product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
Purified anti-Mouse Keratin 6A
catalog :
905701
quantity :
100 μL
price :
288 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
Poly19057
reactivity :
mouse
application :
western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
citations: 39
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - paraffin section; mouse; 1:1000; loading ...; fig 1c
Schünke H, Göbel U, Dikic I, Pasparakis M. OTULIN inhibits RIPK1-mediated keratinocyte necroptosis to prevent skin inflammation in mice. Nat Commun. 2021;12:5912 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:1000; loading ...; fig 1e
Hoste E, Lecomte K, Annusver K, Vandamme N, Roels J, Maschalidi S, et al. OTULIN maintains skin homeostasis by controlling keratinocyte death and stem cell identity. Nat Commun. 2021;12:5913 pubmed publisher
  • immunocytochemistry; mouse; loading ...; fig s1b
Rogerson C, Gissen P. VPS33B and VIPAR are essential for epidermal lamellar body biogenesis and function. Biochim Biophys Acta Mol Basis Dis. 2018;1864:1609-1621 pubmed publisher
  • immunohistochemistry; mouse; loading ...; fig 2e
Kousa Y, Roushangar R, Patel N, Walter A, Marangoni P, Krumlauf R, et al. IRF6 and SPRY4 Signaling Interact in Periderm Development. J Dent Res. 2017;96:1306-1313 pubmed publisher
  • immunohistochemistry; mouse; loading ...; fig 2b
Shatirishvili M, Burk A, Franz C, Pace G, Kastilan T, Breuhahn K, et al. Epidermal-specific deletion of CD44 reveals a function in keratinocytes in response to mechanical stress. Cell Death Dis. 2016;7:e2461 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:50; loading ...; fig 2B
Marichal T, Gaudenzio N, El Abbas S, Sibilano R, Zurek O, Starkl P, et al. Guanine nucleotide exchange factor RABGEF1 regulates keratinocyte-intrinsic signaling to maintain skin homeostasis. J Clin Invest. 2016;126:4497-4515 pubmed publisher
  • immunohistochemistry; mouse; fig 1
Lin J, Kumari S, Kim C, Van T, Wachsmuth L, Polykratis A, et al. RIPK1 counteracts ZBP1-mediated necroptosis to inhibit inflammation. Nature. 2016;540:124-128 pubmed publisher
  • immunohistochemistry - frozen section; mouse; loading ...; fig 6e
Altmeier S, Toska A, Sparber F, Teijeira A, Halin C, LeibundGut Landmann S. IL-1 Coordinates the Neutrophil Response to C. albicans in the Oral Mucosa. PLoS Pathog. 2016;12:e1005882 pubmed publisher
  • immunohistochemistry; mouse; loading ...; fig 3g
Yasuda T, Fukada T, Nishida K, Nakayama M, Matsuda M, Miura I, et al. Hyperactivation of JAK1 tyrosine kinase induces stepwise, progressive pruritic dermatitis. J Clin Invest. 2016;126:2064-76 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; loading ...; fig 1b
Holloway K, Sinha V, Bu W, Toneff M, Dong J, Peng Y, et al. Targeting Oncogenes into a Defined Subset of Mammary Cells Demonstrates That the Initiating Oncogenic Mutation Defines the Resulting Tumor Phenotype. Int J Biol Sci. 2016;12:381-8 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 2 ug/ml; fig 3
Crompton R, Williams H, Ansell D, Campbell L, Holden K, Cruickshank S, et al. Oestrogen promotes healing in a bacterial LPS model of delayed cutaneous wound repair. Lab Invest. 2016;96:439-49 pubmed publisher
Altshuler A, Amitai Lange A, Tarazi N, Dey S, Strinkovsky L, Hadad Porat S, et al. Discrete limbal epithelial stem cell populations mediate corneal homeostasis and wound healing. Cell Stem Cell. 2021;28:1248-1261.e8 pubmed publisher
Bornes L, Windoffer R, Leube R, Morgner J, van Rheenen J. Scratch-induced partial skin wounds re-epithelialize by sheets of independently migrating keratinocytes. Life Sci Alliance. 2021;4: pubmed publisher
Cottle D, Ursino G, Jones L, Tham M, Zylberberg A, Smyth I. Topical Aminosalicylic Acid Improves Keratinocyte Differentiation in an Inducible Mouse Model of Harlequin Ichthyosis. Cell Rep Med. 2020;1:100129 pubmed publisher
Seldin L, Macara I. DNA Damage Promotes Epithelial Hyperplasia and Fate Mis-specification via Fibroblast Inflammasome Activation. Dev Cell. 2020;55:558-573.e6 pubmed publisher
Kim C, Ding X, Allmeroth K, Biggs L, Kolenc O, L Hoest N, et al. Glutamine Metabolism Controls Stem Cell Fate Reversibility and Long-Term Maintenance in the Hair Follicle. Cell Metab. 2020;32:629-642.e8 pubmed publisher
Xu K, Huang Y, Liu X, Zhang M, Xie H. Organotypic Culture of Mouse Meibomian Gland: A Novel Model to Study Meibomian Gland Dysfunction In Vitro. Invest Ophthalmol Vis Sci. 2020;61:30 pubmed publisher
Jiao H, Wachsmuth L, Kumari S, Schwarzer R, Lin J, Eren R, et al. Z-nucleic-acid sensing triggers ZBP1-dependent necroptosis and inflammation. Nature. 2020;580:391-395 pubmed publisher
Laurien L, Nagata M, Schünke H, Delanghe T, Wiederstein J, Kumari S, et al. Autophosphorylation at serine 166 regulates RIP kinase 1-mediated cell death and inflammation. Nat Commun. 2020;11:1747 pubmed publisher
Kashgari G, Meinecke L, Gordon W, Ruiz B, Yang J, Ma A, et al. Epithelial Migration and Non-adhesive Periderm Are Required for Digit Separation during Mammalian Development. Dev Cell. 2020;52:764-778.e4 pubmed publisher
Jee J, Pangeni R, Jha S, Byun Y, Park J. Preparation and in vivo evaluation of a topical hydrogel system incorporating highly skin-permeable growth factors, quercetin, and oxygen carriers for enhanced diabetic wound-healing therapy. Int J Nanomedicine. 2019;14:5449-5475 pubmed publisher
Norum J, Frings O, Kasper M, Bergholtz H, Zell Thime H, Bergström A, et al. GLI1-induced mammary gland tumours are transplantable and maintain major molecular features. Int J Cancer. 2020;146:1125-1138 pubmed publisher
Sarper S, Inubushi T, Kurosaka H, Ono Minagi H, Murata Y, Kuremoto K, et al. Anterior Cleft Palate due to Cbfb deficiency and its rescue by folic acid. Dis Model Mech. 2019;: pubmed publisher
Fang X, Ni N, Lydon J, Ivanov I, Bayless K, Rijnkels M, et al. Enhancer of Zeste 2 Polycomb Repressive Complex 2 Subunit Is Required for Uterine Epithelial Integrity. Am J Pathol. 2019;189:1212-1225 pubmed publisher
Xu M, Lv J, Wang P, Liao Y, Li Y, Zhao W, et al. Vascular endothelial Cdc42 deficiency delays skin wound-healing processes by increasing IL-1β and TNF-α expression. Am J Transl Res. 2019;11:257-268 pubmed
Badolati N, Sommella E, Riccio G, Salviati E, Heintz D, Bottone S, et al. Annurca Apple Polyphenols Ignite Keratin Production in Hair Follicles by Inhibiting the Pentose Phosphate Pathway and Amino Acid Oxidation. Nutrients. 2018;10: pubmed publisher
Anderton H, Bandala Sanchez E, Simpson D, Rickard J, Ng A, Di Rago L, et al. RIPK1 prevents TRADD-driven, but TNFR1 independent, apoptosis during development. Cell Death Differ. 2019;26:877-889 pubmed publisher
Avigad Laron E, Aamar E, Enshell Seijffers D. The Mesenchymal Niche of the Hair Follicle Induces Regeneration by Releasing Primed Progenitors from Inhibitory Effects of Quiescent Stem Cells. Cell Rep. 2018;24:909-921.e3 pubmed publisher
Seong J, Kim N, Kim J, Lee W, Seo J, Yum M, et al. Side branching and luminal lineage commitment by ID2 in developing mammary glands. Development. 2018;145: pubmed publisher
Whiteley J, Chow T, Adissu H, Keating A, Rogers I. Topical Application of Culture-Expanded CD34+ Umbilical Cord Blood Cells from Frozen Units Accelerates Healing of Diabetic Skin Wounds in Mice. Stem Cells Transl Med. 2018;7:591-601 pubmed publisher
Dedeic Z, Sutendra G, Hu Y, Chung K, Slee E, White M, et al. Cell autonomous role of iASPP deficiency in causing cardiocutaneous disorders. Cell Death Differ. 2018;25:1289-1303 pubmed publisher
Anderton H, Rickard J, Varigos G, Lalaoui N, Silke J. Inhibitor of Apoptosis Proteins (IAPs) Limit RIPK1-Mediated Skin Inflammation. J Invest Dermatol. 2017;137:2371-2379 pubmed publisher
Kousa Y, Moussa D, Schutte B. IRF6 expression in basal epithelium partially rescues Irf6 knockout mice. Dev Dyn. 2017;246:670-681 pubmed publisher
Carceller E, Ballegeer M, Deckers J, Riccardi C, Bruscoli S, Hochepied T, et al. Overexpression of Glucocorticoid-induced Leucine Zipper (GILZ) increases susceptibility to Imiquimod-induced psoriasis and involves cutaneous activation of TGF-?1. Sci Rep. 2016;6:38825 pubmed publisher
Buonanno M, Stanislauskas M, Ponnaiya B, Bigelow A, Randers Pehrson G, Xu Y, et al. 207-nm UV Light-A Promising Tool for Safe Low-Cost Reduction of Surgical Site Infections. II: In-Vivo Safety Studies. PLoS ONE. 2016;11:e0138418 pubmed publisher
Alrefai H, Muhammad K, Rudolf R, Pham D, Klein Hessling S, Patra A, et al. NFATc1 supports imiquimod-induced skin inflammation by suppressing IL-10 synthesis in B cells. Nat Commun. 2016;7:11724 pubmed publisher
Turpin J, Ling C, Crosby E, Hartman Z, Simond A, Chodosh L, et al. The ErbB2ΔEx16 splice variant is a major oncogenic driver in breast cancer that promotes a pro-metastatic tumor microenvironment. Oncogene. 2016;35:6053-6064 pubmed publisher
Coelho P, Bury L, Shahbazi M, Liakath Ali K, Tate P, Wormald S, et al. Over-expression of Plk4 induces centrosome amplification, loss of primary cilia and associated tissue hyperplasia in the mouse. Open Biol. 2015;5:150209 pubmed publisher
Chen S, Shi J, Zhang M, Chen Y, Wang X, Zhang L, et al. Mesenchymal stem cell-laden anti-inflammatory hydrogel enhances diabetic wound healing. Sci Rep. 2015;5:18104 pubmed publisher
product information
Antigen :
Keratin 6A
Apps. Abbrev. :
IHC-P, Western Blotting
Cat # :
905701
Clone :
Poly19057
Item :
Purified anti-Mouse Keratin 6A
Isotype :
Rabbit Polyclonal IgG
Other Names :
Keratin, type II cytoskeletal 6A, K6A, CK-6A, mK6-alpha, keratin-6A, 60-kD keratin, cytokeratin-6A, keratin-6-alpha
Size :
100 μL
Price (USD) :
288 USD
Reactivity :
Mouse
Clonality :
Polyclonal
Host :
Rabbit
Conjugate/Tag/Label :
PURE
Immunogen :
This monospecific polyclonal antibody was raised against a peptide sequence derived from the C-terminus of the mouse keratin 6 protein.
Application Notes :
This antibody is effective in immunoblotting (WB), immunofluorescence (IF) and immunohistochemistry (IHC). This antibody has been successfully used in both frozen and paraffin embedded tissues. *Predicted MW = 59.9 kD . This product may contain other non-IgG subtypes.
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA