Cytochrome C Polyclonal Antibody | Bioss bs-0013R product information

product summary

company name :

Bioss

product type :

antibody

product name :

Cytochrome C Polyclonal Antibody

catalog :

bs-0013R

quantity :

100 ul

price :

289.5 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section

more info or order :

Bioss product webpage

citations: 14

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry - paraffin section; rat	Abdel Hamid N, El Azab M, Moustafa Y. Macrolide antibiotics differentially influence human HepG2 cytotoxicity and modulate intrinsic/extrinsic apoptotic pathways in rat hepatocellular carcinoma model. Naunyn Schmiedebergs Arch Pharmacol. 2017;390:379-395 pubmed publisher
immunocytochemistry; rat	Liu Y, Chen Y, Du W, Wu X, Dong F, Qu X, et al. GluR3B Ab's induced oligodendrocyte precursor cells excitotoxicity via mitochondrial dysfunction. Brain Res Bull. 2017;130:60-66 pubmed publisher
western blot; human	Duan X, Li J, Xing X, Zhang Y, Li W, Zhao L, et al. Antioxidant tert-butylhydroquinone ameliorates arsenic-induced intracellular damages and apoptosis through induction of Nrf2-dependent antioxidant responses as well as stabilization of anti-apoptotic factor Bcl-2 in human keratinocytes. Free Radic Biol Med. 2016;94:74-87 pubmed publisher
western blot; human	Gu S, Chen C, Jiang X, Zhang Z. ROS-mediated endoplasmic reticulum stress and mitochondrial dysfunction underlie apoptosis induced by resveratrol and arsenic trioxide in A549 cells. Chem Biol Interact. 2016;245:100-9 pubmed publisher
western blot; human	Chen C, Gu S, Jiang X, Zhang Z. Nuclear translocation of nuclear factor kappa B is regulated by G protein signaling pathway in arsenite-induced apoptosis in HBE cell line. Environ Toxicol. 2016;31:1819-1833 pubmed publisher
western blot; human	Liao P, Li Y, Li H, Liu W. Organellar proteome analyses of ricin toxin-treated HeLa cells. Toxicol Ind Health. 2016;32:1166-78 pubmed publisher
western blot; rat	Li A, Li L, Sun X, Ni Y, Chen X, Guo A, et al. Increased Expression of Mitochondrial Inner-Membrane Protein Mpv17 After Intracerebral Hemorrhage in Adult Rats. Neurochem Res. 2015;40:1620-30 pubmed publisher
western blot; rat	Gao G, Yu Z, Yan J, Li J, Shen S, Jia B, et al. Poly (ADPâ€‘ribose) polymeraseâ€‘ and cytochromeÂ câ€‘mediated apoptosis induces hepatocyte injury in a rat model of hyperammoniaâ€‘induced hepatic failure. Mol Med Rep. 2015;11:4211-9 pubmed publisher
western blot; human	Gu S, Chen C, Jiang X, Zhang Z. Resveratrol synergistically triggers apoptotic cell death with arsenic trioxide via oxidative stress in human lung adenocarcinoma A549 cells. Biol Trace Elem Res. 2015;163:112-23 pubmed publisher
western blot; human	Chen C, Jiang X, Lai Y, Liu Y, Zhang Z. Resveratrol protects against arsenic trioxide-induced oxidative damage through maintenance of glutathione homeostasis and inhibition of apoptotic progression. Environ Mol Mutagen. 2015;56:333-46 pubmed publisher
western blot; human	Fang C, Zhang J, Qi D, Fan X, Luo J, Liu L, et al. Evodiamine induces G2/M arrest and apoptosis via mitochondrial and endoplasmic reticulum pathways in H446 and H1688 human small-cell lung cancer cells. PLoS ONE. 2014;9:e115204 pubmed publisher
western blot; mouse	Jiang H, Ren M, Jiang H, Wang J, Zhang J, Yin X, et al. Guanabenz delays the onset of disease symptoms, extends lifespan, improves motor performance and attenuates motor neuron loss in the SOD1 G93A mouse model of amyotrophic lateral sclerosis. Neuroscience. 2014;277:132-8 pubmed publisher
western blot; rat	Wang S, Wang S, Shan P, Song Z, Dai T, Wang R, et al. Mu-calpain mediates hippocampal neuron death in rats after lithium-pilocarpine-induced status epilepticus. Brain Res Bull. 2008;76:90-6 pubmed publisher
	Ye J, Wu G, Li X, Li Z, Zheng C, Liu X, et al. Millimeter Wave Treatment Inhibits Apoptosis of Chondrocytes via Regulation Dynamic Equilibrium of Intracellular Free Ca (2+). Evid Based Complement Alternat Med. 2015;2015:464161 pubmed publisher

product information

sku :

bs-0013R

name :

Cytochrome C Polyclonal Antibody

category :

Primary Antibody

conjugation :

Unconjugated

host :

Rabbit

target protein :

Cytochrome C

modification :

Unmodified

clonality :

Polyclonal

isotype :

IgG

concentration :

1ug/ul

public immunogen range :

50-89/105

subcellular locations :

Mitochondrion

source :

KLH conjugated synthetic peptide derived from human Cytochrome C

gene id link :

Entrez Gene: 54205

swiss prot :

P99999

swiss prot link :

Swiss Prot: P99999

applications :

WB, FCM, IHC-P, IF(IHC-P), IF(ICC)

applications with dilutions :

WB(1:100-1000), FCM(1:20-100), IHC-P(1:100-500), IF(IHC-P)(1:50-200), IF(ICC)(1:50-200)

cross reactive species :

Human, Mouse, Rat

size :

100 ul

price :

289.5 USD

background :

Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. Plays a role in apoptosis. Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of cytochrome c into the cytosol. Binding of cytochrome c to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases.

purification :

Purified by Protein A.

storage :

Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for 12 months.

synonyms :

CYC; HCS; THC4; Cytochrome c; CYCS

lead time :

3 to 5 business days.

more info or order :

Bioss product webpage