APC/Fire™ 750 anti-human HLA-DR | BioLegend 980412 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

APC/Fire™ 750 anti-human HLA-DR

catalog :

980412

quantity :

500 μL

price :

370 USD

clonality :

monoclonal

host :

mouse

conjugate :

APC

clone name :

L243

reactivity :

human, mouse

application :

flow cytometry

more info or order :

BioLegend product webpage

citations: 2

Published Application/Species/Sample/Dilution	Reference
flow cytometry; mouse; loading ...; fig 3b	Poncette L, Chen X, Lorenz F, Blankenstein T. Effective NY-ESO-1-specific MHC II-restricted T cell receptors from antigen-negative hosts enhance tumor regression. J Clin Invest. 2019;129:324-335 pubmed publisher
	Gruber C, Patel R, Trachtman R, Lepow L, Amanat F, Krammer F, et al. Mapping Systemic Inflammation and Antibody Responses in Multisystem Inflammatory Syndrome in Children (MIS-C). Cell. 2020;183:982-995.e14 pubmed publisher

product information

Antigen :

HLA-DR

Apps. Abbrev. :

Cat # :

980412

Clone :

L243

Item :

APC/Fire™ 750 anti-human HLA-DR

Isotype :

Mouse IgG2a, κ

Other Names :

Major Histocompatibility Class II, MHC class II

Size :

500 μL

Price (USD) :

370 USD

Reactivity :

Human

Clonality :

Monoclonal

Host :

Mouse

Conjugate/Tag/Label :

APC_F750

Application Notes :

The L243 monoclonal antibody reacts with the HLA-DR antigen, a member of MHC class II molecules. It does not cross react with HLA-DP and HLA-DQ. Clone L243 binds a conformational epitope on HLA-DRa which depends on the correct folding of the aß heterodimer.^19Additional reported applications (for the relevant formats) include: immunoprecipitation^8, Western blotting^8, in vitro blocking of mixed lymphocyte reactions^9,10, depeletion of MHC class II cells^7, and immunohistochemical staining of acetone-fixed frozen sections^4,5. For sensitive functional assays, we recommend using the Ultra-LEAF™ purified antibody (Cat. No. 307648).;

more info or order :

BioLegend product webpage