Collagen Type VII, human | BioLogo COL007 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

BioLogo

product type :

antibody

product name :

Collagen Type VII, human

catalog :

COL007

quantity :

1 ml

price :

330 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

LH7.2

reactivity :

human, cow

application :

immunohistochemistry, immunocytochemistry

citations: 1

Published Application/Species/Sample/Dilution	Reference
immunocytochemistry; human; 1:10	Pautke C, Schieker M, Tischer T, Kolk A, Neth P, Mutschler W, et al. Characterization of osteosarcoma cell lines MG-63, Saos-2 and U-2 OS in comparison to human osteoblasts. Anticancer Res. 2004;24:3743-8 pubmed

product information

Catalog Number :

COL007

Product Name :

Collagen Type VII, human

Host Species :

Mouse

Product Type :

Primary Antibody

Size :

1 ml

List Price :

330 USD

Clone :

LH7.2

Isotype :

IgG1

CrossReactivity :

Human, Marmoset, Monkey, Cow, Sheep, Goat, and Guinea pig

Background :

Collagens consist of a family of highly specialized glycoproteins of which at least 16 genetically distinct types are known to date. The basal unit of a collagen molecule consists of a triple-helical structure formed by 3 alpha-chains. Predominant amino acids are glycine, proline and hydroxproline. Regularly also lysines and hydroxylysines occur, which are responsible for cross-linkage and glycosylation of the protein chains. Different composition of alpha-chains and different glycosylation contribute to the high variability of collagens in different tissues and organs.

Immunogen :

Extract of human neonatal foreskin

Specificity :

Collagen type VII, carboxyterminal

Concentration :

50 µg/ml

Application Summary :

IHC(C), IFA

Storage :

2-8°C

General References :

1. Hegerty A.M.H., et al. (1986) Identification of an epidermal basement membrane defect in recessive forms of dystrophic epidermolysis bullosa by LH7.2 monoclonal antibody: use in diagnosis. Br. J. Dermatol. 115; 125-131.

Product References :

2. Leigh IM, Eady RA, Heagerty AH, Purkis PE, Whitehead PA, Burgeson RE (1988) Type VII collagen is a normal component of epidermal basement membrane, which shows altered expression in recessive dystrophic epidermolysis bullosa. J Invest Dermatol. 90(5):