Caspase 9 Polyclonal Antibody | Bioss bs-0049R product information

product summary

company name :

Bioss

product type :

antibody

product name :

Caspase 9 Polyclonal Antibody

catalog :

bs-0049R

quantity :

100 ul

price :

289.5 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat, dog

application :

western blot, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section

more info or order :

Bioss product webpage

citations: 6

Published Application/Species/Sample/Dilution	Reference
western blot; rat	Wang Y, Wang Y, Huang X, Yang Y, Zhao Y, Wei C, et al. Ibutilide protects against cardiomyocytes injury via inhibiting endoplasmic reticulum and mitochondrial stress pathways. Heart Vessels. 2017;32:208-215 pubmed publisher
western blot; rat	Wang Y, Xuan L, Cui X, Wang Y, Chen S, Wei C, et al. Ibutilide treatment protects against ER stress induced apoptosis by regulating calumenin expression in tunicamycin treated cardiomyocytes.. PLoS ONE. 2017;12:e0173469 pubmed publisher
western blot; mouse	Wang J, Lu M, Dai H, Zhang S, Wang H, Wei N. Esculetin, a coumarin derivative, exerts in vitro and in vivo antiproliferative activity against hepatocellular carcinoma by initiating a mitochondrial-dependent apoptosis pathway. Braz J Med Biol Res. 2015;48:245-53 pubmed publisher
immunohistochemistry - paraffin section; rat	Wang G, Han B, Zhou H, Wu L, Wang Y, Jia G, et al. Inhibition of hydrogen sulfide synthesis provides protection for severe acute pancreatitis rats via apoptosis pathway. Apoptosis. 2013;18:28-42 pubmed publisher
western blot; dog	Zhao J, Xu W, Yun F, Zhao H, Li W, Gong Y, et al. Chronic obstructive sleep apnea causes atrial remodeling in canines: mechanisms and implications. Basic Res Cardiol. 2014;109:427 pubmed publisher
	Pan B, Yang L, Wang J, Wang Y, Wang J, Zhou X, et al. C-Abl tyrosine kinase mediates neurotoxic prion peptide-induced neuronal apoptosis via regulating mitochondrial homeostasis. Mol Neurobiol. 2014;49:1102-16 pubmed publisher

product information

sku :

bs-0049R

name :

Caspase 9 Polyclonal Antibody

category :

Primary Antibody

conjugation :

Unconjugated

host :

Rabbit

target protein :

Caspase 9

modification :

Unmodified

clonality :

Polyclonal

isotype :

IgG

concentration :

1ug/ul

public immunogen range :

20-69/416

subcellular locations :

Cytoplasm

source :

KLH conjugated synthetic peptide derived from human Caspase 9 subunit p35

gene id link :

Entrez Gene: 842

swiss prot :

P55211

swiss prot link :

Swiss Prot: P55211

applications :

WB, FCM, IHC-P, IF(IHC-P)

applications with dilutions :

WB(1:100-1000), FCM(1:20-100), IHC-P(1:100-500), IF(IHC-P)(1:50-200)

cross reactive species :

Human, Mouse, Rat, Dog

size :

100 ul

price :

289.5 USD

background :

Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3. Promotes DNA damage-induced apoptosis in a ABL1/c-Abl-dependent manner. Proteolytically cleaves poly(ADP-ribose) polymerase (PARP). Isoform 2 lacks activity is an dominant-negative inhibitor of caspase-9.

purification :

Purified by Protein A.

storage :

Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for 12 months.

synonyms :

MCH6; APAF3; APAF-3; PPP1R56; ICE-LAP6; Caspase-9; CASP-9; Apoptotic protease Mch-6; Apoptotic protease-activating factor 3; ICE-like apoptotic protease 6; CASP9

lead time :

3 to 5 business days.

more info or order :

Bioss product webpage