Anti-Fibrillarin | BioLegend 905001 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

Anti-Fibrillarin

catalog :

905001

quantity :

200 μL

price :

313 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

38F3

reactivity :

human, mouse, rat

application :

western blot, immunocytochemistry

citations: 5

Reference
Mars J, Tremblay M, Valere M, Sibai D, Sabourin Felix M, Lessard F, et al. The chemotherapeutic agent CX-5461 irreversibly blocks RNA polymerase I initiation and promoter release to cause nucleolar disruption, DNA damage and cell inviability. NAR Cancer. 2020;2:zcaa032 pubmed publisher
Herdman C, Mars J, Stefanovsky V, Tremblay M, Sabourin Felix M, Lindsay H, et al. A unique enhancer boundary complex on the mouse ribosomal RNA genes persists after loss of Rrn3 or UBF and the inactivation of RNA polymerase I transcription. PLoS Genet. 2017;13:e1006899 pubmed publisher
Scruggs B, Michel C, Ory D, Schaffer J. SmD3 regulates intronic noncoding RNA biogenesis. Mol Cell Biol. 2012;32:4092-103 pubmed
Lessard F, Stefanovsky V, Tremblay M, Moss T. The cellular abundance of the essential transcription termination factor TTF-I regulates ribosome biogenesis and is determined by MDM2 ubiquitinylation. Nucleic Acids Res. 2012;40:5357-67 pubmed publisher
Denissov S, Lessard F, Mayer C, Stefanovsky V, van Driel M, Grummt I, et al. A model for the topology of active ribosomal RNA genes. EMBO Rep. 2011;12:231-7 pubmed publisher

product information

Antigen :

Fibrillarin

Apps. Abbrev. :

WB, ICC, KO/KD-WB

Cat # :

905001

Clone :

38F3

Item :

Anti-Fibrillarin

Isotype :

Mouse IgG1

Other Names :

RRNA 2'-O-methyltransferase fibrillarin, 34 kD nucleolar scleroderma antigen, RNA, U3 small nucleolar interacting protein 1

Size :

200 μL

Price (USD) :

313 USD

Reactivity :

Human, Mouse, Rat, Drosophila

Clonality :

Monoclonal

Host :

Mouse

Conjugate/Tag/Label :

TCS

Immunogen :

38F3 was raised against yeast nuclear preparations.

Application Notes :

Reactivity to Drosophila was only verified with the purified format.This antibody is useful for immunoblotting (WB), immunofluorescence (ICC) and immunocytochemistry.*Predicted MW = 34 kD;