TIMP-1 Polyclonal Antibody | Bioss bs-0415R product information

product summary

company name :

Bioss

product type :

antibody

product name :

TIMP-1 Polyclonal Antibody

catalog :

bs-0415R

quantity :

100 ul

price :

289.5 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat, rabbit

application :

western blot, immunocytochemistry, immunohistochemistry - paraffin section

more info or order :

Bioss product webpage

citations: 8

Published Application/Species/Sample/Dilution	Reference
western blot; human	Varghese S, Joseph M, S R A, B S U, Sreelekha T. The inhibitory effect of anti- tumor polysaccharide from Punica granatum on metastasis. Int J Biol Macromol. 2017;103:1000-1010 pubmed publisher
western blot; rat	Ni W, Ding H, Zhou H, Qiu Y, Tang L. Renoprotective effects of berberine through regulation of the MMPs/TIMPs system in streptozocin-induced diabetic nephropathy in rats. Eur J Pharmacol. 2015;764:448-56 pubmed publisher
immunohistochemistry - paraffin section; mouse	Lu H, Huang C, Shih C, Chang W, Tsai C, Lin F, et al. Dipeptidyl peptidase-4 inhibitor decreases abdominal aortic aneurysm formation through GLP-1-dependent monocytic activity in mice. PLoS ONE. 2015;10:e0121077 pubmed publisher
immunohistochemistry - paraffin section; rat	Jiang L, Zhou T, Liu H. Combined effects of the ATP-sensitive potassium channel opener pinacidil and simvastatin on pulmonary vascular remodeling in rats with monocrotaline-induced pulmonary arterial hypertension. Pharmazie. 2012;67:547-52 pubmed
immunohistochemistry - paraffin section; rabbit	Lu M, Cao J, Liu F, Li S, Chen J, Fu Q, et al. The effects of mycotoxins and selenium deficiency on tissue-engineered cartilage. Cells Tissues Organs. 2012;196:241-50 pubmed publisher
	Sassoli C, Chellini F, Squecco R, Tani A, Idrizaj E, Nosi D, et al. Low intensity 635 nm diode laser irradiation inhibits fibroblast-myofibroblast transition reducing TRPC1 channel expression/activity: New perspectives for tissue fibrosis treatment. Lasers Surg Med. 2016;48:318-32 pubmed publisher
	Watts R, Bilska I, Diab S, Dunster K, Bulmer A, Barnett A, et al. Novel 24-h ovine model of brain death to study the profile of the endothelin axis during cardiopulmonary injury. Intensive Care Med Exp. 2015;3:31 pubmed publisher
	Sassoli C, Nosi D, Tani A, Chellini F, Mazzanti B, Quercioli F, et al. Defining the role of mesenchymal stromal cells on the regulation of matrix metalloproteinases in skeletal muscle cells. Exp Cell Res. 2014;323:297-313 pubmed publisher

product information

sku :

bs-0415R

name :

TIMP-1 Polyclonal Antibody

category :

Primary Antibody

conjugation :

Unconjugated

host :

Rabbit

target protein :

TIMP-1NT

modification :

Unmodified

clonality :

Polyclonal

isotype :

IgG

concentration :

1ug/ul

public immunogen range :

95-145/207

subcellular locations :

Secreted

source :

KLH conjugated synthetic peptide derived from human TIMP-1

gene id link :

Entrez Gene: 7076

swiss prot :

P01033

swiss prot link :

Swiss Prot: P01033

applications :

WB, IHC-P, IF(IHC-P), IF(ICC)

applications with dilutions :

WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200), IF(ICC)(1:50-200)

cross reactive species :

Human, Mouse, Rat

size :

100 ul

price :

289.5 USD

background :

Metalloproteinase inhibitor that functions by forming one to one complexes with target metalloproteinases, such as collagenases, and irreversibly inactivates them by binding to their catalytic zinc cofactor. Acts on MMP1, MMP2, MMP3, MMP7, MMP8, MMP9, MMP1, MMP11, MMP12, MMP13 and MMP16. Does not act on MMP14. Also functions as a growth factor that regulates cell differentiation, migration and cell death and activates cellular signaling cascades via CD63 and ITGB1. Plays a role in integrin signaling. Mediates erythropoiesis in vitro; but, unlike IL3, it is species-specific, stimulating the growth and differentiation of only human and murine erythroid progenitors.

purification :

Purified by Protein A.

storage :

Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for 12 months.

synonyms :

EPA; EPO; HCI; CLGI; TIMP; Metalloproteinase inhibitor 1; Erythroid-potentiating activity; Fibroblast collagenase inhibitor; Collagenase inhibitor; Tissue inhibitor of metalloproteinases 1; TIMP-1; TIMP1

lead time :

3 to 5 business days.

more info or order :

Bioss product webpage