

conjugation :

Unconjugated

host :

Rabbit

target protein :

Integrin beta 1

modification :

Unmodified

clonality :

Polyclonal

isotype :

IgG

concentration :

1ug/ul

public immunogen range :

10-60/798

subcellular locations :

Extracellular

source :

KLH conjugated synthetic peptide derived from human Integrin beta 1

gene id link :

Entrez Gene: 3688

swiss prot :

P05556

swiss prot link :

Swiss Prot: P05556

applications :

WB, IHC-P, IF(IHC-P), IF(ICC)

applications with dilutions :

WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200), IF(ICC)(1:50-200)

cross reactive species :

Human, Mouse, Rat

size :

100 ul

price :

289.5 USD

background :

Integrins alpha-1/beta-1, alpha-2/beta-1, alpha-10/beta-1 and alpha-11/beta-1 are receptors for collagen. Integrins alpha-1/beta-1 and alpha-2/beta-2 recognize the proline-hydroxylated sequence G-F-P-G-E-R in collagen. Integrins alpha-2/beta-1, alpha-3/beta-1, alpha-4/beta-1, alpha-5/beta-1, alpha-8/beta-1, alpha-10/beta-1, alpha-11/beta-1 and alpha-V/beta-1 are receptors for fibronectin. Alpha-4/beta-1 recognizes one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. Integrin alpha-5/beta-1 is a receptor for fibrinogen. Integrin alpha-1/beta-1, alpha-2/beta-1, alpha-6/beta-1 and alpha-7/beta-1 are receptors for lamimin. Integrin alpha-4/beta-1 is a receptor for VCAM1. It recognizes the sequence Q-I-D-S in VCAM1. Integrin alpha-9/beta-1 is a receptor for VCAM1, cytotactin and osteopontin. It recognizes the sequence A-E-I-D-G-I-E-L in cytotactin. Integrin alpha-3/beta-1 is a receptor for epiligrin, thrombospondin and CSPG4. Alpha-3/beta-1 may mediate with LGALS3 the stimulation by CSPG4 of endothelial cells migration. Integrin alpha-V/beta-1 is a receptor for vitronectin. Beta-1 integrins recognize the sequence R-G-D in a wide array of ligands. Isoform beta-1B interferes with isoform beta-1A resulting in a dominant negative effect on cell adhesion and migration (in vitro). In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions.

purification :

Purified by Protein A.

storage :

Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for 12 months.

synonyms :

CD29; FNRB; MDF2; VLAB; GPIIA; MSK12; VLA-BETA; Integrin beta-1; Fibronectin receptor subunit beta; Glycoprotein IIa; VLA-4 subunit beta; ITGB1

lead time :

3 to 5 business days.

more info or order :

Bioss product webpage