Alpha-Actin, smooth muscle | BioLogo AA100 product information

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product summary

company name :

BioLogo

product type :

antibody

product name :

Alpha-Actin, smooth muscle

catalog :

AA100

quantity :

1 ml

price :

225 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

1A4

reactivity :

human

application :

western blot, immunohistochemistry, immunohistochemistry - paraffin section

citations: 1

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry - paraffin section; human; 1:200	Sellheyer K, Krahl D. Spatiotemporal expression pattern of neuroepithelial stem cell marker nestin suggests a role in dermal homeostasis, neovasculogenesis, and tumor stroma development: a study on embryonic and adult human skin. J Am Acad Dermatol. 2010;63:93-113 pubmed publisher

product information

Catalog Number :

AA100

Product Name :

Alpha-Actin, smooth muscle

Host Species :

Mouse

Product Type :

Primary Antibody

Size :

1 ml

List Price :

225 USD

Clone :

1A4

Isotype :

IgG2a

CrossReactivity :

Human and other vertebrates

Background :

Movement of cell organelles, cells, and organisms depends on the interaction of the cytoskeletal proteins actin and myosin. In birds and mammals up to now six different isoforms of actin have been identified using amino acid sequence analysis and electrophoresis. They are more or less specific for different organs resp. cell types. Four isoforms are known to occur in muscle cells, while two other forms are found in most other cell types.

Immunogen :

Synthetic N-terminal decapeptide of smooth muscle Alpha-Actin

Specificity :

Alpha-Actin, smooth muscle

Application Summary :

IHC(C, P), WB

Storage :

2-8°C

General References :

1. Skalli O, Ropraz P., Trzeciak A., Benzonana G., Gillessen D. Gabbiani G. (1986) A monoclonal antibody against alpha-smooth muscle actin: a new probe for smooth muscle differentiation. J. Cell Biol. 103; 2787-2796

Product References :

2. Skalli O., Schürch W., Seemayer T., Lagacé R., Montandon D., Pittet B., et al. (1989) Myofibroblasts from diverse pathologic settings are heterogenous in their content of actin isoforms and intermediate filament proteins. Lab Invest. 60; 275-285