C-erbB-2 Onkoprotein, HER-2/neu | BioLogo CE110-G product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

BioLogo

product type :

antibody

product name :

C-erbB-2 Onkoprotein, HER-2/neu

catalog :

CE110-G

quantity :

5 ml

price :

150 USD

clonality :

monoclonal

host :

rabbit

conjugate :

nonconjugated

clone name :

ZR5

reactivity :

human

application :

immunohistochemistry

product information

Catalog Number :

CE110-G

Product Name :

C-erbB-2 Onkoprotein, HER-2/neu

Host Species :

Rabbit

Product Type :

Primary Antibody

Size :

5 ml

List Price :

150 USD

Clone :

ZR5

Isotype :

IgG

CrossReactivity :

Human

Background :

C-erbB-2 proto-oncogene is localized on human chromosome 17 encoding for a 185-190 kDa membrane protein, showing structural similarity to the EGF-receptor. Over-expression of c-erbB-2 oncoprotein is correlated with bad prognosis in mamma carcinoma. Also other carcinoma like adenocarcinoma of the stomach exhibit increased levels of C-erb B-2 gene product. Synonyms for c-erbB-2 oncoprotein are ERBB2 oncoprotein, neu-oncoprotein, and HER-2/neu oncoprotein.

Immunogen :

Recombinant protein according to the extracellular domain of the c-erbB2 molecule

Specificity :

C-erbB-2 oncoprotein

Application Summary :

IHC(C, P)

Storage :

2-8°C

General References :

1. Van de Vijver M. J., et al. (1988) Immunohistochemical detection of the neu-protein in tissue sections of human breast tumours with amplified neu-DNA. Oncogene 2; 175-178.

Product References :

2. Flack V.G. et al., et al. (1989) C-erb B-2 oncogene product staining in gastric adenocarcinoma. An immunohistochemical study. J. Pathol. 159; 107-111.