CD31 Polyclonal Antibody | Bioss bs-0195R product information

product summary

company name :

Bioss

product type :

antibody

product name :

CD31 Polyclonal Antibody

catalog :

bs-0195R

quantity :

100 ul

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat, bovine, pigs , domestic rabbit

application :

western blot, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section

more info or order :

Bioss product webpage

citations: 6

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry - paraffin section; bovine	Kong H, Lee J, Youm H, Kim S, Lee J, Suh C, et al. Effect of treatment with angiopoietin-2 and vascular endothelial growth factor on the quality of xenografted bovine ovarian tissue in mice. PLoS ONE. 2017;12:e0184546 pubmed publisher
immunohistochemistry - paraffin section; rat	Korkmaz H, Ulrich M, Vogels S, de Wit T, van Zuijlen P, Krijnen P, et al. Neutrophil extracellular traps coincide with a pro-coagulant status of microcirculatory endothelium in burn wounds. Wound Repair Regen. 2017;25:609-617 pubmed publisher
immunohistochemistry - paraffin section; domestic rabbit	Wang L, Chen Q, Ke D, Li G. Ghrelin inhibits atherosclerotic plaque angiogenesis and promotes plaque stability in a rabbit atherosclerotic model. Peptides. 2017;90:17-26 pubmed publisher
immunohistochemistry - paraffin section; pigs	Struecker B, Hillebrandt K, Raschzok N, JÃ¶hrens K, Butter A, Tang P, et al. Implantation of a Tissue-Engineered Neo-Bile Duct in Domestic Pigs. Eur Surg Res. 2016;56:61-75 pubmed publisher
flow cytometry; domestic rabbit	Sun W, Ni X, Sun S, Cai L, Yu J, Wang J, et al. Adipose-Derived Stem Cells Alleviate Radiation-Induced Muscular Fibrosis by Suppressing the Expression of TGF-Î²1. Stem Cells Int. 2016;2016:5638204 pubmed publisher
	Wang S, Mi R, Cai Z, Wang Z, Zeng C, Xie Z, et al. DAPK1 Interacts with the p38 Isoform MAPK14, Preventing Its Nuclear Translocation and Stimulation of Bone Marrow Adipogenesis. Stem Cells. 2022;40:508-522 pubmed publisher

product information

sku :

bs-0195R

name :

CD31 Polyclonal Antibody

category :

Primary Antibody

conjugation :

Unconjugated

host :

Rabbit

target protein :

CD31

modification :

Unmodified

clonality :

Polyclonal

isotype :

IgG

concentration :

1ug/ul

public immunogen range :

718-738/738

subcellular locations :

Cytoplasm

source :

KLH conjugated synthetic peptide derived from human CD31

gene id link :

Entrez Gene: 5175

swiss prot :

P16284

swiss prot link :

Swiss Prot: P16284

applications :

WB, FCM, IHC-P, IF(IHC-P)

applications with dilutions :

WB(1:100-1000), FCM(1:20-100), IHC-P(1:100-500), IF(IHC-P)(1:50-200)

cross reactive species :

Human, Mouse, Rat, Rabbit

size :

100 ul

background :

Induces susceptibility to atherosclerosis (By similarity). Cell adhesion molecule which is required for leukocyte transendothelial migration (TEM) under most inflammatory conditions. Tyr-69 plays a critical role in TEM and is required for efficient trafficking of PECAM1 to and from the lateral border recycling compartment (LBRC) and is also essential for the LBRC membrane to be targeted around migrating leukocytes. Prevents phagocyte ingestion of closely apposed viable cells by transmitting 'detachment' signals, and changes function on apoptosis, promoting tethering of dying cells to phagocytes (the encounter of a viable cell with a phagocyte via the homophilic interaction of PECAM1 on both cell surfaces leads to the viable cell's active repulsion from the phagocyte. During apoptosis, the inside-out signaling of PECAM1 is somehow disabled so that the apoptotic cell does not actively reject the phagocyte anymore. The lack of this repulsion signal together with the interaction of the eat-me signals and their respective receptors causes the attachment of the apoptotic cell to the phagocyte, thus triggering the process of engulfment). Isoform Delta15 is unable to protect against apoptosis. Modulates BDKRB2 activation. Regulates bradykinin- and hyperosmotic shock-induced ERK1/2 activation in human umbilical cord vein cells (HUVEC).

purification :

Purified by Protein A.

storage :

Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for 12 months.

synonyms :

CD31; PECA1; GPIIA'; PECAM-1; endoCAM; CD31/EndoCAM; Platelet endothelial cell adhesion molecule; PECAM1

lead time :

3 to 5 business days.

more info or order :

Bioss product webpage