product summary
company name :
Biogenex
product type :
antibody
product name :
CDX2
catalog :
MU392A-UC
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
CDX2-88
reactivity :
human, mouse, bovine, swine
application :
immunohistochemistry, immunocytochemistry, chromatin immunoprecipitation, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
citations: 49
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - paraffin section; mouse; 1:300; loading ...; fig 7d
Kim J, Fei L, Yin W, Coquenlorge S, Rao Bhatia A, Zhang X, et al. Single cell and genetic analyses reveal conserved populations and signaling mechanisms of gastrointestinal stromal niches. Nat Commun. 2020;11:334 pubmed publisher
  • immunohistochemistry; mouse; loading ...; fig s3b
Senft A, Costello I, King H, Mould A, Bikoff E, Robertson E. Combinatorial Smad2/3 Activities Downstream of Nodal Signaling Maintain Embryonic/Extra-Embryonic Cell Identities during Lineage Priming. Cell Rep. 2018;24:1977-1985.e7 pubmed publisher
  • immunohistochemistry; mouse; loading ...; fig 2a
Watanabe Y, Miyasaka K, Kubo A, Kida Y, Nakagawa O, Hirate Y, et al. Notch and Hippo signaling converge on Strawberry Notch 1 (Sbno1) to synergistically activate Cdx2 during specification of the trophectoderm. Sci Rep. 2017;7:46135 pubmed publisher
  • immunocytochemistry; mouse; 1:200; loading ...; fig 3d
Lo Nigro A, de Jaime Soguero A, Khoueiry R, Cho D, Ferlazzo G, Perini I, et al. PDGFR?+ Cells in Embryonic Stem Cell Cultures Represent the In Vitro Equivalent of the Pre-implantation Primitive Endoderm Precursors. Stem Cell Reports. 2017;8:318-333 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:500; loading ...
McCracken K, Aihara E, Martin B, Crawford C, Broda T, Treguier J, et al. Wnt/β-catenin promotes gastric fundus specification in mice and humans. Nature. 2017;541:182-187 pubmed publisher
  • immunocytochemistry; mouse; 1:200; loading ...; fig 4c
Zhou L, Baibakov B, Canagarajah B, Xiong B, Dean J. Genetic mosaics and time-lapse imaging identify functions of histone H3.3 residues in mouse oocytes and embryos. Development. 2017;144:519-528 pubmed publisher
  • immunohistochemistry; human; 1:500; loading ...; fig st4
Tsai Y, Nattiv R, Dedhia P, Nagy M, Chin A, Thomson M, et al. In vitro patterning of pluripotent stem cell-derived intestine recapitulates in vivo human development. Development. 2017;144:1045-1055 pubmed publisher
  • immunohistochemistry; human; fig 3c
Tuncel D, Roa J, Araya J, Bellolio E, Villaseca M, Tapia O, et al. Poorly cohesive cell (diffuse-infiltrative/signet ring cell) carcinomas of the gallbladder: clinicopathological analysis of 24 cases identified in 628 gallbladder carcinomas. Hum Pathol. 2017;60:24-31 pubmed publisher
  • chromatin immunoprecipitation; human; loading ...; fig 2c
Coskun M, Soendergaard C, Joergensen S, Dahlgaard K, Riis L, Nielsen O, et al. Regulation of Laminin γ2 Expression by CDX2 in Colonic Epithelial Cells Is Impaired During Active Inflammation. J Cell Biochem. 2017;118:298-307 pubmed publisher
  • immunohistochemistry; mouse; 1:100; loading ...; fig 3b
  • immunohistochemistry; bovine; 1:100; loading ...; fig 7a
Sauvegarde C, Paul D, Bridoux L, Jouneau A, Degrelle S, Hue I, et al. Dynamic Pattern of HOXB9 Protein Localization during Oocyte Maturation and Early Embryonic Development in Mammals. PLoS ONE. 2016;11:e0165898 pubmed publisher
  • immunohistochemistry; mouse; loading ...; fig s2b
Zheng X, Yang P, Lackford B, Bennett B, Wang L, Li H, et al. CNOT3-Dependent mRNA Deadenylation Safeguards the Pluripotent State. Stem Cell Reports. 2016;7:897-910 pubmed publisher
  • immunocytochemistry; mouse; 1:200
  • immunohistochemistry; mouse; 1:200; fig 3
Martin Gonzalez J, Morgani S, Bone R, Bonderup K, Abelchian S, Brakebusch C, et al. Embryonic Stem Cell Culture Conditions Support Distinct States Associated with Different Developmental Stages and Potency. Stem Cell Reports. 2016;7:177-91 pubmed publisher
  • immunohistochemistry; mouse; 1:200; loading ...; fig 4a
Maître J, Turlier H, Illukkumbura R, Eismann B, Niwayama R, Nedelec F, et al. Asymmetric division of contractile domains couples cell positioning and fate specification. Nature. 2016;536:344-348 pubmed publisher
  • immunocytochemistry; bovine; fig 1
Herrick J, Lyons S, Greene A, Broeckling C, Schoolcraft W, Krisher R. Direct and Osmolarity-Dependent Effects of Glycine on Preimplantation Bovine Embryos. PLoS ONE. 2016;11:e0159581 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:100; fig 3
Fessler E, Drost J, van Hooff S, Linnekamp J, Wang X, Jansen M, et al. TGFβ signaling directs serrated adenomas to the mesenchymal colorectal cancer subtype. EMBO Mol Med. 2016;8:745-60 pubmed publisher
  • immunocytochemistry; human; 1:10; fig 1
Deglincerti A, Croft G, Pietila L, Zernicka Goetz M, Siggia E, Brivanlou A. Self-organization of the in vitro attached human embryo. Nature. 2016;533:251-4 pubmed publisher
  • immunocytochemistry; swine; 1:50; fig 3
Xue B, Li Y, He Y, Wei R, Sun R, Yin Z, et al. Porcine Pluripotent Stem Cells Derived from IVF Embryos Contribute to Chimeric Development In Vivo. PLoS ONE. 2016;11:e0151737 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:80; fig 2
Xuan S, Sussel L. GATA4 and GATA6 regulate pancreatic endoderm identity through inhibition of hedgehog signaling. Development. 2016;143:780-6 pubmed publisher
  • immunohistochemistry; mouse; 1:100; loading ...; fig 6a
Li Y, Seah M, O NEILL C. Mapping global changes in nuclear cytosine base modifications in the early mouse embryo. Reproduction. 2016;151:83-95 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:200; loading ...; fig 6c, d
Sulahian R, Chen J, Arany Z, Jadhav U, Peng S, Rustgi A, et al. SOX15 governs transcription in human stratified epithelia and a subset of esophageal adenocarcinomas. Cell Mol Gastroenterol Hepatol. 2015;1:598-609.e6 pubmed
  • immunocytochemistry; human; 1:100; fig 4
Freedman B, Brooks C, Lam A, Fu H, Morizane R, Agrawal V, et al. Modelling kidney disease with CRISPR-mutant kidney organoids derived from human pluripotent epiblast spheroids. Nat Commun. 2015;6:8715 pubmed publisher
  • immunocytochemistry; mouse; 1:250; fig 3
O Shaughnessy Kirwan A, Signolet J, Costello I, Gharbi S, Hendrich B. Constraint of gene expression by the chromatin remodelling protein CHD4 facilitates lineage specification. Development. 2015;142:2586-97 pubmed publisher
  • immunocytochemistry; mouse; 1:100; fig 5
Yu S, Yehia G, Wang J, Stypulkowski E, Sakamori R, Jiang P, et al. Global ablation of the mouse Rab11a gene impairs early embryogenesis and matrix metalloproteinase secretion. J Biol Chem. 2014;289:32030-43 pubmed publisher
  • immunocytochemistry; mouse; 1:400; loading ...; fig s1d
Roper S, Chrysanthou S, Senner C, Sienerth A, Gnan S, Murray A, et al. ADP-ribosyltransferases Parp1 and Parp7 safeguard pluripotency of ES cells. Nucleic Acids Res. 2014;42:8914-27 pubmed publisher
  • immunocytochemistry; mouse; fig 3b
Turco M, Furia L, Dietze A, Fernandez Diaz L, Ronzoni S, Sciullo A, et al. Cellular heterogeneity during embryonic stem cell differentiation to epiblast stem cells is revealed by the ShcD/RaLP adaptor protein. Stem Cells. 2012;30:2423-36 pubmed publisher
Lin Z, Li Y, Jin Y, Kim N. A Maternal Transcription Factor, Junction Mediating and Regulatory Protein is Required for Preimplantation Development in the Mouse. Dev Reprod. 2019;23:285-295 pubmed publisher
Benchetrit H, Jaber M, Zayat V, Sebban S, Pushett A, Makedonski K, et al. Direct Induction of the Three Pre-implantation Blastocyst Cell Types from Fibroblasts. Cell Stem Cell. 2019;24:983-994.e7 pubmed publisher
Genga R, Kernfeld E, Parsi K, Parsons T, Ziller M, Maehr R. Single-Cell RNA-Sequencing-Based CRISPRi Screening Resolves Molecular Drivers of Early Human Endoderm Development. Cell Rep. 2019;27:708-718.e10 pubmed publisher
Schumacher D, Andrieux G, Boehnke K, Keil M, Silvestri A, Silvestrov M, et al. Heterogeneous pathway activation and drug response modelled in colorectal-tumor-derived 3D cultures. PLoS Genet. 2019;15:e1008076 pubmed publisher
Li H, Zhao C, Xu J, Xu Y, Cheng C, Liu Y, et al. Rapid generation of gene-targeted EPS-derived mouse models through tetraploid complementation. Protein Cell. 2019;10:20-30 pubmed publisher
Frum T, Murphy T, Ralston A. HIPPO signaling resolves embryonic cell fate conflicts during establishment of pluripotency in vivo. elife. 2018;7: pubmed publisher
Gontan C, Mira Bontenbal H, Magaraki A, Dupont C, Barakat T, Rentmeester E, et al. REX1 is the critical target of RNF12 in imprinted X chromosome inactivation in mice. Nat Commun. 2018;9:4752 pubmed publisher
Xu Y, Luo X, Fang Z, Zheng X, Zeng Y, Zhu C, et al. Transcription coactivator Cited1 acts as an inducer of trophoblast-like state from mouse embryonic stem cells through the activation of BMP signaling. Cell Death Dis. 2018;9:924 pubmed publisher
Danielsen E, Olsen A, Coskun M, Nonboe A, Larsen S, Dahlgaard K, et al. Intestinal regulation of suppression of tumorigenicity 14 (ST14) and serine peptidase inhibitor, Kunitz type -1 (SPINT1) by transcription factor CDX2. Sci Rep. 2018;8:11813 pubmed publisher
Molotkov A, Soriano P. Distinct mechanisms for PDGF and FGF signaling in primitive endoderm development. Dev Biol. 2018;442:155-161 pubmed publisher
Zylicz J, Borensztein M, Wong F, Huang Y, Lee C, Dietmann S, et al. G9a regulates temporal preimplantation developmental program and lineage segregation in blastocyst. elife. 2018;7: pubmed publisher
Ye B, Liu B, Hao L, Zhu X, Yang L, Wang S, et al. Klf4 glutamylation is required for cell reprogramming and early embryonic development in mice. Nat Commun. 2018;9:1261 pubmed publisher
Bogliotti Y, Wu J, Vilarino M, Okamura D, Soto D, Zhong C, et al. Efficient derivation of stable primed pluripotent embryonic stem cells from bovine blastocysts. Proc Natl Acad Sci U S A. 2018;115:2090-2095 pubmed publisher
Fogarty N, McCarthy A, Snijders K, Powell B, Kubikova N, Blakeley P, et al. Genome editing reveals a role for OCT4 in human embryogenesis. Nature. 2017;550:67-73 pubmed publisher
Pinto R, Hansen L, Hintze J, Almeida R, Larsen S, Coskun M, et al. Precise integration of inducible transcriptional elements (PrIITE) enables absolute control of gene expression. Nucleic Acids Res. 2017;45:e123 pubmed publisher
Miyamoto K, Tajima Y, Yoshida K, Oikawa M, Azuma R, Allen G, et al. Reprogramming towards totipotency is greatly facilitated by synergistic effects of small molecules. Biol Open. 2017;6:415-424 pubmed publisher
Yang Y, Liu B, Xu J, Wang J, Wu J, Shi C, et al. Derivation of Pluripotent Stem Cells with In Vivo Embryonic and Extraembryonic Potency. Cell. 2017;169:243-257.e25 pubmed publisher
Arora N, Imran Alsous J, Guggenheim J, Mak M, Múnera J, Wells J, et al. A process engineering approach to increase organoid yield. Development. 2017;144:1128-1136 pubmed publisher
Saiz N, Williams K, Seshan V, Hadjantonakis A. Asynchronous fate decisions by single cells collectively ensure consistent lineage composition in the mouse blastocyst. Nat Commun. 2016;7:13463 pubmed publisher
Yang Y, Arenas Hernandez M, Gomez Lopez N, Dai J, Parker G, Puscheck E, et al. Hypoxic Stress Forces Irreversible Differentiation of a Majority of Mouse Trophoblast Stem Cells Despite FGF4. Biol Reprod. 2016;95:110 pubmed
Karamchandani D, Lehman H, Ohanessian S, Massé J, Welsh P, Odze R, et al. Increasing diagnostic accuracy to grade dysplasia in Barrett's esophagus using an immunohistochemical panel for CDX2, p120ctn, c-Myc and Jagged1. Diagn Pathol. 2016;11:23 pubmed publisher
Zheng J, Qiao L, Sun X, Qi J, Ren H, Wei G, et al. Overexpression of caudal-related homeobox transcription factor 2 inhibits the growth of transplanted colorectal tumors in nude mice. Mol Med Rep. 2015;12:3409-3415 pubmed publisher
Sulahian R, Casey F, Shen J, Qian Z, Shin H, Ogino S, et al. An integrative analysis reveals functional targets of GATA6 transcriptional regulation in gastric cancer. Oncogene. 2014;33:5637-48 pubmed publisher
Abe M, Havre P, Urasaki Y, Ohnuma K, Morimoto C, Dang L, et al. Mechanisms of confluence-dependent expression of CD26 in colon cancer cell lines. BMC Cancer. 2011;11:51 pubmed publisher
company information
Biogenex
49026 Milmont Drive Fremont, CA 94538
support@biogenex.com
http://www.biogenex.com
headquarters: USA