Mlkl antibody | Biorbyt orb32399 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Biorbyt

product type :

antibody

product name :

Mlkl antibody

catalog :

orb32399

quantity :

100 ug

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunocytochemistry, immunohistochemistry - paraffin section, western blot knockout validation, immunohistochemistry knockout validation

citations: 5

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry knockout validation; mouse; loading ...; fig s2c western blot knockout validation; mouse; loading ...; fig s2c immunohistochemistry - paraffin section; mouse; loading ...; fig 2c	Günther C, He G, Kremer A, Murphy J, Petrie E, Amann K, et al. The pseudokinase MLKL mediates programmed hepatocellular necrosis independently of RIPK3 during hepatitis. J Clin Invest. 2016;126:4346-4360 pubmed publisher
western blot; mouse; loading ...; fig 5a	Choi S, Shin S, Lee H, Sohn K, Yoon S, Kim J. 1-Palmitoyl-2-linoleoyl-3-acetyl-rac-glycerol ameliorates chemoradiation-induced oral mucositis. Oral Dis. 2020;26:111-121 pubmed publisher
western blot; mouse; 1:1000; loading ...; fig 3h	Frank T, Tuppi M, Hugle M, Dötsch V, van Wijk S, Fulda S. Cell cycle arrest in mitosis promotes interferon-induced necroptosis. Cell Death Differ. 2019;: pubmed publisher
	Fuchslocher Chico J, Falk Paulsen M, Luzius A, Saggau C, Ruder B, Bolik J, et al. The enhanced susceptibility of ADAM-17 hypomorphic mice to DSS-induced colitis is not ameliorated by loss of RIPK3, revealing an unexpected function of ADAM-17 in necroptosis. Oncotarget. 2018;9:12941-12958 pubmed publisher
	Cao M, Fang J, Wang X, Wang Y, Duan K, Ye F, et al. Activation of AMP-activated protein kinase (AMPK) aggravated postoperative cognitive dysfunction and pathogenesis in aged rats. Brain Res. 2018;1684:21-29 pubmed publisher

product information

Catalog Number :

orb32399

Product Name :

Mlkl antibody

Product Type :

Primary antibodies

Host Species :

Rabbit

Clonality :

Polyclonal

Conjugation :

Unconjugated

Isotype :

IgG

Size :

100 ug

Product Description :

Rabbit polyclonal antibody to MlKl (mixed lineage kinase domain-like) is a 471 amino acid protein that contains one protein kinase domain which is thought to be catalytically inactive. Chromosome 16, which is associated with a variety of genetic disorders, encodes over 900 genes and comprises nearly 3% of the human genome. The rare disorder Rubinstein-Taybi syndrome is associated with chromosome 16, as is Crohn's disease, which is a gastrointestinal inflammatory condition.

SpeciesSummary :

Guinea pig,Human,Mouse,Rat

ALTnames :

anti-Mixed lineage kinase domain-like protein antibody, anti-Mlkl antibody

Immunogen :

KLH conjugated synthetic peptide derived from human Mlkl. Please contact us for the exact immunogen sequence. The peptide is available as orb374793.

Purity :

Polyclonal antibodies are purified by peptide affinity chromatography

Buffer :

10 mM PBS, 0.02% sodium azide

Concentration :

- 100 μg (in 200 μl): 0.5 mg/ml- 200 μg (in 400 μl): 0.5 mg/ml

Application Summary :

WB: 1:200-2000, IHC-P: 1:100-500, IF/ICC: 1:100-500

Storage :

Store at 4°C for up to two weeks. For long term storage, aliquot and store at -20°C, avoid freeze/thaw cycles.

Count image :