Bax Polyclonal Antibody | Bioss bs-0127R product information

product summary

company name :

Bioss

product type :

antibody

product name :

Bax Polyclonal Antibody

catalog :

bs-0127R

quantity :

100 ul

price :

289.5 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat, pig, rabbit

application :

western blot, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section

more info or order :

Bioss product webpage

citations: 22

Published Application/Species/Sample/Dilution	Reference
western blot; rat	Rahman M, Ukiana J, Uson Lopez R, Sikder M, Saito T, Kurasaki M. Cytotoxic effects of cadmium and zinc co-exposure in PC12 cells and the underlying mechanism. Chem Biol Interact. 2017;269:41-49 pubmed publisher
immunohistochemistry - paraffin section; rat	Abdel Hamid N, El Azab M, Moustafa Y. Macrolide antibiotics differentially influence human HepG2 cytotoxicity and modulate intrinsic/extrinsic apoptotic pathways in rat hepatocellular carcinoma model. Naunyn Schmiedebergs Arch Pharmacol. 2017;390:379-395 pubmed publisher
western blot; rat	Yang J, Lu Y, Guo A. Platelet-rich plasma protects rat chondrocytes from interleukin-1?-induced apoptosis. Mol Med Rep. 2016;14:4075-4082 pubmed publisher
western blot; human; 1:1000; loading ...; fig 5a	Daverey A, Agrawal S. Curcumin alleviates oxidative stress and mitochondrial dysfunction in astrocytes. Neuroscience. 2016;333:92-103 pubmed publisher
immunohistochemistry - paraffin section; rat	Aksu E, Ã–zkaraca M, Kandemir F, Ã–mÃ¼r A, Eldutar E, KÃ¼Ã§Ã¼kler S, et al. Mitigation of paracetamol-induced reproductive damage by chrysin in male rats via reducing oxidative stress. Andrologia. 2016;48:1145-1154 pubmed publisher
western blot; mouse; 1:200; fig 3	Liu Y, Su X, Hao J, Chen M, Liu W, Liao X, et al. Overexpression of PRL7D1 in Leydig Cells Causes Male Reproductive Dysfunction in Mice. Int J Mol Sci. 2016;17: pubmed publisher
western blot; pig	He X, Han W, Hu S, Zhang M, Hua J, Peng S. Canonical Wnt signaling pathway contributes to the proliferation and survival in porcine pancreatic stem cells (PSCs). Cell Tissue Res. 2015;362:379-88 pubmed publisher
western blot; mouse	Park M, Kim D, Choi J, Heo Y, Park S. New role of irisin in hepatocytes: The protective effect of hepatic steatosis in vitro. Cell Signal. 2015;27:1831-9 pubmed publisher
western blot; rabbit	Huang G, Zou J, Shi J, Zhang D, Peng H, Zhang Q, et al. Electroacupuncture stimulates remodeling of extracellular matrix by inhibiting apoptosis in a rabbit model of disc degeneration. Evid Based Complement Alternat Med. 2015;2015:386012 pubmed publisher
immunohistochemistry - paraffin section; rat	She Y, Zhao H, Zhu Y, Han Y, Xia S, Bai C, et al. Aluminum Trichloride Disorders Bile Acid Secretion and Induces Hepatocyte Apoptosis in Rats. Cell Biochem Biophys. 2015;71:1569-77 pubmed publisher
western blot; mouse	Wang J, Lu M, Dai H, Zhang S, Wang H, Wei N. Esculetin, a coumarin derivative, exerts in vitro and in vivo antiproliferative activity against hepatocellular carcinoma by initiating a mitochondrial-dependent apoptosis pathway. Braz J Med Biol Res. 2015;48:245-53 pubmed publisher
immunoprecipitation; human	Qiu S, Cai Y, Gao X, Gu S, Liu Z. A small peptide derived from p53 linker region can resume the apoptotic activity of p53 by sequestering iASPP with p53. Cancer Lett. 2015;356:910-7 pubmed publisher
immunohistochemistry - paraffin section; mouse	Lin L, Bo X, Tan Y, Sun F, Song M, Zhao J, et al. Feasibility of Î²-sheet breaker peptide-H102 treatment for Alzheimer's disease based on Î²-amyloid hypothesis. PLoS ONE. 2014;9:e112052 pubmed publisher
western blot; mouse	Zhu Z, Wang Y, Liang Z, Wang W, Zhang H, Li B, et al. Regulation of cell transformation by Rb-controlled redox homeostasis. PLoS ONE. 2014;9:e102582 pubmed publisher
western blot; human	Lin C, Wang L, Wang H, Fang S, Zhang Q, Yang L, et al. Lithocarpus polystachyus REHD leaf aqueous extract inhibits human breast cancer growth in vitro and in vivo. Nutr Cancer. 2014;66:613-24 pubmed publisher
western blot; human	Ye B, Li J, Li Z, Yang J, Niu T, Wang S. Anti-tumor activity and relative mechanism of ethanolic extract of Marsdenia tenacissima (Asclepiadaceae) against human hematologic neoplasm in vitro and in vivo. J Ethnopharmacol. 2014;153:258-67 pubmed publisher
western blot; mouse	He X, Song W, Liu C, Chen S, Hua J. Rapamycin inhibits acrolein-induced apoptosis by alleviating ROS-driven mitochondrial dysfunction in male germ cells. Cell Prolif. 2014;47:161-71 pubmed publisher
western blot; rat	Rani N, Bharti S, Manchanda M, Nag T, Ray R, Chauhan S, et al. Regulation of heat shock proteins 27 and 70, p-Akt/p-eNOS and MAPKs by Naringin Dampens myocardial injury and dysfunction in vivo after ischemia/reperfusion. PLoS ONE. 2013;8:e82577 pubmed publisher
western blot; pig	Wang C, Ma W, Su Y. NF-?B pathway contributes to cadmium-induced apoptosis of porcine granulosa cells. Biol Trace Elem Res. 2013;153:403-10 pubmed publisher
western blot; mouse	Li G, Li Y, Liu S, Shi Y, Chi Y, Liu G, et al. Gremlin aggravates hyperglycemia-induced podocyte injury by a TGF?/smad dependent signaling pathway. J Cell Biochem. 2013;114:2101-13 pubmed publisher
western blot; rat	Tian X, Zhang L, Wang J, Dai J, Shen S, Yang L, et al. The protective effect of hyperbaric oxygen and Ginkgo biloba extract on A?25-35-induced oxidative stress and neuronal apoptosis in rats. Behav Brain Res. 2013;242:1-8 pubmed publisher
western blot; human	Chen J, Shi D, Liu X, Fang S, Zhang J, Zhao Y. Targeting SPARC by lentivirus-mediated RNA interference inhibits cervical cancer cell growth and metastasis. BMC Cancer. 2012;12:464 pubmed publisher

product information

sku :

bs-0127R

name :

Bax Polyclonal Antibody

category :

Primary Antibody

conjugation :

Unconjugated

host :

Rabbit

target protein :

Bax

modification :

Unmodified

clonality :

Polyclonal

isotype :

IgG

concentration :

1ug/ul

public immunogen range :

60-110/192

subcellular locations :

Mitochondrion

source :

KLH conjugated synthetic peptide derived from human Bax

gene id link :

Entrez Gene: 581

swiss prot :

Q07812

swiss prot link :

Swiss Prot: Q07812

applications :

WB, FCM, IHC-P, IF(IHC-P), IF(ICC)

applications with dilutions :

WB(1:100-1000), FCM(1:20-100), IHC-P(1:100-500), IF(IHC-P)(1:50-200), IF(ICC)(1:50-200)

cross reactive species :

Human, Mouse, Rat, Pig, Rabbit

size :

100 ul

price :

289.5 USD

background :

Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis.

purification :

Purified by Protein A.

storage :

Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for 12 months.

synonyms :

BCL2L4; Apoptosis regulator BAX; Bcl-2-like protein 4; Bcl2-L-4; BAX

lead time :

3 to 5 business days.

more info or order :

Bioss product webpage