OPG Polyclonal Antibody | Bioss bs-0431R product information

product summary

company name :

Bioss

product type :

antibody

product name :

OPG Polyclonal Antibody

catalog :

bs-0431R

quantity :

100 ul

price :

289.5 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunocytochemistry, immunohistochemistry - paraffin section

more info or order :

Bioss product webpage

citations: 11

Published Application/Species/Sample/Dilution	Reference
western blot; human	Zhan F, Liu X, Wang X. The Role of MicroRNA-143-5p in the Differentiation of Dental Pulp Stem Cells into Odontoblasts by Targeting Runx2 via the OPG/RANKL Signaling Pathway. J Cell Biochem. 2018;119:536-546 pubmed publisher
western blot; rat	Yu X, Gong Z, Lin Q, Wang W, Liu S, Li S. Denervation effectively aggravates rat experimental periodontitis. J Periodontal Res. 2017;52:1011-1020 pubmed publisher
western blot; rat	Xiao W, Hu Z, Li T, Li J. Bone fracture healing is delayed in splenectomic rats. Life Sci. 2017;173:55-61 pubmed publisher
western blot; rat	Zhang X, Chen K, Wei B, Liu X, Lei Z, Bai X. Ginsenosides Rg3 attenuates glucocorticoid-induced osteoporosis through regulating BMP-2/BMPR1A/Runx2 signaling pathway. Chem Biol Interact. 2016;256:188-97 pubmed publisher
western blot; rat; 1:500; fig 5	Chen Z, Xue J, Shen T, Mu S, Fu Q. Curcumin alleviates glucocorticoid-induced osteoporosis through the regulation of the Wnt signaling pathway. Int J Mol Med. 2016;37:329-38 pubmed publisher
western blot; mouse	Herath S, Lion T, Klein M, Stenger D, Scheuer C, Holstein J, et al. Stimulation of angiogenesis by cilostazol accelerates fracture healing in mice. J Orthop Res. 2015;33:1880-7 pubmed publisher
immunohistochemistry - paraffin section; rat	Li X, Wu X, Ma Y, Hao Z, Chen S, Fu T, et al. Oral administration of 5-hydroxytryptophan aggravated periodontitis-induced alveolar bone loss in rats. Arch Oral Biol. 2015;60:789-98 pubmed publisher
western blot; human	Zhang Y, Liu X, Li K, Bai J. Mycobacterium tuberculosis 10-kDa co-chaperonin regulates the expression levels of receptor activator of nuclear factor-ÎºB ligand and osteoprotegerin in human osteoblasts. Exp Ther Med. 2015;9:919-924 pubmed
western blot; rat	Yu X, Lv L, Zhang J, Zhang T, Xiao C, Li S. Expression of neuropeptides and bone remodeling-related factors during periodontal tissue regeneration in denervated rats. J Mol Histol. 2015;46:195-203 pubmed publisher
	He M, Wang J, Wang G, Tian Y, Jiang L, Ren Z, et al. Effect of glucocorticoids on osteoclast function in a mouse model of bone necrosis. Mol Med Rep. 2016;14:1054-60 pubmed publisher
	Yang X, Li F, Yang Y, Shen J, Zou R, Zhu P, et al. Efficacy and safety of echinacoside in a rat osteopenia model. Evid Based Complement Alternat Med. 2013;2013:926928 pubmed publisher

product information

sku :

bs-0431R

name :

OPG Polyclonal Antibody

category :

Primary Antibody

conjugation :

Unconjugated

host :

Rabbit

target protein :

OPG

modification :

Unmodified

clonality :

Polyclonal

isotype :

IgG

concentration :

1ug/ul

public immunogen range :

235-280/401

subcellular locations :

Secreted

source :

KLH conjugated synthetic peptide derived from mouse OPG

gene id link :

Entrez Gene: 18383

swiss prot :

O08712

swiss prot link :

Swiss Prot: O08712

applications :

WB, IHC-P, IF(IHC-P)

applications with dilutions :

WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)

cross reactive species :

Human, Mouse, Rat

size :

100 ul

price :

289.5 USD

background :

Acts as decoy receptor for TNFSF11/RANKL and thereby neutralizes its function in osteoclastogenesis. Inhibits the activation of osteoclasts and promotes osteoclast apoptosis in vitro. Bone homeostasis seems to depend on the local ratio between TNFSF11 and TNFRSF11B. May also play a role in preventing arterial calcification. May act as decoy receptor for TNFSF1/TRAIL and protect against apoptosis. TNFSF1/TRAIL binding blocks the inhibition of osteoclastogenesis.

purification :

Purified by Protein A.

storage :

Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for 12 months.

synonyms :

Opg; TR1; OCIF; Tumor necrosis factor receptor superfamily member 11B; Osteoclastogenesis inhibitory factor; Osteoprotegerin; Tnfrsf11b

lead time :

3 to 5 business days.

more info or order :

Bioss product webpage