PI3 kinase p85 alpha subunit Antibody | Bioss bs-0128R product information

product summary

company name :

Bioss

product type :

antibody

product name :

PI3 kinase p85 alpha subunit Antibody

catalog :

bs-0128R

quantity :

100 ul

price :

289.5 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat, pig, rabbit

application :

western blot, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section

more info or order :

Bioss product webpage

citations: 6

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry - paraffin section; rat	Wang F, Wang S, Zhang Z, Lin Q, Liu Y, Xiao Y, et al. Defective insulin signaling and the protective effects of dimethyldiguanide during follicular development in the ovaries of polycystic ovary syndrome. Mol Med Rep. 2017;16:8164-8170 pubmed publisher
immunohistochemistry - paraffin section; rabbit	An X, Lv H, Tian J, He X, Ling N. Role of the PTEN/PI3K/VEGF pathway in the development of Kawasaki disease. Exp Ther Med. 2016;11:1318-1322 pubmed
western blot; pig; loading ...; fig 4a	Sun Y, Yang W, Luo H, Wang X, Chen Z, Zhang J, et al. Thyroid hormone inhibits the proliferation of piglet Sertoli cell via PI3K signaling pathway. Theriogenology. 2015;83:86-94 pubmed publisher
immunohistochemistry - paraffin section; human	Xu H, Huang Y, Xie Z, Lin L, Guo Y, Zhuang Z, et al. The expression of cytoglobin as a prognostic factor in gliomas: a retrospective analysis of 88 patients. BMC Cancer. 2013;13:247 pubmed publisher
immunohistochemistry - paraffin section; mouse western blot; mouse	Tian L, Bai X, Chen X, Fang J, Liu S, Chen J. Anti-diabetic effect of methylswertianin and bellidifolin from Swertia punicea Hemsl. and its potential mechanism. Phytomedicine. 2010;17:533-9 pubmed publisher
immunohistochemistry - paraffin section; mouse	Bai X, Chen X, Liu Y, Tian L, Zhou Q, Liu S, et al. Effects of water extract and crude polysaccharides from Liriope spicata var. prolifera on InsR/IRS-1/PI3K pathway and glucose metabolism in mice. J Ethnopharmacol. 2009;125:482-6 pubmed publisher

product information

sku :

bs-0128R

name :

PI3 kinase p85 alpha subunit Antibody

category :

Primary Antibody

conjugation :

Unconjugated

host :

Rabbit

target protein :

PI3 kinase p85 alpha subunit

modification :

Unmodified

clonality :

Polyclonal

isotype :

IgG

concentration :

1ug/ul

public immunogen range :

530-580/724

subcellular locations :

Intracellular

source :

KLH conjugated synthetic peptide derived from human PI3 kinase p85 subunit alpha

gene id link :

Entrez Gene: 5295

swiss prot :

P27986

swiss prot link :

Swiss Prot: P27986

applications :

WB, FCM, IHC-P, IF(IHC-P), IF(ICC)

applications with dilutions :

WB(1:100-1000), FCM(1:20-100), IHC-P(1:100-500), IF(IHC-P)(1:50-200), IF(ICC)(1:50-200)

cross reactive species :

Human, Mouse, Rat

size :

100 ul

price :

289.5 USD

background :

Binds to activated (phosphorylated) protein-Tyr kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p11 catalytic unit to the plasma membrane. Necessary for the insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin-sensitive tissues. Plays an important role in signaling in response to FGFR1, FGFR2, FGFR3, FGFR4, KITLG/SCF, KIT, PDGFRA and PDGFRB. Likewise, plays a role in ITGB2 signaling.

purification :

Purified by Protein A.

storage :

Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for 12 months.

synonyms :

p85; AGM7; GRB1; IMD36; p85-ALPHA; Phosphatidylinositol 3-kinase regulatory subunit alpha; PI3-kinase regulatory subunit alpha; PI3K regulatory subunit alpha; PtdIns-3-kinase regulatory subunit alpha; Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha; PI3-kinase subunit p85-alpha; PtdIns-3-kinase regulatory subunit p85-alpha; PIK3R1

lead time :

3 to 5 business days.

more info or order :

Bioss product webpage