Purified anti-RNA Polymerase II | BioLegend 904001 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

Purified anti-RNA Polymerase II

catalog :

904001

quantity :

100 μL

price :

253 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

CTD4H8

reactivity :

human, mouse, rat

application :

western blot, immunocytochemistry

more info or order :

BioLegend product webpage

citations: 20

Published Application/Species/Sample/Dilution	Reference
western blot; human; loading ...; fig 5a	Rother S, Bartels M, Schweda A, Resch K, Pallua N, Nourbakhsh M. NF-ÎºB-repressing factor phosphorylation regulates transcription elongation via its interactions with 5'â†’3' exoribonuclease 2 and negative elongation factor. FASEB J. 2016;30:174-85 pubmed publisher
	Endres T, Solvie D, Heidelberger J, Andrioletti V, Baluapuri A, Ade C, et al. Ubiquitylation of MYC couples transcription elongation with double-strand break repair at active promoters. Mol Cell. 2021;: pubmed publisher
	Yao H, Hannum D, Zhai Y, Hill S, Albanus R, Lou W, et al. CHD7 promotes neural progenitor differentiation in embryonic stem cells via altered chromatin accessibility and nascent gene expression. Sci Rep. 2020;10:17445 pubmed publisher
	Hasenpusch Theil K, Laclef C, Colligan M, Fitzgerald E, Howe K, Carroll E, et al. A transient role of the ciliary gene Inpp5e in controlling direct versus indirect neurogenesis in cortical development. elife. 2020;9: pubmed publisher
	Yan P, Liu Z, Song M, Wu Z, Xu W, Li K, et al. Genome-wide R-loop Landscapes during Cell Differentiation and Reprogramming. Cell Rep. 2020;32:107870 pubmed publisher
	Roy A, Millen K, Kapur R. Hippocampal granule cell dispersion: a non-specific finding in pediatric patients with no history of seizures. Acta Neuropathol Commun. 2020;8:54 pubmed publisher
	Selvadurai H, Luis E, Desai K, Lan X, Vladoiu M, Whitley O, et al. Medulloblastoma Arises from the Persistence of a Rare and Transient Sox2+ Granule Neuron Precursor. Cell Rep. 2020;31:107511 pubmed publisher
	Shao W, Yang J, He M, Yu X, Lee C, Yang Z, et al. Centrosome anchoring regulates progenitor properties and cortical formation. Nature. 2020;580:106-112 pubmed publisher
	Cossa G, Roeschert I, Prinz F, Baluapuri A, Silveira Vidal R, Sch lein V lk C, et al. Localized Inhibition of Protein Phosphatase 1 by NUAK1 Promotes Spliceosome Activity and Reveals a MYC-Sensitive Feedback Control of Transcription. Mol Cell. 2020;: pubmed publisher
	Tomita H, Cornejo F, Aranda Pino B, Woodard C, Rioseco C, Neel B, et al. The Protein Tyrosine Phosphatase Receptor Delta Regulates Developmental Neurogenesis. Cell Rep. 2020;30:215-228.e5 pubmed publisher
	Bendriem R, Singh S, Aleem A, Antonetti D, Ross M. Tight junction protein occludin regulates progenitor Self-Renewal and survival in developing cortex. elife. 2019;8: pubmed publisher
	Ramme A, Faust D, Koenig L, Marx U. Generation of four integration-free iPSC lines from related human donors. Stem Cell Res. 2019;41:101615 pubmed publisher
	Singer R, Arnés L, Cui Y, Wang J, Gao Y, Guney M, et al. The Long Noncoding RNA Paupar Modulates PAX6 Regulatory Activities to Promote Alpha Cell Development and Function. Cell Metab. 2019;30:1091-1106.e8 pubmed publisher
	Lee E, Kim N, Park J, Kang K, Kim W, Sim N, et al. Global Analysis of Intercellular Homeodomain Protein Transfer. Cell Rep. 2019;28:712-722.e3 pubmed publisher
	Dey A, Yang W, Gegonne A, Nishiyama A, Pan R, Yagi R, et al. BRD4 directs hematopoietic stem cell development and modulates macrophage inflammatory responses. EMBO J. 2019;38: pubmed publisher
	Ono R, Masuya M, Ishii S, Katayama N, Nosaka T. Eya2, a Target Activated by Plzf, Is Critical for PLZF-RARA-Induced Leukemogenesis. Mol Cell Biol. 2017;37: pubmed publisher
	Bansal K, Yoshida H, Benoist C, Mathis D. The transcriptional regulator Aire binds to and activates super-enhancers. Nat Immunol. 2017;18:263-273 pubmed publisher
	Hong S, Choi K. Antagonistic roles of Drosophila Tctp and Brahma in chromatin remodelling and stabilizing repeated sequences. Nat Commun. 2016;7:12988 pubmed publisher
	CHAROS A, Reed B, Raha D, Szekely A, Weissman S, Snyder M. A highly integrated and complex PPARGC1A transcription factor binding network in HepG2 cells. Genome Res. 2012;22:1668-79 pubmed publisher
	Rafalska Metcalf I, Powers S, Joo L, LeRoy G, Janicki S. Single cell analysis of transcriptional activation dynamics. PLoS ONE. 2010;5:e10272 pubmed publisher

product information

Antigen :

RNA Polymerase II

Apps. Abbrev. :

Western Blotting, ICC

Cat # :

904001

Clone :

CTD4H8

Item :

Purified anti-RNA Polymerase II

Isotype :

Mouse IgG1, κ

Other Names :

DNA-directed RNA polymerase II subunit RPB1, RNA polymerase II subunit B1, DNA-directed RNA polymerase II subunit A, RNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase III largest subunit

Size :

100 μL

Price (USD) :

253 USD

Reactivity :

Human, Mouse, Rat

Clonality :

Monoclonal

Host :

Mouse

Conjugate/Tag/Label :

PURE

Immunogen :

The immunogen used was a peptide containing 10 repeats of the synthetic peptide YSPTSPS using chemically synthesized phospho-ser5.

Application Notes :

This antibody is effective in immunoblotting, immunoprecipitation and ELISA. It can also be used in chromatin immunoprecipitation assays. The antibody CTD4H8 recognizes the C-terminal repeat of the largest subunit of RNA polymerase II from HeLa and S. cerevisiae cells. This antibody recognizes both the phosphorylated and unphosphorylated forms of the RNA polymerase II. Based on sequence identify, this clone is liable to react with a broad range of species. Clone CTD4H8 is also known as 4H8 or CTD 4H8. . Predicted MW is about 217 kD, Observed MW is on WB gel is about 240 kD

more info or order :

BioLegend product webpage