This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
Purified Loricrin pAb
catalog :
905101
quantity :
100 μL
price :
374 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
Poly19051
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section, other
citations: 31
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - frozen section; mouse; 1:2000; loading ...; fig 4s1c
Laurin M, Gomez N, Levorse J, Sendoel A, Sribour M, Fuchs E. An RNAi screen unravels the complexities of Rho GTPase networks in skin morphogenesis. elife. 2019;8: pubmed publisher
  • immunohistochemistry - paraffin section; mouse; loading ...; fig 3d
  • western blot; mouse; loading ...; fig 3e
Young C, Eckert R, Adhikary G, Crumrine D, Elias P, Blumenberg M, et al. Embryonic AP1 Transcription Factor Deficiency Causes a Collodion Baby-Like Phenotype. J Invest Dermatol. 2017;137:1868-1877 pubmed publisher
  • other; mouse; 1:200; loading ...; fig 3a
  • western blot; mouse; 1:1000; loading ...; fig 3b
Shin J, Choi D, Sohn K, Kim J, Im M, Lee Y, et al. Targeted deletion of Crif1 in mouse epidermis impairs skin homeostasis and hair morphogenesis. Sci Rep. 2017;7:44828 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 2c
Naeem A, Tommasi C, Cole C, Brown S, Zhu Y, Way B, et al. A mechanistic target of rapamycin complex 1/2 (mTORC1)/V-Akt murine thymoma viral oncogene homolog 1 (AKT1)/cathepsin H axis controls filaggrin expression and processing in skin, a novel mechanism for skin barrier disruption in patients with atopic d. J Allergy Clin Immunol. 2017;139:1228-1241 pubmed publisher
  • immunohistochemistry; mouse; loading ...; fig 3b
Shatirishvili M, Burk A, Franz C, Pace G, Kastilan T, Breuhahn K, et al. Epidermal-specific deletion of CD44 reveals a function in keratinocytes in response to mechanical stress. Cell Death Dis. 2016;7:e2461 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:50; loading ...; fig S5B
Marichal T, Gaudenzio N, El Abbas S, Sibilano R, Zurek O, Starkl P, et al. Guanine nucleotide exchange factor RABGEF1 regulates keratinocyte-intrinsic signaling to maintain skin homeostasis. J Clin Invest. 2016;126:4497-4515 pubmed publisher
  • immunohistochemistry; human; 1:2000; fig 1a
Niehues H, Schalkwijk J, van Vlijmen Willems I, Rodijk Olthuis D, van Rossum M, Wladykowski E, et al. Epidermal equivalents of filaggrin null keratinocytes do not show impaired skin barrier function. J Allergy Clin Immunol. 2017;139:1979-1981.e13 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:250; fig 4C
Iacovides D, Rizki G, Lapathitis G, Strati K. Direct conversion of mouse embryonic fibroblasts into functional keratinocytes through transient expression of pluripotency-related genes. Stem Cell Res Ther. 2016;7:98 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:1000; fig 1
Mardaryev A, Liu B, Rapisarda V, Poterlowicz K, Malashchuk I, Rudolf J, et al. Cbx4 maintains the epithelial lineage identity and cell proliferation in the developing stratified epithelium. J Cell Biol. 2016;212:77-89 pubmed publisher
Yuan Y, Park J, Feng A, Awasthi P, Wang Z, Chen Q, et al. YAP1/TAZ-TEAD transcriptional networks maintain skin homeostasis by regulating cell proliferation and limiting KLF4 activity. Nat Commun. 2020;11:1472 pubmed publisher
Miao Q, Hill M, Chen F, Mo Q, Ku A, Ramos C, et al. SOX11 and SOX4 drive the reactivation of an embryonic gene program during murine wound repair. Nat Commun. 2019;10:4042 pubmed publisher
Han Y, Mora J, Huard A, da Silva P, Wiechmann S, Putyrski M, et al. IL-38 Ameliorates Skin Inflammation and Limits IL-17 Production from γδ T Cells. Cell Rep. 2019;27:835-846.e5 pubmed publisher
Lecland N, Hsu C, Chemin C, Merdes A, Bierkamp C. Epidermal development requires ninein for spindle orientation and cortical microtubule organization. Life Sci Alliance. 2019;2: pubmed publisher
Suzuki S, Nomura T, Miyauchi T, Takeda M, Fujita Y, Nishie W, et al. Somatic recombination underlies frequent revertant mosaicism in loricrin keratoderma. Life Sci Alliance. 2019;2: pubmed publisher
Li L, Wang Y, Torkelson J, Shankar G, Pattison J, Zhen H, et al. TFAP2C- and p63-Dependent Networks Sequentially Rearrange Chromatin Landscapes to Drive Human Epidermal Lineage Commitment. Cell Stem Cell. 2019;24:271-284.e8 pubmed publisher
Duchatelet S, Boyden L, Ishida Yamamoto A, Zhou J, Guibbal L, Hu R, et al. Mutations in PERP Cause Dominant and Recessive Keratoderma. J Invest Dermatol. 2019;139:380-390 pubmed publisher
Piao X, Miura R, Miyake S, Komazawa Sakon S, Koike M, Shindo R, et al. Blockade of TNF receptor superfamily 1 (TNFR1)-dependent and TNFR1-independent cell death is crucial for normal epidermal differentiation. J Allergy Clin Immunol. 2019;143:213-228.e10 pubmed publisher
Niehues H, Rösler B, van der Krieken D, van Vlijmen Willems I, Rodijk Olthuis D, Peppelman M, et al. STAT1 gain-of-function compromises skin host defense in the context of interferon-γ signaling. J Allergy Clin Immunol. 2018;: pubmed publisher
Qu J, Tanis S, Smits J, Kouwenhoven E, Oti M, van den Bogaard E, et al. Mutant p63 Affects Epidermal Cell Identity through Rewiring the Enhancer Landscape. Cell Rep. 2018;25:3490-3503.e4 pubmed publisher
Nishiguchi M, Spencer C, Leung D, Leung T. Aging Suppresses Skin-Derived Circulating SDF1 to Promote Full-Thickness Tissue Regeneration. Cell Rep. 2018;24:3383-3392.e5 pubmed publisher
Zhang Y, Yang Y, Jiang M, Huang S, Zhang W, Al Alam D, et al. 3D Modeling of Esophageal Development using Human PSC-Derived Basal Progenitors Reveals a Critical Role for Notch Signaling. Cell Stem Cell. 2018;23:516-529.e5 pubmed publisher
Tripurani S, Wang Y, Fan Y, Rahimi M, Wong L, Lee M, et al. Suppression of Wnt/β-catenin signaling by EGF receptor is required for hair follicle development. Mol Biol Cell. 2018;29:2784-2799 pubmed publisher
Vogl T, Stratis A, Wixler V, Voller T, Thurainayagam S, Jorch S, et al. Autoinhibitory regulation of S100A8/S100A9 alarmin activity locally restricts sterile inflammation. J Clin Invest. 2018;128:1852-1866 pubmed publisher
Boink M, Roffel S, Breetveld M, Thon M, Haasjes M, Waaijman T, et al. Comparison of advanced therapy medicinal product gingiva and skin substitutes and their in vitro wound healing potentials. J Tissue Eng Regen Med. 2018;12:e1088-e1097 pubmed publisher
Madon Simon M, Grad I, Bayo P, Perez P, Picard D. Defective glucocorticoid receptor signaling and keratinocyte-autonomous defects contribute to skin phenotype of mouse embryos lacking the Hsp90 co-chaperone p23. PLoS ONE. 2017;12:e0180035 pubmed publisher
Kousa Y, Moussa D, Schutte B. IRF6 expression in basal epithelium partially rescues Irf6 knockout mice. Dev Dyn. 2017;246:670-681 pubmed publisher
Carceller E, Ballegeer M, Deckers J, Riccardi C, Bruscoli S, Hochepied T, et al. Overexpression of Glucocorticoid-induced Leucine Zipper (GILZ) increases susceptibility to Imiquimod-induced psoriasis and involves cutaneous activation of TGF-?1. Sci Rep. 2016;6:38825 pubmed publisher
Devos M, Gilbert B, Denecker G, Leurs K, Mc Guire C, Lemeire K, et al. Elevated ΔNp63α Levels Facilitate Epidermal and Biliary Oncogenic Transformation. J Invest Dermatol. 2017;137:494-505 pubmed publisher
Matsui M, Tanaka K, Higashiguchi N, Okawa H, Yamada Y, Tanaka K, et al. Protective and therapeutic effects of fucoxanthin against sunburn caused by UV irradiation. J Pharmacol Sci. 2016;132:55-64 pubmed publisher
Dahlhoff M, Camera E, Schäfer M, Emrich D, Riethmacher D, Foster A, et al. Sebaceous lipids are essential for water repulsion, protection against UVB-induced apoptosis and ocular integrity in mice. Development. 2016;143:1823-31 pubmed publisher
Wu N, Huang D, Wang L, Kannagi R, Fan Y, Lin W. Spleen Tyrosine Kinase Mediates EGFR Signaling to Regulate Keratinocyte Terminal Differentiation. J Invest Dermatol. 2016;136:192-201 pubmed publisher
product information
Antigen :
Loricrin
Apps. Abbrev. :
IHC
Cat # :
905101
Clone :
Poly19051
Item :
Purified Loricrin pAb
Isotype :
Rabbit Polyclonal
Other Names :
Loricrin
Size :
100 μL
Price (USD) :
374 USD
Reactivity :
Human
Clonality :
Polyclonal
Host :
Rabbit
Conjugate/Tag/Label :
PURE
Immunogen :
This monospecific polyclonal antibody was raised against a peptide sequence derived from the C-terminus of the mouse loricrin protein. It was subsequently purified using peptide affinity chromatography.
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA