| Reference |
|---|
Yan S, Conley J, Reilly A, Stull N, Abhyankar S, Ericsson A, et al. Intestinal Gpr17 deficiency improves glucose metabolism by promoting GLP-1 secretion. Cell Rep. 2022;38:110179 pubmed publisher |
Ohline S, Chan C, Schoderboeck L, Wicky H, Tate W, Hughes S, et al. Effect of soluble amyloid precursor protein-alpha on adult hippocampal neurogenesis in a mouse model of Alzheimer's disease. Mol Brain. 2022;15:5 pubmed publisher |
Zhu J, Li X, Cai X, Zha H, Zhou Z, Sun X, et al. Arginine monomethylation by PRMT7 controls MAVS-mediated antiviral innate immunity. Mol Cell. 2021;81:3171-3186.e8 pubmed publisher |
Buglino J, Sankhe G, Lazar N, Bean J, Glickman M. Integrated sensing of host stresses by inhibition of a cytoplasmic two-component system controls M. tuberculosis acute lung infection. elife. 2021;10: pubmed publisher |
Thrun A, Garzia A, Kigoshi Tansho Y, Patil P, Umbaugh C, Dallinger T, et al. Convergence of mammalian RQC and C-end rule proteolytic pathways via alanine tailing. Mol Cell. 2021;81:2112-2122.e7 pubmed publisher |
Jin S, Yoon N, Liu Z, Song J, Horvath T, Kim J, et al. Drp1 is required for AgRP neuronal activity and feeding. elife. 2021;10: pubmed publisher |
Huang T, Yang Y, Song X, Wan X, Wu B, Sastry N, et al. PRMT6 methylation of RCC1 regulates mitosis, tumorigenicity, and radiation response of glioblastoma stem cells. Mol Cell. 2021;81:1276-1291.e9 pubmed publisher |
Takakura M, Nakagawa R, Ota T, Kimura Y, Ng M, Alia A, et al. Rpd3/CoRest-mediated activity-dependent transcription regulates the flexibility in memory updating in Drosophila. Nat Commun. 2021;12:628 pubmed publisher |
Shen J, Qiu Z, Wu Q, Finlay D, Garcia G, Sun D, et al. FBXO44 promotes DNA replication-coupled repetitive element silencing in cancer cells. Cell. 2021;184:352-369.e23 pubmed publisher |
Groom S, Blum N, Conibear A, Disney A, Hill R, Husbands S, et al. A novel G protein-biased agonist at the μ opioid receptor induces substantial receptor desensitisation through G protein-coupled receptor kinase. Br J Pharmacol. 2020;: pubmed publisher |
Han J, Yu M, Bai Y, Yu J, Jin F, Li C, et al. Elevated CXorf67 Expression in PFA Ependymomas Suppresses DNA Repair and Sensitizes to PARP Inhibitors. Cancer Cell. 2020;38:844-856.e7 pubmed publisher |
Kreye J, Reincke S, Kornau H, Sánchez Sendin E, Corman V, Liu H, et al. A Therapeutic Non-self-reactive SARS-CoV-2 Antibody Protects from Lung Pathology in a COVID-19 Hamster Model. Cell. 2020;183:1058-1069.e19 pubmed publisher |
Huang W, Carr A, Hajicek N, Sokolovski M, Siraliev Perez E, Hardy P, et al. A High-Throughput Assay to Identify Allosteric Inhibitors of the PLC-γ Isozymes Operating at Membranes. Biochemistry. 2020;59:4029-4038 pubmed publisher |
Harding C, Sidik S, Petrova B, Gnädig N, Okombo J, Herneisen A, et al. Genetic screens reveal a central role for heme metabolism in artemisinin susceptibility. Nat Commun. 2020;11:4813 pubmed publisher |
Kong J, Young C, Pusapati G, Patel C, Ho S, Krishnan A, et al. A Membrane-Tethered Ubiquitination Pathway Regulates Hedgehog Signaling and Heart Development. Dev Cell. 2020;55:432-449.e12 pubmed publisher |
Offensperger F, Müller F, Jansen J, Hammler D, Götz K, Marx A, et al. Identification of Small-Molecule Activators of the Ubiquitin Ligase E6AP/UBE3A and Angelman Syndrome-Derived E6AP/UBE3A Variants. Cell Chem Biol. 2020;27:1510-1520.e6 pubmed publisher |
Gella A, Prada Dacasa P, Carrascal M, Urpi A, González Torres M, Abian J, et al. Mitochondrial Proteome of Affected Glutamatergic Neurons in a Mouse Model of Leigh Syndrome. Front Cell Dev Biol. 2020;8:660 pubmed publisher |
Karve K, Netherton S, Deng L, Bonni A, Bonni S. Regulation of epithelial-mesenchymal transition and organoid morphogenesis by a novel TGFβ-TCF7L2 isoform-specific signaling pathway. Cell Death Dis. 2020;11:704 pubmed publisher |
Akintayo A, Mayoral J, Asada M, Tang J, Sundaram S, Stanley P. Point mutations that inactivate MGAT4D-L, an inhibitor of MGAT1 and complex N-glycan synthesis. J Biol Chem. 2020;295:14053-14064 pubmed publisher |
Gatti M, Imhof R, Huang Q, Baudis M, Altmeyer M. The Ubiquitin Ligase TRIP12 Limits PARP1 Trapping and Constrains PARP Inhibitor Efficiency. Cell Rep. 2020;32:107985 pubmed publisher |
Zhuo Y, Gurevich V, Vishnivetskiy S, Klug C, Marchese A. A non-GPCR-binding partner interacts with a novel surface on β-arrestin1 to mediate GPCR signaling. J Biol Chem. 2020;295:14111-14124 pubmed publisher |
Mikedis M, Fan Y, Nicholls P, Endo T, Jackson E, Cobb S, et al. DAZL mediates a broad translational program regulating expansion and differentiation of spermatogonial progenitors. elife. 2020;9: pubmed publisher |
Mehnert M, Ciuffa R, Frommelt F, Uliana F, van Drogen A, Ruminski K, et al. Multi-layered proteomic analyses decode compositional and functional effects of cancer mutations on kinase complexes. Nat Commun. 2020;11:3563 pubmed publisher |
Sinnamon J, Kim S, Fisk J, Song Z, Nakai H, Jeng S, et al. In Vivo Repair of a Protein Underlying a Neurological Disorder by Programmable RNA Editing. Cell Rep. 2020;32:107878 pubmed publisher |
Higgins R, Kabbaj M, Sherwin D, Howell L, Hatcher A, Tomko R, et al. The Cdc48 Complex Alleviates the Cytotoxicity of Misfolded Proteins by Regulating Ubiquitin Homeostasis. Cell Rep. 2020;32:107898 pubmed publisher |
Sheetz J, Mathea S, Karvonen H, Malhotra K, Chatterjee D, Niininen W, et al. Structural Insights into Pseudokinase Domains of Receptor Tyrosine Kinases. Mol Cell. 2020;79:390-405.e7 pubmed publisher |
Wang H, Liu Y, Huan C, Yang J, Li Z, Zheng B, et al. NF-κB-Interacting Long Noncoding RNA Regulates HIV-1 Replication and Latency by Repressing NF-κB Signaling. J Virol. 2020;94: pubmed publisher |
Zhang F, Bieniasz P. HIV-1 Vpr induces cell cycle arrest and enhances viral gene expression by depleting CCDC137. elife. 2020;9: pubmed publisher |
Lazar A, Irannejad R, Baldwin T, Sundaram A, Gutkind J, Inoue A, et al. G protein-regulated endocytic trafficking of adenylyl cyclase type 9. elife. 2020;9: pubmed publisher |
Sapiro A, Freund E, Restrepo L, Qiao H, Bhate A, Li Q, et al. Zinc Finger RNA-Binding Protein Zn72D Regulates ADAR-Mediated RNA Editing in Neurons. Cell Rep. 2020;31:107654 pubmed publisher |
Liu Y, Wang H, Zhang J, Yang J, Bai L, Zheng B, et al. SERINC5 Inhibits the Secretion of Complete and Genome-Free Hepatitis B Virions Through Interfering With the Glycosylation of the HBV Envelope. Front Microbiol. 2020;11:697 pubmed publisher |
Flower T, Takahashi Y, Hudait A, Rose K, Tjahjono N, Pak A, et al. A helical assembly of human ESCRT-I scaffolds reverse-topology membrane scission. Nat Struct Mol Biol. 2020;27:570-580 pubmed publisher |
Ola M, O Brien C, Coughlan A, Ma Q, Donovan P, Wolfe K, et al. Polymorphic centromere locations in the pathogenic yeast Candida parapsilosis. Genome Res. 2020;30:684-696 pubmed publisher |
Dufey E, Bravo San Pedro J, Eggers C, González Quiroz M, Urra H, Sagredo A, et al. Genotoxic stress triggers the activation of IRE1α-dependent RNA decay to modulate the DNA damage response. Nat Commun. 2020;11:2401 pubmed publisher |
Duan H, Mansour S, Reed R, Gillis M, Parent B, Liu B, et al. E3 ligase RFWD3 is a novel modulator of stalled fork stability in BRCA2-deficient cells. J Cell Biol. 2020;219: pubmed publisher |
Bensimon A, Pizzagalli M, Kartnig F, Dvorak V, Essletzbichler P, Winter G, et al. Targeted Degradation of SLC Transporters Reveals Amenability of Multi-Pass Transmembrane Proteins to Ligand-Induced Proteolysis. Cell Chem Biol. 2020;27:728-739.e9 pubmed publisher |
Kim S, Forsburg S. Active Replication Checkpoint Drives Genome Instability in Fission Yeast mcm4 Mutant. Mol Cell Biol. 2020;40: pubmed publisher |
Murphy Royal C, Johnston A, Boyce A, Diaz Castro B, Institoris A, Peringod G, et al. Stress gates an astrocytic energy reservoir to impair synaptic plasticity. Nat Commun. 2020;11:2014 pubmed publisher |
Gavini C, Bonomo R, Mansuy Aubert V. Neuronal LXR Regulates Neuregulin 1 Expression and Sciatic Nerve-Associated Cell Signaling in Western Diet-fed Rodents. Sci Rep. 2020;10:6396 pubmed publisher |
Ripamonti S, Shomroni O, Rhee J, Chowdhury K, Jahn O, Hellmann K, et al. SUMOylation controls the neurodevelopmental function of the transcription factor Zbtb20. J Neurochem. 2020;: pubmed publisher |
Oguro A, Shigeta T, Machida K, Suzuki T, Iwamoto T, Matsufuji S, et al. Translation efficiency affects the sequence-independent +1 ribosomal frameshifting by polyamines. J Biochem. 2020;168:139-149 pubmed publisher |
Sanders T, Wenck B, Selan J, Barker M, Trimmer S, Walker J, et al. FttA is a CPSF73 homologue that terminates transcription in Archaea. Nat Microbiol. 2020;5:545-553 pubmed publisher |
Chen Y, Han H, Seo G, Vargas R, Yang B, Chuc K, et al. Systematic analysis of the Hippo pathway organization and oncogenic alteration in evolution. Sci Rep. 2020;10:3173 pubmed publisher |
Ortega J, Daley E, Kour S, Samani M, Tellez L, Smith H, et al. Nucleocytoplasmic Proteomic Analysis Uncovers eRF1 and Nonsense-Mediated Decay as Modifiers of ALS/FTD C9orf72 Toxicity. Neuron. 2020;106:90-107.e13 pubmed publisher |
Berg M, Naams J, Hautala L, Tolvanen T, Ahonen J, Lehtonen S, et al. Novel Sulfonanilide Inhibitors of SHIP2 Enhance Glucose Uptake into Cultured Myotubes. ACS Omega. 2020;5:1430-1438 pubmed publisher |
Yan K, Rousseau J, Machol K, Cross L, Agre K, Gibson C, et al. Deficient histone H3 propionylation by BRPF1-KAT6 complexes in neurodevelopmental disorders and cancer. Sci Adv. 2020;6:eaax0021 pubmed publisher |
Chronopoulos A, Thorpe S, Cortés E, Lachowski D, Rice A, Mykuliak V, et al. Syndecan-4 tunes cell mechanics by activating the kindlin-integrin-RhoA pathway. Nat Mater. 2020;19:669-678 pubmed publisher |
Lovejoy C, Takai K, Huh M, Picketts D, de Lange T. ATRX affects the repair of telomeric DSBs by promoting cohesion and a DAXX-dependent activity. PLoS Biol. 2020;18:e3000594 pubmed publisher |
Yorimitsu T, Sato K. Sec16 function in ER export and autophagy is independent of its phosphorylation in Saccharomyces cerevisiae. Mol Biol Cell. 2020;31:149-156 pubmed publisher |
Li Z, Huan C, Wang H, Liu Y, Liu X, Su X, et al. TRIM21-mediated proteasomal degradation of SAMHD1 regulates its antiviral activity. EMBO Rep. 2020;21:e47528 pubmed publisher |
Spadotto V, Giambruno R, Massignani E, Mihailovich M, Maniaci M, Patuzzo F, et al. PRMT1-mediated methylation of the microprocessor-associated proteins regulates microRNA biogenesis. Nucleic Acids Res. 2020;48:96-115 pubmed publisher |
Gavini C, Cook T, Rademacher D, Mansuy Aubert V. Hypothalamic C2-domain protein involved in MC4R trafficking and control of energy balance. Metabolism. 2020;102:153990 pubmed publisher |
Zheng B, Zhang J, Zheng T, Wang H, Li Z, Huan C, et al. ATP1B3 cooperates with BST-2 to promote hepatitis B virus restriction. J Med Virol. 2020;92:201-209 pubmed publisher |
Hajicek N, Keith N, Siraliev Perez E, Temple B, Huang W, Zhang Q, et al. Structural basis for the activation of PLC-γ isozymes by phosphorylation and cancer-associated mutations. elife. 2019;8: pubmed publisher |
Lee A, Zhu Y, Sabo Y, Goff S. Embryonic Cells Redistribute SUMO1 upon Forced SUMO1 Overexpression. MBio. 2019;10: pubmed publisher |
Ficarelli M, Antzin Anduetza I, Hugh White R, Firth A, Sertkaya H, Wilson H, et al. CpG dinucleotides inhibit HIV-1 replication through zinc finger antiviral protein (ZAP)-dependent and -independent mechanisms. J Virol. 2019;: pubmed publisher |
Wisesa S, Yamamoto Y, Sakisaka T. TMCC3 localizes at the three-way junctions for the proper tubular network of the endoplasmic reticulum. Biochem J. 2019;476:3241-3260 pubmed publisher |
Liu S, Wang S, Zou L, Li J, Song C, Chen J, et al. TMC1 is an essential component of a leak channel that modulates tonotopy and excitability of auditory hair cells in mice. elife. 2019;8: pubmed publisher |
Meng X, McGraw C, Wang W, Jing J, Yeh S, Wang L, et al. Neurexophilin4 is a selectively expressed α-neurexin ligand that modulates specific cerebellar synapses and motor functions. elife. 2019;8: pubmed publisher |
Subramanian J, Michel K, Benoit M, Nedivi E. CPG15/Neuritin Mimics Experience in Selecting Excitatory Synapses for Stabilization by Facilitating PSD95 Recruitment. Cell Rep. 2019;28:1584-1595.e5 pubmed publisher |
Carvalho J, Fortunato I, Fonseca C, Pezzarossa A, Barbacena P, Domínguez Cejudo M, et al. Non-canonical Wnt signaling regulates junctional mechanocoupling during angiogenic collective cell migration. elife. 2019;8: pubmed publisher |
Carreras Sureda A, Jaña F, Urra H, Durand S, Mortenson D, Sagredo A, et al. Non-canonical function of IRE1α determines mitochondria-associated endoplasmic reticulum composition to control calcium transfer and bioenergetics. Nat Cell Biol. 2019;: pubmed publisher |
Lee Y, Chen M, Lee J, Zhang J, Lin S, Fu T, et al. Reactivation of PTEN tumor suppressor for cancer treatment through inhibition of a MYC-WWP1 inhibitory pathway. Science. 2019;364: pubmed publisher |
Carty M, Kearney J, Shanahan K, Hams E, Sugisawa R, Connolly D, et al. Cell Survival and Cytokine Release after Inflammasome Activation Is Regulated by the Toll-IL-1R Protein SARM. Immunity. 2019;50:1412-1424.e6 pubmed publisher |
Sanders S, De Simone F, Thomas G. mTORC1 Signaling Is Palmitoylation-Dependent in Hippocampal Neurons and Non-neuronal Cells and Involves Dynamic Palmitoylation of LAMTOR1 and mTOR. Front Cell Neurosci. 2019;13:115 pubmed publisher |
Liang N, Damdimopoulos A, Goñi S, Huang Z, Vedin L, Jakobsson T, et al. Hepatocyte-specific loss of GPS2 in mice reduces non-alcoholic steatohepatitis via activation of PPARα. Nat Commun. 2019;10:1684 pubmed publisher |
Jung J, Macalino S, Cui M, Kim J, Kim H, Song D, et al. Transmembrane 4 L Six Family Member 5 Senses Arginine for mTORC1 Signaling. Cell Metab. 2019;29:1306-1319.e7 pubmed publisher |
Cruz Ortega J, Boucard A. Actin cytoskeleton remodeling defines a distinct cellular function for adhesion G protein-coupled receptors ADGRL/latrophilins 1, 2 and 3. Biol Open. 2019;8: pubmed publisher |
Tai Y, Gallo N, Wang M, Yu J, Van Aelst L. Axo-axonic Innervation of Neocortical Pyramidal Neurons by GABAergic Chandelier Cells Requires AnkyrinG-Associated L1CAM. Neuron. 2019;102:358-372.e9 pubmed publisher |
Burkhart B, Febvre H, Santangelo T. Distinct Physiological Roles of the Three Ferredoxins Encoded in the Hyperthermophilic Archaeon Thermococcus kodakarensis. MBio. 2019;10: pubmed publisher |
Lashhab R, Rumley A, Arutyunov D, Rizvi M, You C, Dimke H, et al. The kidney anion exchanger 1 affects tight junction properties via claudin-4. Sci Rep. 2019;9:3099 pubmed publisher |
Nakamura K, Saredi G, Becker J, Foster B, Nguyen N, Beyer T, et al. H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids. Nat Cell Biol. 2019;21:311-318 pubmed publisher |
Kusakabe S, Suzuki T, Sugiyama Y, Haga S, Horike K, Tokunaga M, et al. USP15 Participates in Hepatitis C Virus Propagation through Regulation of Viral RNA Translation and Lipid Droplet Formation. J Virol. 2019;93: pubmed publisher |
Sun J, Carlson Stevermer J, Das U, Shen M, Delenclos M, Snead A, et al. CRISPR/Cas9 editing of APP C-terminus attenuates β-cleavage and promotes α-cleavage. Nat Commun. 2019;10:53 pubmed publisher |
Cui Y, Carosi J, Yang Z, Ariotti N, Kerr M, Parton R, et al. Retromer has a selective function in cargo sorting via endosome transport carriers. J Cell Biol. 2019;218:615-631 pubmed publisher |
Miyazawa M, Bogdan A, Tsuji Y. Perturbation of Iron Metabolism by Cisplatin through Inhibition of Iron Regulatory Protein 2. Cell Chem Biol. 2019;26:85-97.e4 pubmed publisher |
Chen X, Chanda A, Ikeuchi Y, Zhang X, Goodman J, Reddy N, et al. The Transcriptional Regulator SnoN Promotes the Proliferation of Cerebellar Granule Neuron Precursors in the Postnatal Mouse Brain. J Neurosci. 2019;39:44-62 pubmed publisher |
Yu T, Kimble M, Symington L. Sae2 antagonizes Rad9 accumulation at DNA double-strand breaks to attenuate checkpoint signaling and facilitate end resection. Proc Natl Acad Sci U S A. 2018;115:E11961-E11969 pubmed publisher |
Cargnin F, Kwon J, Katzman S, Chen B, Lee J, Lee S. FOXG1 Orchestrates Neocortical Organization and Cortico-Cortical Connections. Neuron. 2018;100:1083-1096.e5 pubmed publisher |
Nguyen H, Labella S, Silva N, Jantsch V, Zetka M. C. elegans ZHP-4 is required at multiple distinct steps in the formation of crossovers and their transition to segregation competent chiasmata. PLoS Genet. 2018;14:e1007776 pubmed publisher |
Kikuchi S, Asakura Y, Imai M, Nakahira Y, Kotani Y, Hashiguchi Y, et al. A Ycf2-FtsHi Heteromeric AAA-ATPase Complex Is Required for Chloroplast Protein Import. Plant Cell. 2018;30:2677-2703 pubmed publisher |
Gavini C, Bookout A, Bonomo R, Gautron L, Lee S, Mansuy Aubert V. Liver X Receptors Protect Dorsal Root Ganglia from Obesity-Induced Endoplasmic Reticulum Stress and Mechanical Allodynia. Cell Rep. 2018;25:271-277.e4 pubmed publisher |
Chuhma N, Mingote S, Yetnikoff L, Kalmbach A, Ma T, Ztaou S, et al. Dopamine neuron glutamate cotransmission evokes a delayed excitation in lateral dorsal striatal cholinergic interneurons. elife. 2018;7: pubmed publisher |
Condomitti G, Wierda K, Schroeder A, Rubio S, Vennekens K, Orlandi C, et al. An Input-Specific Orphan Receptor GPR158-HSPG Interaction Organizes Hippocampal Mossy Fiber-CA3 Synapses. Neuron. 2018;100:201-215.e9 pubmed publisher |
Lauwers E, Wang Y, Gallardo R, van der Kant R, Michiels E, Swerts J, et al. Hsp90 Mediates Membrane Deformation and Exosome Release. Mol Cell. 2018;71:689-702.e9 pubmed publisher |
Sharma S, Lewinski M, Guatelli J. An N-Glycosylated Form of SERINC5 Is Specifically Incorporated into HIV-1 Virions. J Virol. 2018;92: pubmed publisher |
Singh R, Stoneham C, Lim C, Jia X, Guenaga J, Wyatt R, et al. Phosphoserine acidic cluster motifs bind distinct basic regions on the μ subunits of clathrin adaptor protein complexes. J Biol Chem. 2018;293:15678-15690 pubmed publisher |
Tu Y, Duman J, Tolias K. The Adhesion-GPCR BAI1 Promotes Excitatory Synaptogenesis by Coordinating Bidirectional Trans-synaptic Signaling. J Neurosci. 2018;38:8388-8406 pubmed publisher |
Brockhaus J, Schreitmüller M, Repetto D, Klatt O, Reissner C, ELMSLIE K, et al. ?-Neurexins Together with ?2?-1 Auxiliary Subunits Regulate Ca2+ Influx through Cav2.1 Channels. J Neurosci. 2018;38:8277-8294 pubmed publisher |
Ghezraoui H, Oliveira C, Becker J, Bilham K, Moralli D, Anzilotti C, et al. 53BP1 cooperation with the REV7-shieldin complex underpins DNA structure-specific NHEJ. Nature. 2018;560:122-127 pubmed publisher |
Asada S, Goyama S, Inoue D, Shikata S, Takeda R, Fukushima T, et al. Mutant ASXL1 cooperates with BAP1 to promote myeloid leukaemogenesis. Nat Commun. 2018;9:2733 pubmed publisher |
Ciftci Yilmaz S, Au W, Mishra P, Eisenstatt J, Chang J, Dawson A, et al. A Genome-Wide Screen Reveals a Role for the HIR Histone Chaperone Complex in Preventing Mislocalization of Budding Yeast CENP-A. Genetics. 2018;210:203-218 pubmed publisher |
Huang Z, Barker D, Gibbins J, Dash P. Talin is a substrate for SUMOylation in migrating cancer cells. Exp Cell Res. 2018;370:417-425 pubmed publisher |
English E, Mahn S, Marchese A. Endocytosis is required for CXC chemokine receptor type 4 (CXCR4)-mediated Akt activation and antiapoptotic signaling. J Biol Chem. 2018;293:11470-11480 pubmed publisher |
Noto T, Mochizuki K. Small RNA-Mediated trans-Nuclear and trans-Element Communications in Tetrahymena DNA Elimination. Curr Biol. 2018;28:1938-1949.e5 pubmed publisher |
Hopp S, Bihlmeyer N, Corradi J, Vanderburg C, Cacace A, Das S, et al. Neuronal calcineurin transcriptional targets parallel changes observed in Alzheimer disease brain. J Neurochem. 2018;147:24-39 pubmed publisher |
Antonucci J, Kim S, St Gelais C, Bonifati S, Li T, Buzovetsky O, et al. SAMHD1 Impairs HIV-1 Gene Expression and Negatively Modulates Reactivation of Viral Latency in CD4+ T Cells. J Virol. 2018;92: pubmed publisher |
Rong Y, Bansal P, Wei P, Guo H, Correia K, Parris J, et al. Glycosylation of Cblns attenuates their receptor binding. Brain Res. 2018;1694:129-139 pubmed publisher |
Sondo E, Falchi F, Caci E, Ferrera L, Giacomini E, Pesce E, et al. Pharmacological Inhibition of the Ubiquitin Ligase RNF5 Rescues F508del-CFTR in Cystic Fibrosis Airway Epithelia. Cell Chem Biol. 2018;25:891-905.e8 pubmed publisher |
Carpenter K, Bell R, Yunus J, Amon A, Berchowitz L. Phosphorylation-Mediated Clearance of Amyloid-like Assemblies in Meiosis. Dev Cell. 2018;45:392-405.e6 pubmed publisher |
Martin J, Mendonça L, Marusinec R, Zuczek J, Angert I, Blower R, et al. Critical Role of the Human T-Cell Leukemia Virus Type 1 Capsid N-Terminal Domain for Gag-Gag Interactions and Virus Particle Assembly. J Virol. 2018;92: pubmed publisher |
Tan K, Haelterman N, Kwartler C, Regalado E, Lee P, Nagarkar Jaiswal S, et al. Ari-1 Regulates Myonuclear Organization Together with Parkin and Is Associated with Aortic Aneurysms. Dev Cell. 2018;45:226-244.e8 pubmed publisher |
Sakr M, Li X, Sabeh F, Feinberg T, Tesmer J, Tang Y, et al. Tracking the Cartoon mouse phenotype: Hemopexin domain-dependent regulation of MT1-MMP pericellular collagenolytic activity. J Biol Chem. 2018;293:8113-8127 pubmed publisher |
Stankova T, Piepkorn L, Bayer T, Jahn O, Tirard M. SUMO1-conjugation is altered during normal aging but not by increased amyloid burden. Aging Cell. 2018;17:e12760 pubmed publisher |
Mygind K, Störiko T, Freiberg M, Samsøe Petersen J, Schwarz J, Andersen O, et al. Sorting nexin 9 (SNX9) regulates levels of the transmembrane ADAM9 at the cell surface. J Biol Chem. 2018;293:8077-8088 pubmed publisher |
Scheele S, Geiger J, Derocher A, Choi R, Smith T, Hulverson M, et al. Toxoplasma Calcium-Dependent Protein Kinase 1 Inhibitors: Probing Activity and Resistance Using Cellular Thermal Shift Assays. Antimicrob Agents Chemother. 2018;62: pubmed publisher |
Kuriyama S, Tsuji T, Sakuma T, Yamamoto T, Tanaka M. PLEKHN1 promotes apoptosis by enhancing Bax-Bak hetro-oligomerization through interaction with Bid in human colon cancer. Cell Death Discov. 2018;4:11 pubmed publisher |
Yu K, Davidson C, Wójtowicz A, Lisboa L, Wang T, Airo A, et al. LILRB1 polymorphisms influence posttransplant HCMV susceptibility and ligand interactions. J Clin Invest. 2018;128:1523-1537 pubmed publisher |
Qiu T, Crane J, Xie L, Xian L, Xie H, Cao X. IGF-I induced phosphorylation of PTH receptor enhances osteoblast to osteocyte transition. Bone Res. 2018;6:5 pubmed publisher |
Okiyoneda T, Veit G, Sakai R, Aki M, Fujihara T, Higashi M, et al. Chaperone-Independent Peripheral Quality Control of CFTR by RFFL E3 Ligase. Dev Cell. 2018;44:694-708.e7 pubmed publisher |
Riva L, Song O, Prentoe J, Helle F, L homme L, Gattolliat C, et al. Identification of Piperazinylbenzenesulfonamides as New Inhibitors of Claudin-1 Trafficking and Hepatitis C Virus Entry. J Virol. 2018;92: pubmed publisher |
Gennarino V, Palmer E, McDonell L, Wang L, Adamski C, Koire A, et al. A Mild PUM1 Mutation Is Associated with Adult-Onset Ataxia, whereas Haploinsufficiency Causes Developmental Delay and Seizures. Cell. 2018;172:924-936.e11 pubmed publisher |
Feld C, Sahu P, Frech M, Finkernagel F, Nist A, Stiewe T, et al. Combined cistrome and transcriptome analysis of SKI in AML cells identifies SKI as a co-repressor for RUNX1. Nucleic Acids Res. 2018;46:3412-3428 pubmed publisher |
Meyer C, Garzia A, Mazzola M, Gerstberger S, Molina H, Tuschl T. The TIA1 RNA-Binding Protein Family Regulates EIF2AK2-Mediated Stress Response and Cell Cycle Progression. Mol Cell. 2018;69:622-635.e6 pubmed publisher |
Collopy L, Ware T, Goncalves T, Í Kongsstovu S, Yang Q, Amelina H, et al. LARP7 family proteins have conserved function in telomerase assembly. Nat Commun. 2018;9:557 pubmed publisher |
Serrano Perez M, Tilley F, Nevo F, Arrondel C, Sbissa S, Martin G, et al. Endoplasmic reticulum-retained podocin mutants are massively degraded by the proteasome. J Biol Chem. 2018;293:4122-4133 pubmed publisher |
Jiang L, Jiang W, Tian N, Xiong Y, Liu J, Wei J, et al. Ring finger protein 145 (RNF145) is a ubiquitin ligase for sterol-induced degradation of HMG-CoA reductase. J Biol Chem. 2018;293:4047-4055 pubmed publisher |
Canton J, Fehr A, Fernandez Delgado R, Gutierrez Alvarez F, Sanchez Aparicio M, Garcia Sastre A, et al. MERS-CoV 4b protein interferes with the NF-?B-dependent innate immune response during infection. PLoS Pathog. 2018;14:e1006838 pubmed publisher |
Döring T, Zeyen L, Bartusch C, Prange R. Hepatitis B Virus Subverts the Autophagy Elongation Complex Atg5-12/16L1 and Does Not Require Atg8/LC3 Lipidation for Viral Maturation. J Virol. 2018;92: pubmed publisher |
Li Q, Hua Y, Yang Y, He X, Zhu W, Wang J, et al. T Cell Factor 7 (TCF7)/TCF1 Feedback Controls Osteocalcin Signaling in Brown Adipocytes Independent of the Wnt/β-Catenin Pathway. Mol Cell Biol. 2018;38: pubmed publisher |
Karvonen H, Summala K, Niininen W, Barker H, Ungureanu D. Interaction between ROR1 and MuSK activation complex in myogenic cells. FEBS Lett. 2018;592:434-445 pubmed publisher |
Dreisig K, Kristensen N, Dommer M, Jørgensen N, Kornum B. N-terminal tagging of human P2X7 receptor disturbs calcium influx and dye uptake. Purinergic Signal. 2018;14:83-90 pubmed publisher |
Lee M, Rusin S, Jenkins N, Kettenbach A, Moseley J. Mechanisms Connecting the Conserved Protein Kinases Ssp1, Kin1, and Pom1 in Fission Yeast Cell Polarity and Division. Curr Biol. 2018;28:84-92.e4 pubmed publisher |
Ordonez D, Lee M, Feany M. α-synuclein Induces Mitochondrial Dysfunction through Spectrin and the Actin Cytoskeleton. Neuron. 2018;97:108-124.e6 pubmed publisher |
Wang Q, Chiu S, Koropouli E, Hong I, Mitchell S, Easwaran T, et al. Neuropilin-2/PlexinA3 Receptors Associate with GluA1 and Mediate Sema3F-Dependent Homeostatic Scaling in Cortical Neurons. Neuron. 2017;96:1084-1098.e7 pubmed publisher |
Mizoguchi T, Ikeda S, Watanabe S, Sugawara M, Itoh M. Mib1 contributes to persistent directional cell migration by regulating the Ctnnd1-Rac1 pathway. Proc Natl Acad Sci U S A. 2017;114:E9280-E9289 pubmed publisher |
Nishiyama J, Mikuni T, Yasuda R. Virus-Mediated Genome Editing via Homology-Directed Repair in Mitotic and Postmitotic Cells in Mammalian Brain. Neuron. 2017;96:755-768.e5 pubmed publisher |
Verma M, Callio J, Otero P, Sekler I, Wills Z, Chu C. Mitochondrial Calcium Dysregulation Contributes to Dendrite Degeneration Mediated by PD/LBD-Associated LRRK2 Mutants. J Neurosci. 2017;37:11151-11165 pubmed publisher |
Opalko H, Moseley J. Dynamic regulation of Cdr1 kinase localization and phosphorylation during osmotic stress. J Biol Chem. 2017;292:18457-18468 pubmed publisher |
Zhang S, Xu C, Larrimore K, Ng D. Slp1-Emp65: A Guardian Factor that Protects Folding Polypeptides from Promiscuous Degradation. Cell. 2017;171:346-357.e12 pubmed publisher |
Zhang Z, Jones A, Wu W, Kim J, Kang Y, Bi X, et al. Role of remodeling and spacing factor 1 in histone H2A ubiquitination-mediated gene silencing. Proc Natl Acad Sci U S A. 2017;114:E7949-E7958 pubmed publisher |
Lessel D, Wu D, Trujillo C, Ramezani T, Lessel I, Alwasiyah M, et al. Dysfunction of the MDM2/p53 axis is linked to premature aging. J Clin Invest. 2017;127:3598-3608 pubmed publisher |
Smith C, Kharkwal H, Wilson D. Expression and Subcellular Localization of the Kaposi's Sarcoma-Associated Herpesvirus K15P Protein during Latency and Lytic Reactivation in Primary Effusion Lymphoma Cells. J Virol. 2017;91: pubmed publisher |
Shibutani S, Okazaki H, Iwata H. Dynamin-dependent amino acid endocytosis activates mechanistic target of rapamycin complex 1 (mTORC1). J Biol Chem. 2017;292:18052-18061 pubmed publisher |
Yoshida Y, Yasuda S, Fujita T, Hamasaki M, Murakami A, Kawawaki J, et al. Ubiquitination of exposed glycoproteins by SCFFBXO27 directs damaged lysosomes for autophagy. Proc Natl Acad Sci U S A. 2017;114:8574-8579 pubmed publisher |
Pae J, Cinalli R, Marzio A, Pagano M, Lehmann R. GCL and CUL3 Control the Switch between Cell Lineages by Mediating Localized Degradation of an RTK. Dev Cell. 2017;42:130-142.e7 pubmed publisher |
Takahashi M, Li Y, Dillon T, Kariya Y, Stork P. Phosphorylation of the C-Raf N Region Promotes Raf Dimerization. Mol Cell Biol. 2017;37: pubmed publisher |
Li M, Tan I, Ma S, Hockings C, Kratina T, Dengler M, et al. BAK ?6 permits activation by BH3-only proteins and homooligomerization via the canonical hydrophobic groove. Proc Natl Acad Sci U S A. 2017;114:7629-7634 pubmed publisher |
Trautz B, Wiedemann H, Lüchtenborg C, Pierini V, Kranich J, Glass B, et al. The host-cell restriction factor SERINC5 restricts HIV-1 infectivity without altering the lipid composition and organization of viral particles. J Biol Chem. 2017;292:13702-13713 pubmed publisher |
Schommartz T, Tang J, Brost R, Brune W. Differential Requirement of Human Cytomegalovirus UL112-113 Protein Isoforms for Viral Replication. J Virol. 2017;91: pubmed publisher |
Tseng P, Henderson P, Hergarden A, Patriarchi T, Coleman A, Lillya M, et al. ?-Actinin Promotes Surface Localization and Current Density of the Ca2+ Channel CaV1.2 by Binding to the IQ Region of the ?1 Subunit. Biochemistry. 2017;56:3669-3681 pubmed publisher |
Daniel J, Cooper B, Palvimo J, Zhang F, Brose N, Tirard M. Analysis of SUMO1-conjugation at synapses. elife. 2017;6: pubmed publisher |
Yonezawa T, Takahashi H, Shikata S, Liu X, Tamura M, Asada S, et al. The ubiquitin ligase STUB1 regulates stability and activity of RUNX1 and RUNX1-RUNX1T1. J Biol Chem. 2017;292:12528-12541 pubmed publisher |
Finlay D, Cawston E, Grimsey N, Hunter M, Korde A, Vemuri V, et al. G?s signalling of the CB1 receptor and the influence of receptor number. Br J Pharmacol. 2017;174:2545-2562 pubmed publisher |
Leitherer S, Clos J, Liebler Tenorio E, Schleicher U, Bogdan C, Soulat D. Characterization of the Protein Tyrosine Phosphatase LmPRL-1 Secreted by Leishmania major via the Exosome Pathway. Infect Immun. 2017;85: pubmed publisher |
Zhu W, He X, Hua Y, Li Q, Wang J, Gan X. The E3 ubiquitin ligase WWP2 facilitates RUNX2 protein transactivation in a mono-ubiquitination manner during osteogenic differentiation. J Biol Chem. 2017;292:11178-11188 pubmed publisher |
Alekseyenko A, Walsh E, Zee B, Pakozdi T, Hsi P, Lemieux M, et al. Ectopic protein interactions within BRD4-chromatin complexes drive oncogenic megadomain formation in NUT midline carcinoma. Proc Natl Acad Sci U S A. 2017;114:E4184-E4192 pubmed publisher |
Kim J, Kim T, Lee H, Nikapitiya C, Uddin M, Park M, et al. Rubicon Modulates Antiviral Type I Interferon (IFN) Signaling by Targeting IFN Regulatory Factor 3 Dimerization. J Virol. 2017;91: pubmed publisher |
Yadav L, Tamene F, Göös H, van Drogen A, Katainen R, Aebersold R, et al. Systematic Analysis of Human Protein Phosphatase Interactions and Dynamics. Cell Syst. 2017;4:430-444.e5 pubmed publisher |
Opazo T, Garcés A, Tapia D, Barraza F, Bravo A, Schwenke T, et al. Functional Evidence of the Involvement of the Dynein Light Chain DYNLRB2 in Murine Leukemia Virus Infection. J Virol. 2017;91: pubmed publisher |
Ebata T, Mitsui Y, Sugimoto W, Maeda M, Araki K, Machiyama H, et al. Substrate Stiffness Influences Doxorubicin-Induced p53 Activation via ROCK2 Expression. Biomed Res Int. 2017;2017:5158961 pubmed publisher |
Athmer J, Fehr A, Grunewald M, Smith E, Denison M, Perlman S. In Situ Tagged nsp15 Reveals Interactions with Coronavirus Replication/Transcription Complex-Associated Proteins. MBio. 2017;8: pubmed publisher |
Gong Y, Handa N, Kowalczykowski S, de Lange T. PHF11 promotes DSB resection, ATR signaling, and HR. Genes Dev. 2017;31:46-58 pubmed publisher |
Jiang C, Kawabe H, Rotin D. The Ubiquitin Ligase Nedd4L Regulates the Na/K/2Cl Co-transporter NKCC1/SLC12A2 in the Colon. J Biol Chem. 2017;292:3137-3145 pubmed publisher |
Maeda R, Tamashiro H, Takano K, Takahashi H, Suzuki H, Saito S, et al. TBP-like Protein (TLP) Disrupts the p53-MDM2 Interaction and Induces Long-lasting p53 Activation. J Biol Chem. 2017;292:3201-3212 pubmed publisher |
Liszczak G, Brown Z, Kim S, Oslund R, David Y, Muir T. Genomic targeting of epigenetic probes using a chemically tailored Cas9 system. Proc Natl Acad Sci U S A. 2017;114:681-686 pubmed publisher |
Taetzsch T, Tenga M, Valdez G. Muscle Fibers Secrete FGFBP1 to Slow Degeneration of Neuromuscular Synapses during Aging and Progression of ALS. J Neurosci. 2017;37:70-82 pubmed publisher |
Tam K, Schultz M, Reyes Robles T, Vanwalscappel B, Horton J, Alonzo F, et al. Staphylococcus aureus Leukocidin LukED and HIV-1 gp120 Target Different Sequence Determinants on CCR5. MBio. 2016;7: pubmed publisher |
Hanke L, Knockenhauer K, Brewer R, van Diest E, Schmidt F, Schwartz T, et al. The Antiviral Mechanism of an Influenza A Virus Nucleoprotein-Specific Single-Domain Antibody Fragment. MBio. 2016;7: pubmed publisher |
Cai H, Liu A. Spop promotes skeletal development and homeostasis by positively regulating Ihh signaling. Proc Natl Acad Sci U S A. 2016;113:14751-14756 pubmed publisher |
Kataoka K, Mochizuki K. Heterochromatin aggregation during DNA elimination in Tetrahymena is facilitated by a prion-like protein. J Cell Sci. 2017;130:480-489 pubmed publisher |
Yagita Y, Shinohara K, Abe Y, Nakagawa K, Al Owain M, Alkuraya F, et al. Deficiency of a Retinal Dystrophy Protein, Acyl-CoA Binding Domain-containing 5 (ACBD5), Impairs Peroxisomal ?-Oxidation of Very-long-chain Fatty Acids. J Biol Chem. 2017;292:691-705 pubmed publisher |
Haggie P, Phuan P, Tan J, Xu H, Avramescu R, Perdomo D, et al. Correctors and Potentiators Rescue Function of the Truncated W1282X-Cystic Fibrosis Transmembrane Regulator (CFTR) Translation Product. J Biol Chem. 2017;292:771-785 pubmed publisher |
Gao L, Chen J, Gao J, Wang H, Xiong W. Super-resolution microscopy reveals the insulin-resistance-regulated reorganization of GLUT4 on plasma membranes. J Cell Sci. 2017;130:396-405 pubmed publisher |
Zhang H, Sun S, Wu L, Pchitskaya E, Zakharova O, Fon Tacer K, et al. Store-Operated Calcium Channel Complex in Postsynaptic Spines: A New Therapeutic Target for Alzheimer's Disease Treatment. J Neurosci. 2016;36:11837-11850 pubmed |
Baehr C, Huntoon C, Hoang S, Jerde C, Karnitz L. Glycogen Synthase Kinase 3 (GSK-3)-mediated Phosphorylation of Uracil N-Glycosylase 2 (UNG2) Facilitates the Repair of Floxuridine-induced DNA Lesions and Promotes Cell Survival. J Biol Chem. 2016;291:26875-26885 pubmed publisher |
Kaufmann T, Kukolj E, Brachner A, Beltzung E, Bruno M, Kostrhon S, et al. SIRT2 regulates nuclear envelope reassembly through ANKLE2 deacetylation. J Cell Sci. 2016;129:4607-4621 pubmed |
Matsuo Y, Maurer S, Yukawa M, Zakian S, Singleton M, Surrey T, et al. An unconventional interaction between Dis1/TOG and Mal3/EB1 in fission yeast promotes the fidelity of chromosome segregation. J Cell Sci. 2016;129:4592-4606 pubmed |
Kilroy G, Burk D, Floyd Z. Siah2 Protein Mediates Early Events in Commitment to an Adipogenic Pathway. J Biol Chem. 2016;291:27289-27297 pubmed publisher |
Stoeber M, Schellenberger P, Siebert C, Leyrat C, Helenius A, Grünewald K. Model for the architecture of caveolae based on a flexible, net-like assembly of Cavin1 and Caveolin discs. Proc Natl Acad Sci U S A. 2016;113:E8069-E8078 pubmed |
Kaczmarska Z, Ortega E, Goudarzi A, Huang H, Kim S, Márquez J, et al. Structure of p300 in complex with acyl-CoA variants. Nat Chem Biol. 2017;13:21-29 pubmed publisher |
Despras E, Sittewelle M, Pouvelle C, Delrieu N, Cordonnier A, Kannouche P. Rad18-dependent SUMOylation of human specialized DNA polymerase eta is required to prevent under-replicated DNA. Nat Commun. 2016;7:13326 pubmed publisher |
Zhang M, Zhang M, Zhang Q, Zhu G, Yuan L, Zhang D, et al. USP18 recruits USP20 to promote innate antiviral response through deubiquitinating STING/MITA. Cell Res. 2016;26:1302-1319 pubmed publisher |
Guirouilh Barbat J, Gelot C, Xie A, Dardillac E, Scully R, Lopez B. 53BP1 Protects against CtIP-Dependent Capture of Ectopic Chromosomal Sequences at the Junction of Distant Double-Strand Breaks. PLoS Genet. 2016;12:e1006230 pubmed publisher |
Lin Z, Li S, Feng C, Yang S, Wang H, Ma D, et al. Stabilizing mutations of KLHL24 ubiquitin ligase cause loss of keratin 14 and human skin fragility. Nat Genet. 2016;48:1508-1516 pubmed publisher |
Piwko W, Mlejnkova L, Mutreja K, Ranjha L, Stafa D, Smirnov A, et al. The MMS22L-TONSL heterodimer directly promotes RAD51-dependent recombination upon replication stress. EMBO J. 2016;35:2584-2601 pubmed |
Gómez H L, Felipe Medina N, Sanchez Martin M, Davies O, Ramos I, García Tuñón I, et al. C14ORF39/SIX6OS1 is a constituent of the synaptonemal complex and is essential for mouse fertility. Nat Commun. 2016;7:13298 pubmed publisher |
Boehm E, Zornoza M, Jourdain A, Delmiro Magdalena A, Garcia Consuegra I, Torres Merino R, et al. Role of FAST Kinase Domains 3 (FASTKD3) in Post-transcriptional Regulation of Mitochondrial Gene Expression. J Biol Chem. 2016;291:25877-25887 pubmed |
Rademacher N, Schmerl B, Lardong J, Wahl M, Shoichet S. MPP2 is a postsynaptic MAGUK scaffold protein that links SynCAM1 cell adhesion molecules to core components of the postsynaptic density. Sci Rep. 2016;6:35283 pubmed publisher |
Ramachandran S, Osterhaus S, Parekh K, Jacobi A, Behlke M, McCray P. SYVN1, NEDD8, and FBXO2 Proteins Regulate ?F508 Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Ubiquitin-mediated Proteasomal Degradation. J Biol Chem. 2016;291:25489-25504 pubmed |
Zee B, Dibona A, Alekseyenko A, French C, Kuroda M. The Oncoprotein BRD4-NUT Generates Aberrant Histone Modification Patterns. PLoS ONE. 2016;11:e0163820 pubmed publisher |
Yadav S, Magre I, Singh A, Khuperkar D, Joseph J. Regulation of aPKC activity by Nup358 dependent SUMO modification. Sci Rep. 2016;6:34100 pubmed publisher |
Pashkova N, Peterson T, Krishnamani V, Breheny P, Stamnes M, Piper R. DEEPN as an Approach for Batch Processing of Yeast 2-Hybrid Interactions. Cell Rep. 2016;17:303-315 pubmed publisher |
Gu Q, Zhang Z, Cano Ortiz L, Franco A, Haussinger D, Munk C. Feline Immunodeficiency Virus Vif N-Terminal Residues Selectively Counteract Feline APOBEC3s. J Virol. 2016;90:10545-10557 pubmed publisher |
Hashimoto A, Hashimoto S, Sugino H, Yoshikawa A, Onodera Y, Handa H, et al. ZEB1 induces EPB41L5 in the cancer mesenchymal program that drives ARF6-based invasion, metastasis and drug resistance. Oncogenesis. 2016;5:e259 pubmed publisher |
Hwang J, Lee J, Pallas D. Leucine Carboxyl Methyltransferase 1 (LCMT-1) Methylates Protein Phosphatase 4 (PP4) and Protein Phosphatase 6 (PP6) and Differentially Regulates the Stable Formation of Different PP4 Holoenzymes. J Biol Chem. 2016;291:21008-21019 pubmed |
Damez Werno D, Sun H, Scobie K, Shao N, Rabkin J, Dias C, et al. Histone arginine methylation in cocaine action in the nucleus accumbens. Proc Natl Acad Sci U S A. 2016;113:9623-8 pubmed publisher |
Sanchez M, Tran K, Valli J, Hobbs S, Johnson E, Gluenz E, et al. KHARON Is an Essential Cytoskeletal Protein Involved in the Trafficking of Flagellar Membrane Proteins and Cell Division in African Trypanosomes. J Biol Chem. 2016;291:19760-73 pubmed publisher |
Faden F, Ramezani T, Mielke S, Almudi I, Nairz K, Froehlich M, et al. Phenotypes on demand via switchable target protein degradation in multicellular organisms. Nat Commun. 2016;7:12202 pubmed publisher |
Jiménez Canino R, Fernandes M, Alvarez de la Rosa D. Phosphorylation of Mineralocorticoid Receptor Ligand Binding Domain Impairs Receptor Activation and Has a Dominant Negative Effect over Non-phosphorylated Receptors. J Biol Chem. 2016;291:19068-78 pubmed publisher |
Barquilla A, Lamberto I, Noberini R, Heynen Genel S, Brill L, Pasquale E. Protein kinase A can block EphA2 receptor-mediated cell repulsion by increasing EphA2 S897 phosphorylation. Mol Biol Cell. 2016;27:2757-70 pubmed publisher |
Avgousti D, Herrmann C, Kulej K, Pancholi N, Sekulic N, Petrescu J, et al. A core viral protein binds host nucleosomes to sequester immune danger signals. Nature. 2016;535:173-7 pubmed |
Szargel R, Shani V, Abd Elghani F, Mekies L, Liani E, Rott R, et al. The PINK1, synphilin-1 and SIAH-1 complex constitutes a novel mitophagy pathway. Hum Mol Genet. 2016;25:3476-3490 pubmed publisher |
Miura Y, Hongu T, Yamauchi Y, Funakoshi Y, Katagiri N, Ohbayashi N, et al. ACAP3 regulates neurite outgrowth through its GAP activity specific to Arf6 in mouse hippocampal neurons. Biochem J. 2016;473:2591-602 pubmed publisher |
Dick M, Sborgi L, Rühl S, Hiller S, Broz P. ASC filament formation serves as a signal amplification mechanism for inflammasomes. Nat Commun. 2016;7:11929 pubmed publisher |
Su P, Chen S, Zheng Y, Zhou H, Yan C, Yu F, et al. Novel Function of Extracellular Matrix Protein 1 in Suppressing Th17 Cell Development in Experimental Autoimmune Encephalomyelitis. J Immunol. 2016;197:1054-64 pubmed publisher |
Shin H, Kim H, Oh S, Lee J, Kee M, Ko H, et al. AMPK-SKP2-CARM1 signalling cascade in transcriptional regulation of autophagy. Nature. 2016;534:553-7 pubmed publisher |
Rowald K, Mantovan M, Passos J, Buccitelli C, Mardin B, Korbel J, et al. Negative Selection and Chromosome Instability Induced by Mad2 Overexpression Delay Breast Cancer but Facilitate Oncogene-Independent Outgrowth. Cell Rep. 2016;15:2679-91 pubmed publisher |
Gross G, Straub C, Perez Sanchez J, Dempsey W, Junge J, Roberts R, et al. An E3-ligase-based method for ablating inhibitory synapses. Nat Methods. 2016;13:673-8 pubmed publisher |
Fan R, Toubal A, Goñi S, Drareni K, Huang Z, Alzaid F, et al. Loss of the co-repressor GPS2 sensitizes macrophage activation upon metabolic stress induced by obesity and type 2 diabetes. Nat Med. 2016;22:780-91 pubmed publisher |
Lawson C, Fan C, Mitin N, Baker N, George S, Graham D, et al. Rho GTPase Transcriptome Analysis Reveals Oncogenic Roles for Rho GTPase-Activating Proteins in Basal-like Breast Cancers. Cancer Res. 2016;76:3826-37 pubmed publisher |
Veit G, Oliver K, Apaja P, Perdomo D, Bidaud Meynard A, Lin S, et al. Ribosomal Stalk Protein Silencing Partially Corrects the ΔF508-CFTR Functional Expression Defect. PLoS Biol. 2016;14:e1002462 pubmed publisher |
Aldrin Kirk P, Heuer A, Wang G, Mattsson B, Lundblad M, Parmar M, et al. DREADD Modulation of Transplanted DA Neurons Reveals a Novel Parkinsonian Dyskinesia Mechanism Mediated by the Serotonin 5-HT6 Receptor. Neuron. 2016;90:955-68 pubmed publisher |
Nam H, Lee S. Identification of STAM1 as a novel effector of ventral projection of spinal motor neurons. Development. 2016;143:2334-43 pubmed publisher |
Douchi D, Qu Y, Longoni P, Legendre Lefebvre L, Johnson X, Schmitz Linneweber C, et al. A Nucleus-Encoded Chloroplast Phosphoprotein Governs Expression of the Photosystem I Subunit PsaC in Chlamydomonas reinhardtii. Plant Cell. 2016;28:1182-99 pubmed publisher |
Alagramam K, Gopal S, Geng R, Chen D, Nemet I, Lee R, et al. A small molecule mitigates hearing loss in a mouse model of Usher syndrome III. Nat Chem Biol. 2016;12:444-51 pubmed publisher |
Aaes T, Kaczmarek A, Delvaeye T, De Craene B, De Koker S, Heyndrickx L, et al. Vaccination with Necroptotic Cancer Cells Induces Efficient Anti-tumor Immunity. Cell Rep. 2016;15:274-87 pubmed publisher |
Starokadomskyy P, Gemelli T, Rios J, Xing C, Wang R, Li H, et al. DNA polymerase-? regulates the activation of type I interferons through cytosolic RNA:DNA synthesis. Nat Immunol. 2016;17:495-504 pubmed publisher |
Padilla S, Qiu J, Soden M, Sanz E, Nestor C, Barker F, et al. Agouti-related peptide neural circuits mediate adaptive behaviors in the starved state. Nat Neurosci. 2016;19:734-41 pubmed publisher |
Thongthip S, Bellani M, Gregg S, Sridhar S, Conti B, Chen Y, et al. Fan1 deficiency results in DNA interstrand cross-link repair defects, enhanced tissue karyomegaly, and organ dysfunction. Genes Dev. 2016;30:645-59 pubmed publisher |
Lee B, Lee S, Agulnick A, Lee J, Lee S. Single-stranded DNA binding proteins are required for LIM complexes to induce transcriptionally active chromatin and specify spinal neuronal identities. Development. 2016;143:1721-31 pubmed publisher |
Mitxelena J, Apraiz A, Vallejo RodrÃguez J, Malumbres M, Zubiaga A. E2F7 regulates transcription and maturation of multiple microRNAs to restrain cell proliferation. Nucleic Acids Res. 2016;: pubmed |
Matak P, Matak A, Moustafa S, Aryal D, Benner E, Wetsel W, et al. Disrupted iron homeostasis causes dopaminergic neurodegeneration in mice. Proc Natl Acad Sci U S A. 2016;113:3428-35 pubmed publisher |
Hodge C, Ismail I, Edwards R, Hura G, Xiao A, Tainer J, et al. RNF8 E3 Ubiquitin Ligase Stimulates Ubc13 E2 Conjugating Activity That Is Essential for DNA Double Strand Break Signaling and BRCA1 Tumor Suppressor Recruitment. J Biol Chem. 2016;291:9396-410 pubmed publisher |
Lehmann W, Mossmann D, Kleemann J, Mock K, Meisinger C, Brummer T, et al. ZEB1 turns into a transcriptional activator by interacting with YAP1 in aggressive cancer types. Nat Commun. 2016;7:10498 pubmed publisher |
Sousa Martins J, Liu X, Oke A, Arora R, Franciosi F, Viville S, et al. DAZL and CPEB1 regulate mRNA translation synergistically during oocyte maturation. J Cell Sci. 2016;129:1271-82 pubmed publisher |
RodrÃguez Escudero M, Cid V, Molina M, Schulze Luehrmann J, Lührmann A, RodrÃguez Escudero I. Studying Coxiella burnetii Type IV Substrates in the Yeast Saccharomyces cerevisiae: Focus on Subcellular Localization and Protein Aggregation. PLoS ONE. 2016;11:e0148032 pubmed publisher |
Liu Z, Li X, Zhang J, Cai Y, Cheng T, Cheng C, et al. Autism-like behaviours and germline transmission in transgenic monkeys overexpressing MeCP2. Nature. 2016;530:98-102 pubmed publisher |
Testoni E, Stephenson N, Torres Ayuso P, Marusiak A, Trotter E, Hudson A, et al. Somatically mutated ABL1 is an actionable and essential NSCLC survival gene. EMBO Mol Med. 2016;8:105-16 pubmed publisher |
Kim Y, Nam H, Lee J, Park D, Kim C, Yu Y, et al. Methylation-dependent regulation of HIF-1α stability restricts retinal and tumour angiogenesis. Nat Commun. 2016;7:10347 pubmed publisher |
Thoms M, Ahmed Y, Maddi K, Hurt E, Sinning I. Concerted removal of the Erb1-Ytm1 complex in ribosome biogenesis relies on an elaborate interface. Nucleic Acids Res. 2016;44:926-39 pubmed publisher |
Wilson C, Chang A, Greene R, Machado S, Parsons M, Takats T, et al. Knockdown of Inner Arm Protein IC138 in Trypanosoma brucei Causes Defective Motility and Flagellar Detachment. PLoS ONE. 2015;10:e0139579 pubmed publisher |
Morozumi Y, Boussouar F, Tan M, Chaikuad A, Jamshidikia M, Colak G, et al. Atad2 is a generalist facilitator of chromatin dynamics in embryonic stem cells. J Mol Cell Biol. 2016;8:349-62 pubmed publisher |
Görtz D, Braun G, Maruta Y, Djudjaj S, van Roeyen C, Martin I, et al. Anti-interleukin-6 therapy through application of a monogenic protein inhibitor via gene delivery. Sci Rep. 2015;5:14685 pubmed publisher |
Hogarth C, Evans E, Onken J, Kent T, Mitchell D, Petkovich M, et al. CYP26 Enzymes Are Necessary Within the Postnatal Seminiferous Epithelium for Normal Murine Spermatogenesis. Biol Reprod. 2015;93:19 pubmed publisher |
Smith B, Shelton D, Kieffer C, Milash B, Usary J, Perou C, et al. Targeting the PyMT Oncogene to Diverse Mammary Cell Populations Enhances Tumor Heterogeneity and Generates Rare Breast Cancer Subtypes. Genes Cancer. 2012;3:550-63 pubmed publisher |
