Factor 8 Polyclonal Antibody | Bioss bs-0434R product information

product summary

company name :

Bioss

product type :

antibody

product name :

Factor 8 Polyclonal Antibody

catalog :

bs-0434R

quantity :

100 ul

price :

289.5 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat, rabbit

application :

immunocytochemistry, immunohistochemistry - paraffin section

more info or order :

Bioss product webpage

citations: 3

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry - paraffin section; rabbit	Song J, Li Z, Yu A. Effects of preserving different veins on flow-through flap survival: An experimental study. Exp Ther Med. 2016;11:318-324 pubmed
immunocytochemistry; human	Lei J, Peng S, Samuel S, Zhang S, Wu Y, Wang P, et al. A simple and biosafe method for isolation of human umbilical vein endothelial cells. Anal Biochem. 2016;508:15-8 pubmed publisher
immunohistochemistry - paraffin section; rat	Yu J, Zhang X, Jiang W, Wang H, Zhang Y. Astragalosides promote angiogenesis via vascular endothelial growth factor and basic fibroblast growth factor in a rat model of myocardial infarction. Mol Med Rep. 2015;12:6718-26 pubmed publisher

product information

sku :

bs-0434R

name :

Factor 8 Polyclonal Antibody

category :

Primary Antibody

conjugation :

Unconjugated

host :

Rabbit

target protein :

Factor 8

modification :

Unmodified

clonality :

Polyclonal

isotype :

IgG

concentration :

1ug/ul

public immunogen range :

420-470/2258

source :

KLH conjugated synthetic peptide derived from rat factor VIII

gene id link :

Entrez Gene: 302470

swiss prot :

Q7TN96

swiss prot link :

Swiss Prot: Q7TN96

applications :

IHC-P, IF(IHC-P)

applications with dilutions :

IHC-P(1:100-500), IF(IHC-P)(1:50-200)

cross reactive species :

Human, Mouse, Rat

size :

100 ul

price :

289.5 USD

background :

This gene encodes coagulation factor VIII, which participates in the intrinsic pathway of blood coagulation; factor VIII is a cofactor for factor IXa which, in the presence of Ca+2 and phospholipids, converts factor X to the activated form Xa. This gene produces two alternatively spliced transcripts. Transcript variant 1 encodes a large glycoprotein, isoform a, which circulates in plasma and associates with von Willebrand factor in a noncovalent complex. This protein undergoes multiple cleavage events. Transcript variant 2 encodes a putative small protein, isoform b, which consists primarily of the phospholipid binding domain of factor VIIIc. This binding domain is essential for coagulant activity. Defects in this gene results in hemophilia A, a common recessive X-linked coagulation disorder. [provided by RefSeq, Jul 2008].

purification :

Purified by Protein A.

storage :

Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for 12 months.

synonyms :

coagulation factor VIII; Ahf; Antihemophilic factor; Coagulation factor VIII; Coagulation factor VIII procoagulent component; Coagulation factor VIIIc; Dna segment on chromosome x unique 1253 expressed sequence; Dxs1253e; F8; F8 protein;F8c; FactorVIII; FVIII; Hema coagulation factor VIIIc procoagulent component; Hemophilia a; Hemophilia classic;

lead time :

3 to 5 business days.

more info or order :

Bioss product webpage