product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
Purified anti-CD243/ABCB4 (ABCB1, P-glycoprotein1/MDR3)
catalog :
903701
quantity :
1 mL
price :
604 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
C219
reactivity :
human, mouse
application :
western blot, ELISA, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
citations: 9
Published Application/Species/Sample/DilutionReference
  • western blot; human
Huuskonen P, Myllynen P, Storvik M, Pasanen M. The effects of aflatoxin B1 on transporters and steroid metabolizing enzymes in JEG-3 cells. Toxicol Lett. 2013;218:200-6 pubmed publisher
  • western blot; human; 5 ug/ml
Liu Y, Han T, Giuliano A, Hansen N, Cabot M. Uncoupling ceramide glycosylation by transfection of glucosylceramide synthase antisense reverses adriamycin resistance. J Biol Chem. 2000;275:7138-43 pubmed
Giddings E, Champagne D, Wu M, Laffin J, Thornton T, Valença Pereira F, et al. Mitochondrial ATP fuels ABC transporter-mediated drug efflux in cancer chemoresistance. Nat Commun. 2021;12:2804 pubmed publisher
Song Y, Park J, Oh Y, Hyung S, Jeong Y, Kim M, et al. Suppression of Canine ATP Binding Cassette ABCB1 in Madin-Darby Canine Kidney Type II Cells Unmasks Human ABCG2-Mediated Efflux of Olaparib. J Pharmacol Exp Ther. 2019;368:79-87 pubmed publisher
Afrouzian M, Al Lahham R, Patrikeeva S, Xu M, Fokina V, Fischer W, et al. Role of the efflux transporters BCRP and MRP1 in human placental bio-disposition of pravastatin. Biochem Pharmacol. 2018;156:467-478 pubmed publisher
Kang S, Haydar G, Taniane C, Farrell G, Arias I, Lippincott Schwartz J, et al. AMPK Activation Prevents and Reverses Drug-Induced Mitochondrial and Hepatocyte Injury by Promoting Mitochondrial Fusion and Function. PLoS ONE. 2016;11:e0165638 pubmed publisher
Beck W, Grogan T, Willman C, Cordon Cardo C, Parham D, Kuttesch J, et al. Methods to detect P-glycoprotein-associated multidrug resistance in patients' tumors: consensus recommendations. Cancer Res. 1996;56:3010-20 pubmed
Lee J, Hughes C, Fine R, Page R. P-glycoprotein expression in canine lymphoma: a relevant, intermediate model of multidrug resistance. Cancer. 1996;77:1892-8 pubmed
Rao V, Anthony D, Piwnica Worms D. MDR1 gene-specific monoclonal antibody C494 cross-reacts with pyruvate carboxylase. Cancer Res. 1994;54:1536-41 pubmed
product information
Antigen :
CD243/ABCB4
Apps. Abbrev. :
IHC-P, Western Blotting, IHC-F, ICC, ELISA, Flow Cytometry
Cat # :
903701
Clone :
C219
Item :
Purified anti-CD243/ABCB4 (ABCB1, P-glycoprotein1/MDR3)
Isotype :
Mouse IgG1, κ
Other Names :
Multidrug resistance protein 3, P-glycoprotein 3, multiple drug resistance 3, ATP-binding cassette sub-family B member 4, P glycoprotein 3/multiple drug resistance 3
Size :
1 mL
Price (USD) :
604 USD
Reactivity :
Human, Mouse
Clonality :
Monoclonal
Host :
Mouse
Conjugate/Tag/Label :
PURE
Immunogen :
This antibody was made against SDS-solubilized plasma membranes of a multidrug resistant Chinese hamster ovary (CHO) cell line and a human cell line.
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA