Alpha-DEFENSIN (1-3), HNP1-3 | BioLogo HNP103 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

BioLogo

product type :

antibody

product name :

Alpha-DEFENSIN (1-3), HNP1-3

catalog :

HNP103

quantity :

100 µg

price :

560 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

Def-3

reactivity :

human

application :

immunohistochemistry, FACS, immunohistochemistry - paraffin section

citations: 1

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry - paraffin section; human; 1:200; loading ...; fig 1c	Bierkarre H, Harder J, Cuthbert R, Emery P, Leuschner I, Mrowietz U, et al. Differential expression of antimicrobial peptides in psoriasis and psoriatic arthritis as a novel contributory mechanism for skin and joint disease heterogeneity. Scand J Rheumatol. 2016;45:188-96 pubmed publisher

product information

Catalog Number :

HNP103

Product Name :

Alpha-DEFENSIN (1-3), HNP1-3

Host Species :

Mouse

Product Type :

Primary Antibody

Size :

100 µg

List Price :

560 USD

Clone :

DEF-3

Isotype :

IgG1

CrossReactivity :

Human, cross-reactivity with rhesus monkey and primates expected

Background :

Human defensins are Cys-rich antimicrobial peptides which specifically react against Gram-negative bacteria. Originally defensins were isolated from hemolysates, but they can also be found on the cell surface of epithelia of the urogenital tract, lung, and trachea. In leukocytes defensins are stored in granules being released into phagolysosomes for the destruction of incorporated microorganisms. Amino acid sequences of alpha-defensins 1-4 (HNP1-4) and beta-Defensins 1-4 (HBD1-4) are known.

Immunogen :

Native Defensins

Specificity :

Human Neutrophil Peptides (HNP1-3) syn. alpha-Defensins 1-3, reactivity with HNP-4 not tested

Concentration :

200 µg/ml IgG after reconstitution with 0,5 ml distilled water

Application Summary :

IHC(C, P), FACS

Storage :

-20'°C'

General References :

1. Ganz T. et al. (1985) J. Clin. Invest., 76; 1427 ff

Product References :

2. Ganz T., et al. (1992) Med. Microbiol. Immunol. 181; 99ff