HCG, Human Chorionic Gonadotrophin | BioLogo HC100 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

BioLogo

product type :

antibody

product name :

HCG, Human Chorionic Gonadotrophin

catalog :

HC100

quantity :

1 ml

price :

180 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

H-298-12

reactivity :

human

application :

western blot, immunocytochemistry, immunohistochemistry - paraffin section

citations: 3

Published Application/Species/Sample/Dilution	Reference
immunocytochemistry; human; 1:10; fig 1.c,d	Siwetz M, Sundl M, Kolb D, Hiden U, Herse F, Huppertz B, et al. Placental fractalkine mediates adhesion of THP-1 monocytes to villous trophoblast. Histochem Cell Biol. 2015;143:565-74 pubmed publisher
western blot; human; 1:10	Siwetz M, Blaschitz A, Kremshofer J, Bilic J, Desoye G, Huppertz B, et al. Metalloprotease dependent release of placenta derived fractalkine. Mediators Inflamm. 2014;2014:839290 pubmed publisher
immunohistochemistry - paraffin section; human; 1:15	Gauster M, Siwetz M, Huppertz B. Fusion of villous trophoblast can be visualized by localizing active caspase 8. Placenta. 2009;30:547-50 pubmed publisher

product information

Catalog Number :

HC100

Product Name :

HCG, Human Chorionic Gonadotrophin

Host Species :

Mouse

Product Type :

Primary Antibody

Size :

1 ml

List Price :

180 USD

Clone :

H-298-12

Isotype :

IgG1

CrossReactivity :

Human

Background :

HCG, the human chorionic gonadotrophin is an important hormone, which is synthesized during pregnancy by syncytiotrophoblasts of the placenta. It is essentially required for the maintenance of pregnancy and reaches very high concentrations in the blood. Like pituitary glycoprotein hormones it consists of an alpha and a beta chain. Alpha chains of these hormones are almost identical in structure and aa sequences, while beta chains have more different aa sequences. Beta chains seem to be responsible for the different hormone-specific activities. The single chains have no known biological activity, but they are exprimed and secreted in reasonable amounts by some neoblastic tissues.

Immunogen :

Purified human chorionic gonadotrophin

Specificity :

HCG and ß-HCG, cross-reaction with alpha-HCG 0%, hLH 0,3%, hTSH 0,02%, hFSH 0,01%

Application Summary :

IHC(P), possible other applications like ELISA and RIA not tested in our laboratory

Storage :

2-8°C

General References :

1. Morrish D.W. Marusyk H., and Siy O. (1987) Demonstration of specific secretory granules for human chorionic gonadotrophin in placenta. J. Histochem Cytochem. 35; 93-101.

Product References :

2. Templ H., Kuzmits R., and Kratzik Ch. (1987) Increased microsomal aromatase activity in choriocarcinoma compared to embryonal carcinoma in testicular tumour tissue. J. Steroid Biochem. 28, Suppl.; Abstract B-043, p.69S.