Anti-Insulin Degrading Enzyme (IDE) | BioLegend 921201 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

Anti-Insulin Degrading Enzyme (IDE)

catalog :

921201

quantity :

100 μL

price :

241 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

9B12.225

reactivity :

human, mouse, rat

application :

western blot, immunocytochemistry, immunoprecipitation

citations: 15

Reference
Mikedis M, Fan Y, Nicholls P, Endo T, Jackson E, Cobb S, et al. DAZL mediates a broad translational program regulating expansion and differentiation of spermatogonial progenitors. elife. 2020;9: pubmed publisher
Mehnert M, Ciuffa R, Frommelt F, Uliana F, van Drogen A, Ruminski K, et al. Multi-layered proteomic analyses decode compositional and functional effects of cancer mutations on kinase complexes. Nat Commun. 2020;11:3563 pubmed publisher
Sinnamon J, Kim S, Fisk J, Song Z, Nakai H, Jeng S, et al. In Vivo Repair of a Protein Underlying a Neurological Disorder by Programmable RNA Editing. Cell Rep. 2020;32:107878 pubmed publisher
Zhang F, Bieniasz P. HIV-1 Vpr induces cell cycle arrest and enhances viral gene expression by depleting CCDC137. elife. 2020;9: pubmed publisher
Bensimon A, Pizzagalli M, Kartnig F, Dvorak V, Essletzbichler P, Winter G, et al. Targeted Degradation of SLC Transporters Reveals Amenability of Multi-Pass Transmembrane Proteins to Ligand-Induced Proteolysis. Cell Chem Biol. 2020;27:728-739.e9 pubmed publisher
Ripamonti S, Shomroni O, Rhee J, Chowdhury K, Jahn O, Hellmann K, et al. SUMOylation controls the neurodevelopmental function of the transcription factor Zbtb20. J Neurochem. 2020;: pubmed publisher
Ortega J, Daley E, Kour S, Samani M, Tellez L, Smith H, et al. Nucleocytoplasmic Proteomic Analysis Uncovers eRF1 and Nonsense-Mediated Decay as Modifiers of ALS/FTD C9orf72 Toxicity. Neuron. 2020;106:90-107.e13 pubmed publisher
Chronopoulos A, Thorpe S, Cortés E, Lachowski D, Rice A, Mykuliak V, et al. Syndecan-4 tunes cell mechanics by activating the kindlin-integrin-RhoA pathway. Nat Mater. 2020;19:669-678 pubmed publisher
Zheng B, Zhang J, Zheng T, Wang H, Li Z, Huan C, et al. ATP1B3 cooperates with BST-2 to promote hepatitis B virus restriction. J Med Virol. 2020;92:201-209 pubmed publisher
Hajicek N, Keith N, Siraliev Perez E, Temple B, Huang W, Zhang Q, et al. Structural basis for the activation of PLC-γ isozymes by phosphorylation and cancer-associated mutations. elife. 2019;8: pubmed publisher
Liu S, Wang S, Zou L, Li J, Song C, Chen J, et al. TMC1 is an essential component of a leak channel that modulates tonotopy and excitability of auditory hair cells in mice. elife. 2019;8: pubmed publisher
Carreras Sureda A, Jaña F, Urra H, Durand S, Mortenson D, Sagredo A, et al. Non-canonical function of IRE1α determines mitochondria-associated endoplasmic reticulum composition to control calcium transfer and bioenergetics. Nat Cell Biol. 2019;: pubmed publisher
Carty M, Kearney J, Shanahan K, Hams E, Sugisawa R, Connolly D, et al. Cell Survival and Cytokine Release after Inflammasome Activation Is Regulated by the Toll-IL-1R Protein SARM. Immunity. 2019;50:1412-1424.e6 pubmed publisher
English E, Mahn S, Marchese A. Endocytosis is required for CXC chemokine receptor type 4 (CXCR4)-mediated Akt activation and antiapoptotic signaling. J Biol Chem. 2018;293:11470-11480 pubmed publisher
Chou Y, Kuo W, Rosner M, Tang W, Goldman R. Structural changes in intermediate filament networks alter the activity of insulin-degrading enzyme. FASEB J. 2009;23:3734-42 pubmed publisher

product information

Antigen :

Insulin Degrading Enzyme

Apps. Abbrev. :

Western Blotting, ICC, IP

Cat # :

921201

Clone :

9B12.225

Item :

Anti-Insulin Degrading Enzyme (IDE)

Isotype :

Mouse IgG1, κ

Other Names :

INSULYSIN, Insulin-degrading enzyme, insulinase, insulin protease, Abeta-degrading protease

Size :

100 μL

Price (USD) :

241 USD

Reactivity :

Human, Mouse, Rat

Clonality :

Monoclonal

Host :

Mouse

Conjugate/Tag/Label :

ASCITES

Immunogen :

This antibody was raised against purified human erythrocyte IDE.

Application Notes :

This antibody only recognizes isoform 1 at approx. 118 kD, and does not recognize isoform 2 at approx. 54 kD. This antibody is effective in immunoblotting, immunofluorescence (IF), and immunoprecipitation (IP). *Predicted MW = about 118 kD (isoform 1), about 54kD (isoform 2) This antibody does not react with mouse.