Alpha-Actin, sarcomeric | BioLogo AA105 product information

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product summary

company name :

BioLogo

product type :

antibody

product name :

Alpha-Actin, sarcomeric

catalog :

AA105

quantity :

1 ml

price :

220 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

5C5

reactivity :

human, rat, cow

application :

immunohistochemistry

product information

Catalog Number :

AA105

Product Name :

Alpha-Actin, sarcomeric

Host Species :

Mouse

Product Type :

Primary Antibody

Size :

1 ml

List Price :

220 USD

Clone :

5C5

Isotype :

IgM

CrossReactivity :

Human, amphibia, bony fish, cattle, guinea pig, reptiles, rabbit, rat, sheep

Background :

Movement of cell organelles, cells, and organisms depends on the interaction of the cytoskeletal proteins actin and myosin. In birds and mammals up to now six different isoforms of actin have been identified using amino acid sequence analysis and electrophoresis. They are more or less specific for different organs resp. cell types. Four isoforms are known to occur in muscle cells, while two other forms are found in most other cell types.

Immunogen :

Purified rabbit skeletal muscle actin

Specificity :

Alpha-Actin sarcomeric (a-sr-1) specific for skeletal- and heart-muscle

Application Summary :

IHC(C, P)

Storage :

2-8°C

General References :

1. Skalli O, Gabbiani G, Babai F, Seemayer TA, Pizzolato G, Schurch W. Intermediate filament proteins and actin isoforms as markers for soft tissue tumor differentiation and origin. II. Rhabdomyosarcomas. Am. J. Pathol., 130; 515ff (1988)

Product References :

2. Babai F, Skalli O, Schurch W, Seemayer TA, Gabbiani G. Chemically induced rhabdomyosarcomas in rats. Ultrastructural, immunohistochemical, biochemical features and expression of alpha-actin isoforms. Virchows Arch B Cell Pathol Incl Mol Pathol. 1988;55(5):263-77.