Insulin, human | BioLogo IN115-0.5 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

BioLogo

product type :

antibody

product name :

Insulin, human

catalog :

IN115-0.5

quantity :

0.5 ml

price :

110 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

clone name :

polyclonal

reactivity :

human, rat

application :

immunohistochemistry

product information

Catalog Number :

IN115-0.5

Product Name :

Insulin, human

Host Species :

Rabbit

Product Type :

Primary Antibody

Size :

0.5 ml

List Price :

110 USD

Clone :

polyclonal

Isotype :

CrossReactivity :

Human, pig, rat

Background :

Insulin is a polypeptide hormone that is produced in the B-cells of pancreatic islets as a pro-hormone which is transformed into active insulin after cleavage of the s. c. C-peptide. The MW of insulin is app. 5800 Da. It consists of an alpha- and beta-chain, which are connected by two disulfide bridges. The hormone regulates the uptake of glucose into the cell. A deficit of insulin production causes Diabetes mellitus. Over-production of insulin (together with hyperglycaemia) usually is caused by insulinoma, which are the most frequently occurring pancreatic tumours.

Immunogen :

Purified porcine Insulin

Application Summary :

IHC(C, P)

Storage :

2-8°C

General References :

1. Roth J. (1982) The protein A-Gold (pAg) technique- A qualitative and quantitative approach for antigen localization on thin sections. In: G.R. Bullock and P. Petrusz eds. Techniques in Immunocytochemistry Academic Press, London. Vol. 1, pp. 107-133.

Product References :

2. Weidenheim K.M., et al. (1983) Hyperinsulinemic hypoglycemia in adults with islet-cell hyperplasia and degranulation of exocrine cells of the pancreas. Amer. J. Clin. Pathol. 79; 14ff.