Chicken polyclonal antibody to Microtubule Associated Protein 2 (MAP2)

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Biosensis

product type :

antibody

product name :

Chicken polyclonal antibody to Microtubule Associated Protein 2 (MAP2)

catalog :

C-1382-50

quantity :

50 µl

clonality :

polyclonal

host :

chicken

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

immunohistochemistry, immunocytochemistry

citations: 2

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry; mouse; loading ...; fig 1b	Awasthi A, Ramachandran B, Ahmed S, Benito E, Shinoda Y, Nitzan N, et al. Synaptotagmin-3 drives AMPA receptor endocytosis, depression of synapse strength, and forgetting. Science. 2019;363: pubmed publisher
immunocytochemistry; rat; 1:5000; loading ...; fig 1a	Wolfes A, Ahmed S, Awasthi A, Stahlberg M, Rajput A, Magruder D, et al. A novel method for culturing stellate astrocytes reveals spatially distinct Ca2+ signaling and vesicle recycling in astrocytic processes. J Gen Physiol. 2017;149:149-170 pubmed publisher

product information

Catalog Number :

C-1382-50

Product Name :

Chicken polyclonal antibody to Microtubule Associated Protein 2 (MAP2)

Host Species :

Chicken

Clonality :

Polyclonal

Product Type :

Purified

Size :

50 µl

list of Pubmed id :

17611279

Isotype :

IgY

Product Description :

Microtubules are 25nm diameter protein rods found in most kinds of eukarytic cells. They are polymerized from a dimeric subunit made of one a subunit and one b tubulin subunit. Microtubules are associated with a family of proteins called microtubule associated proteins (MAPs), which includes the protein t (tau) and a group of proteins referred to as MAP1, MAP2, MAP3, MAP4 and MAP5. MAP2 is made up of two ~280kDa apparent molecular weight bands referred to as MAP2a and MAP2b. A third lower molecular weight form, usually called MAP2c, corresponds to a pair of protein bands running at ~70kDa on SDS-PAGE gels. All these MAP2 forms are derived from a single gene by alternate transcription, and all share a C-terminal sequence which includes either three or four microtubule binding peptide sequences, which are very similar to those found in the related microtubule binding protein t (tau). MAP2 isoforms are expressed only in neuronal cells and specifically in the perikarya and dendrites of these cells. Antibodies to MAP2 are therefore excellent markers on neuronal cells, their perikarya and neuronal dendrites.

CrossReactivity :

Hu, Rat, Ms, Bov

ALTnames :

Microtubule-associated protein 2; MAP-2; MAP2;

Immunogen :

Bovine MAP2 isolated from brain by the GTP microtubule cycling method.

Specificity :

The specificity of this antibody has been confirmed by IC.

Packaging :

Small box at room temperature

Application Summary :

Immunocytochemistry (IC) at suggested dilution of 1:2,500-5,000. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.

Storage :

After reconstitution of lyophilised antibody, aliquot and store at -20°C for a higher stability. Avoid freeze-thaw cycles.

Product References :

1. Dziennis S. et al (2007) Role of signal transducer and activator of transcription-3 in estradiol-mediated neuroprotection. J Neurosci. 2007 Jul 4;27(27):7268-74. .

products id :

997