This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Biosensis
product type :
antibody
product name :
Guinea pig polyclonal antibody to human alpha MSH (138-150): Whole serum
catalog :
GP-030-50
quantity :
50 µl
clonality :
polyclonal
host :
guinea-pigs
conjugate :
nonconjugated
reactivity :
human, rat
product information
Catalog Number :
GP-030-50
Product Name :
Guinea pig polyclonal antibody to human alpha MSH (138-150): Whole serum
Host Species :
Guinea pig
Clonality :
Polyclonal
Product Type :
Purified
Size :
50 µl
Product Description :
Proopiomelanocortin (POMC) is the precursor of the melanocortin peptides alpha, beta and gamma. POMC neurons in the arcuate nucleus of the hypothalamus function as key central regulators of food intake and homeostatic control of energy balance in both rodents and non-human primates. MSH increases the pigmentation of skin by increasing the melanin production in melanocytes. MSH is produced in the pituitary gland and belongs to the POMC family.
CrossReactivity :
This antibody is known to react with human, rat and sheep. Other species have not yet been tested.
ALTnames :
Proopiomelanocortin; POMC; alpha-melanocyte stimulating hormone; melanotropin alpha
Immunogen :
A synthetic peptide (Ac-SYSMEHFRWGKPV) corresponding to the amino acids 138-150 from human Proopiomelanocortin (POMC). POMC is the precursor of the melanocortin peptides alpha, beta and gamma. The synthetic peptide was conjugated to a carrier protein to enhance the immunological response.
Specificity :
Specificity was demonstrated by immunohistochemistry.
Packaging :
Small box at room temperature
Application Summary :
IHC. A concentration of 1 in 2,000 is recommended for IHC. IHC performed in sheep brain (hypothalamus) demonstrates intense staining of cells. No staining is evident when the primary antibody is pre-absorbed with 0.5mg/ml of alpha MSH. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.
Storage :
It is recommended that a thawed sample is stored at 4ºC for no longer than 2 weeks. Allocation of appropriate anti-bacterial agent can increase shelf life by several weeks. Diluted serum should be prepared as required. Long term stability requires storage, preferably in small aliquots at -20ºC or lower. Glycerol (1:1) can be added to neat serum for additional stability if intended use does not prevent this.
products id :
269
company information
Biosensis
39 Winwood Street, Thebarton, South Australia, 5031
info@biosensis.com
http://www.biosensis.com
61 8 83527711
headquarters: Australia
Biosensis specializes in antibodies, proteins, ELISA kits and Staining kits for Neuroscience, with particular emphasis on neurotrophins and neurotrophin receptors for which Biosensis has been the worldwide leader and OEM supplier for nearly 30 years. In addition to neurotrophins, our neuroscience portfolio includes products for research in neurodegenerative diseases, neurodevelopment, and neuro-metabolism. Areas of focus include Alzheimer's, Parkinson's and ALS diseases, as well as autophagy and metabolic and stress disorders including metabolic syndrome research, obesity, and neuroimmunology and inflammation.