GAPDH Polyclonal Antibody | Bioss bs-0459R product information

product summary

company name :

Bioss

product type :

antibody

product name :

GAPDH Polyclonal Antibody

catalog :

bs-0459R

quantity :

100 ul

price :

289.5 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunocytochemistry, immunohistochemistry - paraffin section

more info or order :

Bioss product webpage

citations: 4

Published Application/Species/Sample/Dilution	Reference
western blot; human; 1:1000; fig 4	Zhang J, Hu Q, Guo F, Wang L, Zhao W, Zhang D, et al. Screening and identification of post-traumatic stress-related serum factors in children with Wilms' tumors. Oncol Lett. 2016;11:1299-1304 pubmed
western blot; human	Zenón F, Cantres-Rosario Y, Adiga R, Gonzalez M, Rodriguez-Franco E, Langford D, et al. HIV-infected microglia mediate cathepsin B-induced neurotoxicity. J Neurovirol. 2015;21:544-58 pubmed publisher
western blot; mouse	Wang W, Ju X, Sun Z, Hou W, Yang L, Zhang R. Overexpression of heparan sulfate 6-O-sulfotransferase-2 enhances fibroblast growth factor-mediated chondrocyte growth and differentiation. Int J Mol Med. 2015;36:825-32 pubmed publisher
western blot; human	Shou Z, Lin L, Liang J, Li J, Chen H. Expression and prognosis of FOXO3a and HIF-1α in nasopharyngeal carcinoma. J Cancer Res Clin Oncol. 2012;138:585-93 pubmed publisher

product information

sku :

bs-0459R

name :

GAPDH Polyclonal Antibody

category :

Primary Antibody

conjugation :

Unconjugated

host :

Rabbit

target protein :

GAPDH

modification :

Unmodified

clonality :

Polyclonal

isotype :

IgG

concentration :

1ug/ul

public immunogen range :

90-140/333

subcellular locations :

Cytoplasm

source :

KLH conjugated synthetic peptide derived from mouse GAPDH

gene id link :

Entrez Gene: 14433

swiss prot :

P16858

swiss prot link :

Swiss Prot: P16858

applications :

WB, IHC-P, IF(IHC-P)

applications with dilutions :

WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)

cross reactive species :

Human, Mouse, Rat

size :

100 ul

price :

289.5 USD

background :

Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Modulates the organization and assembly of the cytoskeleton. Facilitates the CHP1-dependent microtubule and membrane associations through its ability to stimulate the binding of CHP1 to microtubules. Also participates in nuclear events including transcription, RNA transport, DNA replication and apoptosis. Nuclear functions are probably due to the nitrosylase activity that mediates cysteine S-nitrosylation of nuclear target proteins such as SIRT1, HDAC2 and PRKDC. Component of the GAIT (gamma interferon-activated inhibitor of translation) complex which mediates interferon-gamma-induced transcript-selective translation inhibition in inflammation processes. Upon interferon-gamma treatment assembles into the GAIT complex which binds to stem loop-containing GAIT elements in the 3'-UTR of diverse inflammatory mRNAs (such as ceruplasmin) and suppresses their translation.

purification :

Purified by Protein A.

storage :

Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for 12 months.

synonyms :

Gapd; Glyceraldehyde-3-phosphate dehydrogenase; GAPDH; Peptidyl-cysteine S-nitrosylase GAPDH

lead time :

3 to 5 business days.

more info or order :

Bioss product webpage