Fas Ligand Polyclonal Antibody | Bioss bs-0216R product information

product summary

company name :

Bioss

product type :

antibody

product name :

Fas Ligand Polyclonal Antibody

catalog :

bs-0216R

quantity :

100 ul

price :

289.5 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat, chicken

application :

western blot, immunocytochemistry, immunohistochemistry - paraffin section

more info or order :

Bioss product webpage

citations: 8

Published Application/Species/Sample/Dilution	Reference
western blot; mouse	Lv Y, Zheng J, Zhou Q, Jia L, Wang C, Liu N, et al. Antiproliferative and Apoptosis-inducing Effect of exo-Protoporphyrin IX based Sonodynamic Therapy on Human Oral Squamous Cell Carcinoma. Sci Rep. 2017;7:40967 pubmed publisher
western blot; human; 1:1000; fig 6	Wang S, Tian Q, An F. Growth inhibition and apoptotic effects of total flavonoids from Trollius chinensis on human breast cancer MCF-7 cells. Oncol Lett. 2016;12:1705-1710 pubmed
western blot; human	Song X, Li L, Shi Q, Lehmler H, Fu J, Su C, et al. Polychlorinated Biphenyl Quinone Metabolite Promotes p53-Dependent DNA Damage Checkpoint Activation, S-Phase Cycle Arrest and Extrinsic Apoptosis in Human Liver Hepatocellular Carcinoma HepG2 Cells. Chem Res Toxicol. 2015;28:2160-9 pubmed publisher
western blot; chicken	Chen C, Xie Q, Xue Y, Ji J, Chang S, Ma J, et al. Characterization of cytotoxicity-related gene expression in response to virulent Marek's disease virus infection in the bursa of Fabricius. Res Vet Sci. 2013;94:496-503 pubmed publisher
western blot; rat	Qi S, Fu W, Wang C, Liu C, Quan C, Kourouma A, et al. BPA-induced apoptosis of rat Sertoli cells through Fas/FasL and JNKs/p38 MAPK pathways. Reprod Toxicol. 2014;50:108-16 pubmed publisher
western blot; rat	Shi Y, Song Y, Wang Y, Wang Y, Liang X, Hu Y, et al. β-Benzene hexachloride induces apoptosis of rat Sertoli cells through generation of reactive oxygen species and activation of JNKs and FasL. Environ Toxicol. 2011;26:124-35 pubmed publisher
	Wang Y, Zhang J, Yang W, Luo H, Zhang J, Wang X. Lipopolysaccharide-induced expression of FAS ligand in cultured immature boar sertoli cells through the regulation of pro-inflammatory cytokines and miR-187. Mol Reprod Dev. 2015;82:880-91 pubmed publisher
	Shi Y, Song Y, Wang Y, Liang X, Hu Y, Guan X, et al. p,p'-DDE induces apoptosis of rat Sertoli cells via a FasL-dependent pathway. J Biomed Biotechnol. 2009;2009:181282 pubmed publisher

product information

sku :

bs-0216R

name :

Fas Ligand Polyclonal Antibody

category :

Primary Antibody

conjugation :

Unconjugated

host :

Rabbit

target protein :

Fas Ligand

modification :

Unmodified

clonality :

Polyclonal

isotype :

IgG

concentration :

1ug/ul

public immunogen range :

170-220/281

subcellular locations :

Extracellular

source :

KLH conjugated synthetic peptide derived from human Fas Ligand

gene id link :

Entrez Gene: 356

swiss prot :

P48023

swiss prot link :

Swiss Prot: P48023

applications :

WB, IHC-P, IF(IHC-P)

applications with dilutions :

WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)

cross reactive species :

Human, Mouse, Rat

size :

100 ul

price :

289.5 USD

background :

Cytokine that binds to TNFRSF6/FAS, a receptor that transduces the apoptotic signal into cells. May be involved in cytotoxic T-cell mediated apoptosis and in T-cell development. TNFRSF6/FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. Binding to the decoy receptor TNFRSF6B/DcR3 modulates its effects. The FasL intracellular domain (FasL ICD) cytoplasmic form induces gene transcription inhibition.

purification :

Purified by Protein A.

storage :

Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for 12 months.

synonyms :

APTL; FASL; CD178; CD95L; ALPS1B; CD95-L; TNFSF6; APT1LG1; Tumor necrosis factor ligand superfamily member 6; Apoptosis antigen ligand; CD95 ligand; Fas antigen ligand; Fas ligand; FASLG

lead time :

3 to 5 business days.

more info or order :

Bioss product webpage