AMACR (P504S) clone 13H4 | BioLogo P504S-G product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

BioLogo

product type :

antibody

product name :

AMACR (P504S) clone 13H4

catalog :

P504S-G

quantity :

5 ml

price :

120 USD

clonality :

monoclonal

host :

rabbit

conjugate :

nonconjugated

clone name :

13H4

reactivity :

human

application :

immunohistochemistry, immunohistochemistry - paraffin section, immunohistochemistry - free floating section

citations: 5

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry - free floating section; human; fig 1	Bonkhoff H. Significance of prostate cancer missed on needle biopsy tools for retrieving missed cancer. Prostate. 2016;76:369-75 pubmed publisher
immunohistochemistry; human; 1:200	Noske A, Zimmermann A, Caduff R, Varga Z, Fink D, Moch H, et al. Alpha-methylacyl-CoA racemase (AMACR) expression in epithelial ovarian cancer. Virchows Arch. 2011;459:91-7 pubmed publisher
immunohistochemistry - paraffin section; human; 1:100	Hailemariam S, Vosbeck J, Cathomas G, Zlobec I, Mattarelli G, Eichenberger T, et al. Can molecular markers stratify the diagnostic value of high-grade prostatic intraepithelial neoplasia?. Hum Pathol. 2011;42:702-9 pubmed publisher
immunohistochemistry - paraffin section; human; 1:200	Gunia S, May M, Scholmann K, Störkel S, Hoschke B, Koch S, et al. Expression of alpha-methylacyl-CoA racemase correlates with histopathologic grading in noninvasive bladder cancer. Virchows Arch. 2008;453:165-70 pubmed publisher
immunohistochemistry - paraffin section; human; 1:25	Went P, Sauter G, Oberholzer M, Bubendorf L. Abundant expression of AMACR in many distinct tumour types. Pathology. 2006;38:426-32 pubmed

product information

Catalog Number :

P504S-G

Product Name :

AMACR (P504S) clone 13H4

Host Species :

Rabbit

Product Type :

Primary Antibody

Size :

5 ml

List Price :

120 USD

Clone :

13H4

Isotype :

IgG

CrossReactivity :

Human

Background :

Alpha-Methylacyl-CoA Racemase (AMACR) has originally been isolated and characterised from rat liver (Schmitz et al., 1994, later also from human liver (Schmitz et al., 1995). It is a peroxisomal and mitochondrial enzyme, specifically involved in beta-oxidation of branched fatty acids and fatty acid metabolites. Interestingly this enzyme by cDNA-subtraction and microarray screening has also been detected in prostate carcinoma (Jiang et al., 2001). cDNA of human AMACR consists 1621 bases encoding a 382 AA protein.

Immunogen :

Human recombinant AMACR (P504S) protein, whole sequence

Specificity :

Human AMACR (P504S) protein, Alpha-Methylacyl CoA Racemase

Concentration :

0,5 µg/ml

Application Summary :

IHC(C, P)

Storage :

2-8°C

General References :

1. Schmitz W., Albers C., Fingerhut R., and Conzelmann E. (1995) Purification and characterization of an alpha-methylacyl-CoA racemase from human liver. Eur J. Biochem. 231(3); 815-822.

Product References :

2. Babcook J.S., Leslie K.B., Olsen O.A., et al. (1996) A novel strategy for generating monoclonal antibodies from single isolated lymphocytes producing antibodies of defined specificities. Proc. Natl. Acad. Sci. USA 93; 7843-7848.