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- immunohistochemistry; human; fig 1b
| de Jong J, Llapashtica C, Genestine M, Strauss K, Provenzano F, Sun Y, et al. Cortical overgrowth in a preclinical forebrain organoid model of CNTNAP2-associated autism spectrum disorder. Nat Commun. 2021;12:4087 pubmed publisher
|
- immunohistochemistry; mouse; 1:500; loading ...; fig 3h
| Quintana Urzainqui I, Hernández Malmierca P, Clegg J, Li Z, Kozic Z, Price D. The role of the diencephalon in the guidance of thalamocortical axons in mice. Development. 2020;147: pubmed publisher
|
| Gracia Diaz C, Zhou Y, Yang Q, Maroofian R, Espana Bonilla P, Lee C, et al. Gain and loss of function variants in EZH1 disrupt neurogenesis and cause dominant and recessive neurodevelopmental disorders. Nat Commun. 2023;14:4109 pubmed publisher
|
| Rybak Wolf A, Wyler E, Pentimalli T, Legnini I, Oliveras Martinez A, Gla x17e ar P, et al. Modelling viral encephalitis caused by herpes simplex virus 1 infection in cerebral organoids. Nat Microbiol. 2023;8:1252-1266 pubmed publisher
|
| Cappuccio G, Khalil S, Osenberg S, Li F, Maletic Savatic M. Mass spectrometry imaging as an emerging tool for studying metabolism in human brain organoids. Front Mol Biosci. 2023;10:1181965 pubmed publisher
|
| Eigenhuis K, Somsen H, van der Kroeg M, Smeenk H, Korporaal A, Kushner S, et al. A simplified protocol for the generation of cortical brain organoids. Front Cell Neurosci. 2023;17:1114420 pubmed publisher
|
| Xu A, Liu M, Huang M, Zhang Y, Hu R, Gingold J, et al. Rewired m6A epitranscriptomic networks link mutant p53 to neoplastic transformation. Nat Commun. 2023;14:1694 pubmed publisher
|
| Guo C, Cao X, Zhang Y, Yue K, Han J, Yan H, et al. Exosome-mediated inhibition of microRNA-449a promotes the amplification of mouse retinal progenitor cells and enhances their transplantation in retinal degeneration mouse models. Mol Ther Nucleic Acids. 2023;31:763-778 pubmed publisher
|
| Li B, Zhao H, Tu Z, Yang W, Han R, Wang L, et al. CHD8 mutations increase gliogenesis to enlarge brain size in the nonhuman primate. Cell Discov. 2023;9:27 pubmed publisher
|
| Loan A, Leung J, Cook D, Ko C, Vanderhyden B, Wang J, et al. Prenatal low-dose methylmercury exposure causes premature neuronal differentiation and autism-like behaviors in a rodent model. iScience. 2023;26:106093 pubmed publisher
|
| Dong Z, He W, Lin G, Chen X, Cao S, Guan T, et al. Histone acetyltransferase KAT2A modulates neural stem cell differentiation and proliferation by inducing degradation of the transcription factor PAX6. J Biol Chem. 2023;299:103020 pubmed publisher
|
| Cheng Q, Wu J, Xia Y, Cheng Q, Zhao Y, Zhu P, et al. Disruption of protein geranylgeranylation in the cerebellum causes cerebellar hypoplasia and ataxia via blocking granule cell progenitor proliferation. Mol Brain. 2023;16:24 pubmed publisher
|
| Xue W, Liu H, Xiao Y, Li B, Ren L, Li H, et al. Generation of dorsoventral human spinal cord organoids via functionalizing composite scaffold for drug testing. iScience. 2023;26:105898 pubmed publisher
|
| Whye D, Wood D, Saber W, Norabuena E, Makhortova N, Sahin M, et al. A Robust Pipeline for the Multi-Stage Accelerated Differentiation of Functional 3D Cortical Organoids from Human Pluripotent Stem Cells. Curr Protoc. 2023;3:e641 pubmed publisher
|
| Sterling N, Park J, Park R, Cho S, Kim S. An entosis-like process induces mitotic disruption in Pals1 microcephaly pathogenesis. Nat Commun. 2023;14:82 pubmed publisher
|
| Chen X, Momin A, Wanggou S, Wang X, Min H, Dou W, et al. Mechanosensitive brain tumor cells construct blood-tumor barrier to mask chemosensitivity. Neuron. 2023;111:30-48.e14 pubmed publisher
|
| Tristan C, Hong H, Jethmalani Y, Chen Y, Weber C, Chu P, et al. Efficient and safe single-cell cloning of human pluripotent stem cells using the CEPT cocktail. Nat Protoc. 2023;18:58-80 pubmed publisher
|
| Zhong Z, Chen S. Isolation and Expansion of Primary Conjunctival Stem Cells (CjSCs) from Human and Rabbit Tissues. Bio Protoc. 2022;12: pubmed publisher
|
| Kokorudz C, Radford B, Dean W, Hemberger M. Advanced Maternal Age Differentially Affects Embryonic Tissues with the Most Severe Impact on the Developing Brain. Cells. 2022;12: pubmed publisher
|
| Ferdaos N, Lowell S, Mason J. Pax6 mutant cerebral organoids partially recapitulate phenotypes of Pax6 mutant mouse strains. PLoS ONE. 2022;17:e0278147 pubmed publisher
|
| Chen X, Saiyin H, Liu Y, Wang Y, Li X, Ji R, et al. Human striatal organoids derived from pluripotent stem cells recapitulate striatal development and compartments. PLoS Biol. 2022;20:e3001868 pubmed publisher
|
| Krach F, Stemick J, Boerstler T, Weiss A, Lingos I, Reischl S, et al. An alternative splicing modulator decreases mutant HTT and improves the molecular fingerprint in Huntington's disease patient neurons. Nat Commun. 2022;13:6797 pubmed publisher
|
| Ma L, Mei Y, Xu P, Cheng Y, You Z, Ji X, et al. Fast generation of forebrain oligodendrocyte spheroids from human embryonic stem cells by transcription factors. iScience. 2022;25:105172 pubmed publisher
|
| Metzger J, Pereda C, Adhikari A, Haremaki T, Galgoczi S, Siggia E, et al. Deep-learning analysis of micropattern-based organoids enables high-throughput drug screening of Huntington's disease models. Cell Rep Methods. 2022;2:100297 pubmed publisher
|
| Hendrikse L, Haldipur P, Saulnier O, Millman J, Sjoboen A, Erickson A, et al. Failure of human rhombic lip differentiation underlies medulloblastoma formation. Nature. 2022;609:1021-1028 pubmed publisher
|
| Schr xf6 ter M, Wang C, Terrigno M, Hornauer P, Huang Z, Jagasia R, et al. Functional imaging of brain organoids using high-density microelectrode arrays. MRS Bull. 2022;47:530-544 pubmed publisher
|
| Wang L, Park J, Liu F, Olesen K, Hou S, Peng J, et al. A kinase-independent function of cyclin-dependent kinase 6 promotes outer radial glia expansion and neocortical folding. Proc Natl Acad Sci U S A. 2022;119:e2206147119 pubmed publisher
|
| Tarazi S, Aguilera Castrejon A, Joubran C, Ghanem N, Ashouokhi S, Roncato F, et al. Post-gastrulation synthetic embryos generated ex utero from mouse naive ESCs. Cell. 2022;185:3290-3306.e25 pubmed publisher
|
| Jia X, Zhang S, Tan S, Du B, He M, Qin H, et al. De novo variants in genes regulating stress granule assembly associate with neurodevelopmental disorders. Sci Adv. 2022;8:eabo7112 pubmed publisher
|
| Yang Y, Laterza C, Stuart H, Michielin F, Gagliano O, Urciuolo A, et al. Human Pluripotent Stem Cell-Derived Micropatterned Ectoderm Allows Cell Sorting of Meso-Endoderm Lineages. Front Bioeng Biotechnol. 2022;10:907159 pubmed publisher
|
| Wang S, Fu Y, Miyata T, Matsumoto S, Shinoda T, Itoh K, et al. Functional Cooperation of α-Synuclein and Tau Is Essential for Proper Corticogenesis. J Neurosci. 2022;42:7031-7046 pubmed publisher
|
| Yao X, Lu Z, Feng Z, Gao L, Zhou X, Li M, et al. Comparison of chromatin accessibility landscapes during early development of prefrontal cortex between rhesus macaque and human. Nat Commun. 2022;13:3883 pubmed publisher
|
| Habib K, Bishayee K, Kang J, Sadra A, Huh S. RNA Binding Protein Rbms1 Enables Neuronal Differentiation and Radial Migration during Neocortical Development by Binding and Stabilizing the RNA Message for Efr3a. Mol Cells. 2022;: pubmed publisher
|
| Zhang Y, Li X, Cao X, Ji C, Gao X, Gao D, et al. MicroRNA-582-5p Contributes to the Maintenance of Neural Stem Cells Through Inhibiting Secretory Protein FAM19A1. Front Cell Neurosci. 2022;16:866020 pubmed publisher
|
| Zhang X, Huo H, Zhu Y, Feng H, Jiao J, Tan J, et al. Folic Acid Rescues Valproic Acid-Induced Morphogenesis Inhibition in Neural Rosettes Derived From Human Pluripotent Stem Cells. Front Cell Neurosci. 2022;16:888152 pubmed publisher
|
| Chao J, Feng L, Ye P, Chen X, Cui Q, Sun G, et al. Therapeutic development for Canavan disease using patient iPSCs introduced with the wild-type ASPA gene. iScience. 2022;25:104391 pubmed publisher
|
| Nieto Est xe9 vez V, Donegan J, McMahon C, Elam H, Chavera T, Varma P, et al. Buprenorphine Exposure Alters the Development and Migration of Interneurons in the Cortex. Front Mol Neurosci. 2022;15:889922 pubmed publisher
|
| Romero D, Poirier K, Belvindrah R, Moutkine I, Houllier A, LeMoing A, et al. Novel role of the synaptic scaffold protein Dlgap4 in ventricular surface integrity and neuronal migration during cortical development. Nat Commun. 2022;13:2746 pubmed publisher
|
| Schembs L, Willems A, Hasenpusch Theil K, Cooper J, Whiting K, Burr K, et al. The ciliary gene INPP5E confers dorsal telencephalic identity to human cortical organoids by negatively regulating Sonic hedgehog signaling. Cell Rep. 2022;39:110811 pubmed publisher
|
| Gallo R, Qureshi F, Strong T, Lang S, Pino K, Dvoriantchikova G, et al. Derivation and Characterization of Murine and Amphibian Müller Glia Cell Lines. Transl Vis Sci Technol. 2022;11:4 pubmed publisher
|
| Bro x17c ko N, Baggio S, Lipiec M, Jankowska M, Szewczyk x, Gabriel M, et al. Genoarchitecture of the Early Postmitotic Pretectum and the Role of Wnt Signaling in Shaping Pretectal Neurochemical Anatomy in Zebrafish. Front Neuroanat. 2022;16:838567 pubmed publisher
|
| Jabali A, Hoffrichter A, Uzquiano A, Marsoner F, Wilkens R, Siekmann M, et al. Human cerebral organoids reveal progenitor pathology in EML1-linked cortical malformation. EMBO Rep. 2022;23:e54027 pubmed publisher
|
| Lorenz C, Zink A, Henke M, Staege S, Mlody B, Bünning M, et al. Generation of four iPSC lines from four patients with Leigh syndrome carrying homoplasmic mutations m.8993T > G or m.8993T > C in the mitochondrial gene MT-ATP6. Stem Cell Res. 2022;61:102742 pubmed publisher
|
| Zhu X, Guo Y, Chu C, Liu D, Duan K, Yin Y, et al. BRN2 as a key gene drives the early primate telencephalon development. Sci Adv. 2022;8:eabl7263 pubmed publisher
|
| Soubannier V, Chaineau M, Gursu L, Haghi G, Franco Flores A, Rouleau G, et al. Rapid Generation of Ventral Spinal Cord-like Astrocytes from Human iPSCs for Modeling Non-Cell Autonomous Mechanisms of Lower Motor Neuron Disease. Cells. 2022;11: pubmed publisher
|
| LaForce G, Farr J, Liu J, Akesson C, Gumus E, Pinkard O, et al. Suppression of premature transcription termination leads to reduced mRNA isoform diversity and neurodegeneration. Neuron. 2022;110:1340-1357.e7 pubmed publisher
|
| Torsahakul C, Israsena N, Khramchantuk S, Ratanavaraporn J, Dhitavat S, Rodprasert W, et al. Bio-fabrication of stem-cell-incorporated corneal epithelial and stromal equivalents from silk fibroin and gelatin-based biomaterial for canine corneal regeneration. PLoS ONE. 2022;17:e0263141 pubmed publisher
|
| Avil xe9 s E, Krol A, Henle S, Burroughs Garcia J, Deans M, Goodrich L. Fat3 acts through independent cytoskeletal effectors to coordinate asymmetric cell behaviors during polarized circuit assembly. Cell Rep. 2022;38:110307 pubmed publisher
|
| Manos J, Preiss C, Venkat N, Tamm J, Reinhardt P, Kwon T, et al. Uncovering specificity of endogenous TAU aggregation in a human iPSC-neuron TAU seeding model. iScience. 2022;25:103658 pubmed publisher
|
| Muralidharan H, Guha S, Madugula K, Patil A, Bennison S, Sun X, et al. KIFC1 Regulates the Trajectory of Neuronal Migration. J Neurosci. 2022;42:2149-2165 pubmed publisher
|
| Le Floch P, Li Q, Lin Z, Zhao S, Liu R, Tasnim K, et al. Stretchable Mesh Nanoelectronics for 3D Single-Cell Chronic Electrophysiology from Developing Brain Organoids. Adv Mater. 2022;34:e2106829 pubmed publisher
|
| Carpentieri J, Di Cicco A, Lampič M, Andreau D, Del Maestro L, el Marjou F, et al. Endosomal trafficking defects alter neural progenitor proliferation and cause microcephaly. Nat Commun. 2022;13:16 pubmed publisher
|
| Han X, Shen X, Wang M, Wang X, Jian Y, Yang C, et al. Loss of RNA-Binding Protein HuR Leads to Defective Ependymal Cells and Hydrocephalus. J Neurosci. 2022;42:202-219 pubmed publisher
|
| Notaras M, Lodhi A, Dündar F, Collier P, Sayles N, Tilgner H, et al. Schizophrenia is defined by cell-specific neuropathology and multiple neurodevelopmental mechanisms in patient-derived cerebral organoids. Mol Psychiatry. 2022;27:1416-1434 pubmed publisher
|
| Nieto Estévez V, Changarathil G, Adeyeye A, Coppin M, Kassim R, Zhu J, et al. HDAC1 Regulates Neuronal Differentiation. Front Mol Neurosci. 2021;14:815808 pubmed publisher
|
| Klein J, Li Z, Rampam S, Cardini J, Ayoub A, Shaw P, et al. Sonic Hedgehog Pathway Modulation Normalizes Expression of Olig2 in Rostrally Patterned NPCs With Trisomy 21. Front Cell Neurosci. 2021;15:794675 pubmed publisher
|
| Vajhøj C, Schmid B, Alik A, Melki R, Fog K, Holst B, et al. Establishment of a human induced pluripotent stem cell neuronal model for identification of modulators of A53T α-synuclein levels and aggregation. PLoS ONE. 2021;16:e0261536 pubmed publisher
|
| Behesti H, Kocabas A, Buchholz D, Carroll T, Hatten M. Altered temporal sequence of transcriptional regulators in the generation of human cerebellar granule cells. elife. 2021;10: pubmed publisher
|
| Bockaj I, Martini T, de Camargo Magalhães E, Bakker P, Meeuwsen de Boer T, Armandari I, et al. The H3.3K27M oncohistone affects replication stress outcome and provokes genomic instability in pediatric glioma. PLoS Genet. 2021;17:e1009868 pubmed publisher
|
| Marinopoulou E, Biga V, Sabherwal N, Miller A, Desai J, Adamson A, et al. HES1 protein oscillations are necessary for neural stem cells to exit from quiescence. iScience. 2021;24:103198 pubmed publisher
|
| Marczenke M, Sunaga Franze D, Popp O, Althaus I, Sauer S, Mertins P, et al. GAS1 is required for NOTCH-dependent facilitation of SHH signaling in the ventral forebrain neuroepithelium. Development. 2021;148: pubmed publisher
|
| Li J, Chen L, Li D, Lu M, Huang X, Han X, et al. Electroacupuncture Promotes the Survival of the Grafted Human MGE Neural Progenitors in Rats with Cerebral Ischemia by Promoting Angiogenesis and Inhibiting Inflammation. Neural Plast. 2021;2021:4894881 pubmed publisher
|
| Junqueira Alves C, Dariolli R, Haydak J, Kang S, Hannah T, Wiener R, et al. Plexin-B2 orchestrates collective stem cell dynamics via actomyosin contractility, cytoskeletal tension and adhesion. Nat Commun. 2021;12:6019 pubmed publisher
|
| Penna E, Cunningham C, Saylor S, Kreutz A, Tarantal A, Mart xed nez Cerde xf1 o V, et al. Greater Number of Microglia in Telencephalic Proliferative Zones of Human and Nonhuman Primate Compared with Other Vertebrate Species. Cereb Cortex Commun. 2021;2:tgab053 pubmed publisher
|
| Taniguchi Ikeda M, Koyanagi Aoi M, Maruyama T, Takaori T, Hosoya A, Tezuka H, et al. Restoration of the defect in radial glial fiber migration and cortical plate organization in a brain organoid model of Fukuyama muscular dystrophy. iScience. 2021;24:103140 pubmed publisher
|
| Ziffra R, Kim C, Ross J, Wilfert A, Turner T, Haeussler M, et al. Single-cell epigenomics reveals mechanisms of human cortical development. Nature. 2021;598:205-213 pubmed publisher
|
| Meng Y, Zhang T, Zheng R, Ding S, Yang J, Liu R, et al. Depletion of Demethylase KDM6 Enhances Early Neuroectoderm Commitment of Human PSCs. Front Cell Dev Biol. 2021;9:702462 pubmed publisher
|
| Liu X, Dai S, Liu P, Liu C. Arid1a regulates neural stem/progenitor cell proliferation and differentiation during cortical development. Cell Prolif. 2021;54:e13124 pubmed publisher
|
| Wind M, Tsakiridis A. In Vitro Generation of Posterior Motor Neurons from Human Pluripotent Stem Cells. Curr Protoc. 2021;1:e244 pubmed publisher
|
| Popova G, Soliman S, Kim C, Keefe M, Hennick K, Jain S, et al. Human microglia states are conserved across experimental models and regulate neural stem cell responses in chimeric organoids. Cell Stem Cell. 2021;28:2153-2166.e6 pubmed publisher
|
| Girskis K, Stergachis A, DeGennaro E, Doan R, Qian X, Johnson M, et al. Rewiring of human neurodevelopmental gene regulatory programs by human accelerated regions. Neuron. 2021;109:3239-3251.e7 pubmed publisher
|
| Walker H, Taiyab A, Deschamps P, Williams T, West Mays J. Conditional Deletion of AP-2β in the Periocular Mesenchyme of Mice Alters Corneal Epithelial Cell Fate and Stratification. Int J Mol Sci. 2021;22: pubmed publisher
|
| Viais R, Fariña Mosquera M, Villamor Payà M, Watanabe S, Palenzuela L, Lacasa C, et al. Augmin deficiency in neural stem cells causes p53-dependent apoptosis and aborts brain development. elife. 2021;10: pubmed publisher
|
| Zhong D, Zhang Y, Zhang S, Ge Y, Tong M, Feng Y, et al. Adenosine A2A receptor antagonism protects against hyperoxia-induced retinal vascular loss via cellular proliferation. FASEB J. 2021;35:e21842 pubmed publisher
|
| Usman A, Haase A, Merkert S, Göhring G, Hansmann G, Gall H, et al. Generation of pulmonary arterial hypertension patient-specific induced pluripotent stem cell lines from three unrelated patients with a heterozygous missense mutation in exon 12, a heterozygous in-frame deletion in exon 3 and a missense mutation in e. Stem Cell Res. 2021;55:102488 pubmed publisher
|
| Arnst N, Belio Mairal P, García González L, Arnaud L, Greetham L, Nivet E, et al. Deficiency in MT5-MMP Supports Branching of Human iPSCs-Derived Neurons and Reduces Expression of GLAST/S100 in iPSCs-Derived Astrocytes. Cells. 2021;10: pubmed publisher
|
| Haldipur P, Bernardo S, Aldinger K, Sivakumar T, Millman J, Sjoboen A, et al. Evidence of disrupted rhombic lip development in the pathogenesis of Dandy-Walker malformation. Acta Neuropathol. 2021;142:761-776 pubmed publisher
|
| Hwang S, Somatilaka B, White K, Mukhopadhyay S. Ciliary and extraciliary Gpr161 pools repress hedgehog signaling in a tissue-specific manner. elife. 2021;10: pubmed publisher
|
| Bowles K, Silva M, Whitney K, Bertucci T, Berlind J, Lai J, et al. ELAVL4, splicing, and glutamatergic dysfunction precede neuron loss in MAPT mutation cerebral organoids. Cell. 2021;184:4547-4563.e17 pubmed publisher
|
| Barra J, Kozlovskaya V, Kepple J, Seeberger K, Kuppan P, Hunter C, et al. Xenotransplantation of tannic acid-encapsulated neonatal porcine islets decreases proinflammatory innate immune responses. Xenotransplantation. 2021;28:e12706 pubmed publisher
|
| Martens Y, Xu S, Tait R, Li G, Zhao X, Lu W, et al. Generation and validation of APOE knockout human iPSC-derived cerebral organoids. STAR Protoc. 2021;2:100571 pubmed publisher
|
| Kaufman M, Goodson N, Park K, Schwanke M, Office E, Schneider S, et al. Initiation of Otx2 expression in the developing mouse retina requires a unique enhancer and either Ascl1 or Neurog2 activity. Development. 2021;148: pubmed publisher
|
| Aldinger K, Thomson Z, Phelps I, Haldipur P, Deng M, Timms A, et al. Spatial and cell type transcriptional landscape of human cerebellar development. Nat Neurosci. 2021;24:1163-1175 pubmed publisher
|
| Kalusa M, Heinrich M, Sauerland C, Morawski M, Fietz S. Developmental Differences in Neocortex Neurogenesis and Maturation Between the Altricial Dwarf Rabbit and Precocial Guinea Pig. Front Neuroanat. 2021;15:678385 pubmed publisher
|
| Gao X, Li G, Deng H, Feng W, Li Y, Liu M, et al. Generation of an iPSC line (GWCMCi002-A) from an X-linked Alport syndrome patient with a hemizygous splicing mutation (NM_000495.4, c. 1517-1 G > T) in the COL4A5 gene. Stem Cell Res. 2021;53:102388 pubmed publisher
|
| Li J, Wu K, Guan J, Wang Q, Wang H. Generation of a human induced pluripotent stem cell line (CPGHi003-A) from an auditory neuropathy patient with AIFM1 p.R422Q mutation. Stem Cell Res. 2021;53:102376 pubmed publisher
|
| Jia N, Gong X, Chen J, Yang T, Bao C, Shen J, et al. Generation of an induced pluripotent stem cell line (OGHFUi001-A) from a type 1 early infantile epileptic encephalopathy with ARX mutation. Stem Cell Res. 2021;53:102367 pubmed publisher
|
| Yu Q, Biswas S, Ma G, Zhao P, Li B, Li J. Canonical NF-κB signaling maintains corneal epithelial integrity and prevents corneal aging via retinoic acid. elife. 2021;10: pubmed publisher
|
| Mathieu C, Bovier F, Ferren M, Lieberman N, Predella C, Lalande A, et al. Molecular Features of the Measles Virus Viral Fusion Complex That Favor Infection and Spread in the Brain. MBio. 2021;12:e0079921 pubmed publisher
|
| Takahashi K, Nakamura M, Okubo C, Kliesmete Z, Ohnuki M, Narita M, et al. The pluripotent stem cell-specific transcript ESRG is dispensable for human pluripotency. PLoS Genet. 2021;17:e1009587 pubmed publisher
|
| Žagare A, Gobin M, Monzel A, Schwamborn J. A robust protocol for the generation of human midbrain organoids. STAR Protoc. 2021;2:100524 pubmed publisher
|
| Liang D, Elwell A, Aygün N, Krupa O, Wolter J, Kyere F, et al. Cell-type-specific effects of genetic variation on chromatin accessibility during human neuronal differentiation. Nat Neurosci. 2021;24:941-953 pubmed publisher
|
| Nakashima H, Tsujimura K, Irie K, Imamura T, Trujillo C, Ishizu M, et al. MeCP2 controls neural stem cell fate specification through miR-199a-mediated inhibition of BMP-Smad signaling. Cell Rep. 2021;35:109124 pubmed publisher
|
| Hou S, Ho W, Wang L, Kuo B, Park J, Han Y. Biphasic Roles of Hedgehog Signaling in the Production and Self-Renewal of Outer Radial Glia in the Ferret Cerebral Cortex. Cereb Cortex. 2021;31:4730-4741 pubmed publisher
|
| Padmanabhan Nair V, Liu H, Ciceri G, Jungverdorben J, Frishman G, Tchieu J, et al. Activation of HERV-K(HML-2) disrupts cortical patterning and neuronal differentiation by increasing NTRK3. Cell Stem Cell. 2021;28:1566-1581.e8 pubmed publisher
|
| Chen Y, Tristan C, Chen L, Jovanovic V, Malley C, Chu P, et al. A versatile polypharmacology platform promotes cytoprotection and viability of human pluripotent and differentiated cells. Nat Methods. 2021;18:528-541 pubmed publisher
|
| Ezan J, Moreau M, Mamo T, Shimbo M, Decroo M, Richter M, et al. Early loss of Scribble affects cortical development, interhemispheric connectivity and psychomotor activity. Sci Rep. 2021;11:9106 pubmed publisher
|
| Ramme A, Faust D, Koenig L, Nguyen N, Marx U. Generation of two additional integration-free iPSC lines from related human donors. Stem Cell Res. 2021;53:102327 pubmed publisher
|
| Li Y, Deng W, Jin Z. Modeling retinitis pigmentosa through patient-derived retinal organoids. STAR Protoc. 2021;2:100438 pubmed publisher
|
| Li N, Lin S, Li Y, Sun J, Zhang L, Chen M. An induced pluripotent stem cell line (GZHMCi004-A) derived from a fetus with heterozygous G380R mutation in FGFR3 gene causing achondroplasia. Stem Cell Res. 2021;53:102322 pubmed publisher
|
| Prince L, Neely M, Warren E, Thomas M, Henley M, Smith K, et al. Environmentally relevant developmental methylmercury exposures alter neuronal differentiation in a human-induced pluripotent stem cell model. Food Chem Toxicol. 2021;152:112178 pubmed publisher
|
| Ma L, Wu Z, Tang Q, Ji X, Mei Y, Peng T, et al. Generation of an induced pluripotent stem cell line from a patient with global development delay carrying DYRK1A mutation (c.1730T>A) and a gene correction isogenic iPSC line. Stem Cell Res. 2021;53:102305 pubmed publisher
|
| Schinzel F, Seyfer H, Ebbers L, Nothwang H. The Lbx1 lineage differentially contributes to inhibitory cell types of the dorsal cochlear nucleus, a cerebellum-like structure, and the cerebellum. J Comp Neurol. 2021;529:3032-3045 pubmed publisher
|
| Inak G, Rybak Wolf A, Lisowski P, Pentimalli T, Jüttner R, Glažar P, et al. Defective metabolic programming impairs early neuronal morphogenesis in neural cultures and an organoid model of Leigh syndrome. Nat Commun. 2021;12:1929 pubmed publisher
|
| Bannier Hélaouët M, Post Y, Korving J, Trani Bustos M, Gehart H, Begthel H, et al. Exploring the human lacrimal gland using organoids and single-cell sequencing. Cell Stem Cell. 2021;28:1221-1232.e7 pubmed publisher
|
| Eze U, Bhaduri A, Haeussler M, Nowakowski T, Kriegstein A. Single-cell atlas of early human brain development highlights heterogeneity of human neuroepithelial cells and early radial glia. Nat Neurosci. 2021;24:584-594 pubmed publisher
|
| Gao X, Qiu S, Wang W, Kang D, Su N, Dai P, et al. Generation of a gene corrected human isogenic iPSC line (CPGHi002-A-1) from a DDOD patient with heterozygous c.1516 C>T mutation in the ATP6V1B2 gene. Stem Cell Res. 2021;53:102271 pubmed publisher
|
| Fischer M, Chander P, Kang H, Mellios N, Weick J. Transcriptomic changes due to early, chronic intermittent alcohol exposure during forebrain development implicate WNT signaling, cell-type specification, and cortical regionalization as primary determinants of fetal alcohol syndrome. Alcohol Clin Exp Res. 2021;45:979-995 pubmed publisher
|
| Tolomeo A, Laterza C, Grespan E, Michielin F, Canals I, Kokaia Z, et al. NGN2 mmRNA-Based Transcriptional Programming in Microfluidic Guides hiPSCs Toward Neural Fate With Multiple Identities. Front Cell Neurosci. 2021;15:602888 pubmed publisher
|
| Kweon H, Jung W, Im G, Ryoo J, Lee J, Do H, et al. Excitatory neuronal CHD8 in the regulation of neocortical development and sensory-motor behaviors. Cell Rep. 2021;34:108780 pubmed publisher
|
| Sun X, Zhou X, Dong B, Wang C, Xiao X, Wang Y. Generation of a gene-corrected isogenic iPSC line (AHQUi001-A-1) from a patient with familial hypertriglyceridemia (FHTG) carrying a heterozygous p.C310R (c.928 T > C) mutation in LPL gene using CRISPR/Cas9. Stem Cell Res. 2021;52:102230 pubmed publisher
|
| Merkert S, Wunderlich S, Beier J, Franke A, Schwanke K, Göhring G, et al. Generation of two iPSC clones (MHHi021-A and MHHi021-B) from a patient with hypertrophic cardiomyopathy with p.Arg723Gly mutation in the MYH7 gene. Stem Cell Res. 2021;52:102208 pubmed publisher
|
| Campbell W, Fritsch Kelleher A, Palazzo I, Hoang T, Blackshaw S, Fischer A. Midkine is neuroprotective and influences glial reactivity and the formation of Müller glia-derived progenitor cells in chick and mouse retinas. Glia. 2021;69:1515-1539 pubmed publisher
|
| Too L, Shen W, Mammo Z, Osaadon P, Gillies M, Simunovic M. SURGICAL RETINAL EXPLANTS AS A SOURCE OF RETINAL PROGENITOR CELLS. Retina. 2021;41:1986-1993 pubmed publisher
|
| Schmid B, Holst B, Clausen C, Bahnassawy L, Reinhardt P, Bakker M, et al. Generation of a set of isogenic iPSC lines carrying all APOE genetic variants (Ɛ2/Ɛ3/Ɛ4) and knock-out for the study of APOE biology in health and disease. Stem Cell Res. 2021;52:102180 pubmed publisher
|
| Kim T, Piao J, Koo S, Kriks S, Chung S, Betel D, et al. Biphasic Activation of WNT Signaling Facilitates the Derivation of Midbrain Dopamine Neurons from hESCs for Translational Use. Cell Stem Cell. 2021;28:343-355.e5 pubmed publisher
|
| Haag D, Mack N, Benites Goncalves da Silva P, Statz B, Clark J, Tanabe K, et al. H3.3-K27M drives neural stem cell-specific gliomagenesis in a human iPSC-derived model. Cancer Cell. 2021;: pubmed publisher
|
| Korecki A, Cueva Vargas J, Fornes O, Agostinone J, Farkas R, Hickmott J, et al. Human MiniPromoters for ocular-rAAV expression in ON bipolar, cone, corneal, endothelial, Müller glial, and PAX6 cells. Gene Ther. 2021;28:351-372 pubmed publisher
|
| Simsa R, Rothenb xfc cher T, G xfc rb xfc z H, Ghosheh N, Emneus J, Jenndahl L, et al. Brain organoid formation on decellularized porcine brain ECM hydrogels. PLoS ONE. 2021;16:e0245685 pubmed publisher
|
| Chen M, Lin S, Li N, Li Y, Li Y, Zhang L. An induced pluripotent stem cell line (GZHMCi003-A) derived from a fetus with exon 3 heterozygous deletion in RUNX2 gene causing cleidocranial dysplasia. Stem Cell Res. 2021;51:102166 pubmed publisher
|
| Li M, Huang H, Li L, He C, Zhu L, Guo H, et al. Core transcription regulatory circuitry orchestrates corneal epithelial homeostasis. Nat Commun. 2021;12:420 pubmed publisher
|
| Arber C, Lovejoy C, Harris L, Willumsen N, Alatza A, Casey J, et al. Familial Alzheimer's Disease Mutations in PSEN1 Lead to Premature Human Stem Cell Neurogenesis. Cell Rep. 2021;34:108615 pubmed publisher
|
| Li M, Zhu L, Liu J, Huang H, Guo H, Wang L, et al. Loss of FOXC1 contributes to the corneal epithelial fate switch and pathogenesis. Signal Transduct Target Ther. 2021;6:5 pubmed publisher
|
| Clark A, Zhu Z, Krach F, Rich J, Yeo G, Spector D. Zika virus is transmitted in neural progenitor cells via cell-to-cell spread and infection is inhibited by the autophagy inducer trehalose. J Virol. 2020;: pubmed publisher
|
| Kim H, Lee S, Lim J, Yoo J, Hwang D. The epidermal growth factor receptor variant type III mutation frequently found in gliomas induces astrogenesis in human cerebral organoids. Cell Prolif. 2021;54:e12965 pubmed publisher
|
| Ucuncu E, Rajamani K, Wilson M, Medina Cano D, Altin N, David P, et al. MINPP1 prevents intracellular accumulation of the chelator inositol hexakisphosphate and is mutated in Pontocerebellar Hypoplasia. Nat Commun. 2020;11:6087 pubmed publisher
|
| Chai G, Webb A, Li C, Antaki D, Lee S, Breuss M, et al. Mutations in Spliceosomal Genes PPIL1 and PRP17 Cause Neurodegenerative Pontocerebellar Hypoplasia with Microcephaly. Neuron. 2021;109:241-256.e9 pubmed publisher
|
| Freude K, Saruhanian S, McCauley A, Paterson C, Odette M, Oostenink A, et al. Enrichment of retinal ganglion and Müller glia progenitors from retinal organoids derived from human induced pluripotent stem cells - possibilities and current limitations. World J Stem Cells. 2020;12:1171-1183 pubmed publisher
|
| de Leeuw V, van Oostrom C, Imholz S, Piersma A, Hessel E, Dollé M. Going Back and Forth: Episomal Vector Reprogramming of Peripheral Blood Mononuclear Cells to Induced Pluripotent Stem Cells and Subsequent Differentiation into Cardiomyocytes and Neuron-Astrocyte Co-cultures. Cell Reprogram. 2020;22:300-310 pubmed publisher
|
| Ahn L, Coatti G, Liu J, Gumus E, Schaffer A, Miranda H. An epilepsy-associated ACTL6B variant captures neuronal hyperexcitability in a human induced pluripotent stem cell model. J Neurosci Res. 2021;99:110-123 pubmed publisher
|
| Li Z, Lang Y, Sakamuru S, Samrat S, Trudeau N, Kuo L, et al. Methylene blue is a potent and broad-spectrum inhibitor against Zika virus in vitro and in vivo. Emerg Microbes Infect. 2020;9:2404-2416 pubmed publisher
|
| Sun W, Ramirez S, Spiller K, Zhao Y, Fuhrmann S. Nf2 fine-tunes proliferation and tissue alignment during closure of the optic fissure in the embryonic mouse eye. Hum Mol Genet. 2020;29:3373-3387 pubmed publisher
|
| Yao H, Hannum D, Zhai Y, Hill S, Albanus R, Lou W, et al. CHD7 promotes neural progenitor differentiation in embryonic stem cells via altered chromatin accessibility and nascent gene expression. Sci Rep. 2020;10:17445 pubmed publisher
|
| Jeong D, Lozano Casasbuenas D, Gengatharan A, Edwards K, Saghatelyan A, Kaplan D, et al. LRIG1-Mediated Inhibition of EGF Receptor Signaling Regulates Neural Precursor Cell Proliferation in the Neocortex. Cell Rep. 2020;33:108257 pubmed publisher
|
| Besusso D, Cossu A, Mohamed A, Cernigoj M, Codega P, Galimberti M, et al. A CRISPR-strategy for the generation of a detectable fluorescent hESC reporter line (WAe009-A-37) for the subpallial determinant GSX2. Stem Cell Res. 2020;49:102016 pubmed publisher
|
| Gao X, Qiu S, Feng M, Huang S, Kang D, Han M, et al. Establishment of human induced pluripotent stem cell line (CPGHi002-A) from a 10-month-old female patient with DDOD syndrome carrying a heterozygous c.1516 C > T mutation in ATP6V1B2. Stem Cell Res. 2020;48:101986 pubmed publisher
|
| Li Z, Xu J, Lang Y, Fan X, Kuo L, D Brant L, et al. JMX0207, a Niclosamide Derivative with Improved Pharmacokinetics, Suppresses Zika Virus Infection Both In Vitro and In Vivo. ACS Infect Dis. 2020;6:2616-2628 pubmed publisher
|
| Hasenpusch Theil K, Laclef C, Colligan M, Fitzgerald E, Howe K, Carroll E, et al. A transient role of the ciliary gene Inpp5e in controlling direct versus indirect neurogenesis in cortical development. elife. 2020;9: pubmed publisher
|
| Sood S, Weber C, Hodges H, Krokhotin A, Shalizi A, Crabtree G. CHD8 dosage regulates transcription in pluripotency and early murine neural differentiation. Proc Natl Acad Sci U S A. 2020;117:22331-22340 pubmed publisher
|
| Tristan C, Ormanoglu P, Slamecka J, Malley C, Chu P, Jovanovic V, et al. Robotic High-Throughput Biomanufacturing and Functional Differentiation of Human Pluripotent Stem Cells. bioRxiv. 2020;: pubmed publisher
|
| Zhang L, Avery J, Yin A, Singh A, Cliff T, Yin H, et al. Generation of Functional Brown Adipocytes from Human Pluripotent Stem Cells via Progression through a Paraxial Mesoderm State. Cell Stem Cell. 2020;27:784-797.e11 pubmed publisher
|
| Lin L, Zhang M, Stoilov P, Chen L, Zheng S. Developmental Attenuation of Neuronal Apoptosis by Neural-Specific Splicing of Bak1 Microexon. Neuron. 2020;107:1180-1196.e8 pubmed publisher
|
| Pereiro X, Miltner A, La Torre A, Vecino E. Effects of Adult Müller Cells and Their Conditioned Media on the Survival of Stem Cell-Derived Retinal Ganglion Cells. Cells. 2020;9: pubmed publisher
|
| Somatilaka B, Hwang S, Palicharla V, White K, Badgandi H, Shelton J, et al. Ankmy2 Prevents Smoothened-Independent Hyperactivation of the Hedgehog Pathway via Cilia-Regulated Adenylyl Cyclase Signaling. Dev Cell. 2020;: pubmed publisher
|
| Tsai M, Cheng H, Nian F, Liu C, Chao N, Chiang K, et al. Impairment in dynein-mediated nuclear translocation by BICD2 C-terminal truncation leads to neuronal migration defect and human brain malformation. Acta Neuropathol Commun. 2020;8:106 pubmed publisher
|
| Yan P, Liu Z, Song M, Wu Z, Xu W, Li K, et al. Genome-wide R-loop Landscapes during Cell Differentiation and Reprogramming. Cell Rep. 2020;32:107870 pubmed publisher
|
| Birkhoff J, Brouwer R, Kolovos P, Korporaal A, Bermejo Santos A, Boltsis I, et al. Targeted chromatin conformation analysis identifies novel distal neural enhancers of ZEB2 in pluripotent stem cell differentiation. Hum Mol Genet. 2020;29:2535-2550 pubmed publisher
|
| Cederquist G, Tchieu J, Callahan S, Ramnarine K, Ryan S, Zhang C, et al. A Multiplex Human Pluripotent Stem Cell Platform Defines Molecular and Functional Subclasses of Autism-Related Genes. Cell Stem Cell. 2020;27:35-49.e6 pubmed publisher
|
| Urciuolo A, Poli I, Brandolino L, Raffa P, Scattolini V, Laterza C, et al. Intravital three-dimensional bioprinting. Nat Biomed Eng. 2020;4:901-915 pubmed publisher
|
| Patmore D, Jassim A, Nathan E, Gilbertson R, Tahan D, Hoffmann N, et al. DDX3X Suppresses the Susceptibility of Hindbrain Lineages to Medulloblastoma. Dev Cell. 2020;54:455-470.e5 pubmed publisher
|
| Xiao D, Deng Q, Guo Y, Huang X, Zou M, Zhong J, et al. Generation of self-organized sensory ganglion organoids and retinal ganglion cells from fibroblasts. Sci Adv. 2020;6:eaaz5858 pubmed publisher
|
| Gregory J, Hoelzli E, Abdelaal R, Braine C, Cuevas M, Halpern M, et al. Cell Type-Specific In Vitro Gene Expression Profiling of Stem Cell-Derived Neural Models. Cells. 2020;9: pubmed publisher
|
| Roy A, Millen K, Kapur R. Hippocampal granule cell dispersion: a non-specific finding in pediatric patients with no history of seizures. Acta Neuropathol Commun. 2020;8:54 pubmed publisher
|
| Selvadurai H, Luis E, Desai K, Lan X, Vladoiu M, Whitley O, et al. Medulloblastoma Arises from the Persistence of a Rare and Transient Sox2+ Granule Neuron Precursor. Cell Rep. 2020;31:107511 pubmed publisher
|
| Mirjalili Mohanna S, Hickmott J, Lam S, Chiu N, Lengyell T, Tam B, et al. Germline CRISPR/Cas9-Mediated Gene Editing Prevents Vision Loss in a Novel Mouse Model of Aniridia. Mol Ther Methods Clin Dev. 2020;17:478-490 pubmed publisher
|
| Popovitchenko T, Park Y, Page N, Luo X, Krsnik Z, Liu Y, et al. Translational derepression of Elavl4 isoforms at their alternative 5' UTRs determines neuronal development. Nat Commun. 2020;11:1674 pubmed publisher
|
| Shao W, Yang J, He M, Yu X, Lee C, Yang Z, et al. Centrosome anchoring regulates progenitor properties and cortical formation. Nature. 2020;580:106-112 pubmed publisher
|
| Plaza Reyes A, Petrus Reurer S, Padrell Sánchez S, Kumar P, Douagi I, Bartuma H, et al. Identification of cell surface markers and establishment of monolayer differentiation to retinal pigment epithelial cells. Nat Commun. 2020;11:1609 pubmed publisher
|
| Fregeac J, Moriceau S, Poli A, Nguyen L, Oury F, Colleaux L. Loss of the neurodevelopmental disease-associated gene miR-146a impairs neural progenitor differentiation and causes learning and memory deficits. Mol Autism. 2020;11:22 pubmed publisher
|
| Gao M, Lei X, Han F, He K, Jin S, Zhang Y, et al. Patient-Specific Retinal Organoids Recapitulate Disease Features of Late-Onset Retinitis Pigmentosa. Front Cell Dev Biol. 2020;8:128 pubmed publisher
|
| Slot E, de Klein A, Rottier R. Generation of three iPSC lines from two patients with heterozygous FOXF1 mutations associated to Alveolar Capillary Dysplasia with Misalignment of the Pulmonary Veins. Stem Cell Res. 2020;44:101745 pubmed publisher
|
| Kitajima R, Nakai R, Imamura T, Kameda T, Kozuka D, Hirai H, et al. Modeling of early neural development in vitro by direct neurosphere formation culture of chimpanzee induced pluripotent stem cells. Stem Cell Res. 2020;44:101749 pubmed publisher
|
| Matsumura K, Seiriki K, Okada S, Nagase M, Ayabe S, Yamada I, et al. Pathogenic POGZ mutation causes impaired cortical development and reversible autism-like phenotypes. Nat Commun. 2020;11:859 pubmed publisher
|
| Ao Z, Cai H, Havert D, Wu Z, Gong Z, Beggs J, et al. One-Stop Microfluidic Assembly of Human Brain Organoids To Model Prenatal Cannabis Exposure. Anal Chem. 2020;92:4630-4638 pubmed publisher
|
| Chui A, Zhang Q, Dai Q, Shi S. Oxidative stress regulates progenitor behavior and cortical neurogenesis. Development. 2020;147: pubmed publisher
|
| Kafarnik C, McClellan A, Dziasko M, Daniels J, Guest D. Canine Corneal Stromal Cells Have Multipotent Mesenchymal Stromal Cell Properties In Vitro. Stem Cells Dev. 2020;29:425-439 pubmed publisher
|
| Bosze B, Moon M, Kageyama R, Brown N. Simultaneous Requirements for Hes1 in Retinal Neurogenesis and Optic Cup-Stalk Boundary Maintenance. J Neurosci. 2020;40:1501-1513 pubmed publisher
|
| Laan L, Klar J, Sobol M, Hoeber J, Shahsavani M, Kele M, et al. DNA methylation changes in Down syndrome derived neural iPSCs uncover co-dysregulation of ZNF and HOX3 families of transcription factors. Clin Epigenetics. 2020;12:9 pubmed publisher
|
| Tomita H, Cornejo F, Aranda Pino B, Woodard C, Rioseco C, Neel B, et al. The Protein Tyrosine Phosphatase Receptor Delta Regulates Developmental Neurogenesis. Cell Rep. 2020;30:215-228.e5 pubmed publisher
|
| Shafa M, Walsh T, Panchalingam K, Richardson T, Menendez L, Tian X, et al. Long-Term Stability and Differentiation Potential of Cryopreserved cGMP-Compliant Human Induced Pluripotent Stem Cells. Int J Mol Sci. 2019;21: pubmed publisher
|
| Pandey P, Tomney A, Woon M, Uth N, Shafighi F, Ngabo I, et al. End-to-End Platform for Human Pluripotent Stem Cell Manufacturing. Int J Mol Sci. 2019;21: pubmed publisher
|
| Panagiotakos G, Haveles C, Arjun A, Petrova R, Rana A, Portmann T, et al. Aberrant calcium channel splicing drives defects in cortical differentiation in Timothy syndrome. elife. 2019;8: pubmed publisher
|
| Bendriem R, Singh S, Aleem A, Antonetti D, Ross M. Tight junction protein occludin regulates progenitor Self-Renewal and survival in developing cortex. elife. 2019;8: pubmed publisher
|
| Craenen K, Verslegers M, Craeghs L, Quintens R, Janssen A, Coolkens A, et al. Abnormal retinal pigment epithelium melanogenesis as a major determinant for radiation-induced congenital eye defects. Reprod Toxicol. 2020;91:59-73 pubmed publisher
|
| Ramme A, Faust D, Koenig L, Marx U. Generation of four integration-free iPSC lines from related human donors. Stem Cell Res. 2019;41:101615 pubmed publisher
|
| Saito K, Okamoto M, Watanabe Y, Noguchi N, Nagasaka A, Nishina Y, et al. Dorsal-to-Ventral Cortical Expansion Is Physically Primed by Ventral Streaming of Early Embryonic Preplate Neurons. Cell Rep. 2019;29:1555-1567.e5 pubmed publisher
|
| Wörsdörfer P, Dalda N, Kern A, Kruger S, Wagner N, Kwok C, et al. Generation of complex human organoid models including vascular networks by incorporation of mesodermal progenitor cells. Sci Rep. 2019;9:15663 pubmed publisher
|
| Komabayashi Suzuki M, Yamanishi E, Watanabe C, Okamura M, Tabata H, Iwai R, et al. Spatiotemporally Dependent Vascularization Is Differently Utilized among Neural Progenitor Subtypes during Neocortical Development. Cell Rep. 2019;29:1113-1129.e5 pubmed publisher
|
| Singer R, Arnés L, Cui Y, Wang J, Gao Y, Guney M, et al. The Long Noncoding RNA Paupar Modulates PAX6 Regulatory Activities to Promote Alpha Cell Development and Function. Cell Metab. 2019;30:1091-1106.e8 pubmed publisher
|
| Mao X, An Q, Xi H, Yang X, Zhang X, Yuan S, et al. Single-Cell RNA Sequencing of hESC-Derived 3D Retinal Organoids Reveals Novel Genes Regulating RPC Commitment in Early Human Retinogenesis. Stem Cell Reports. 2019;13:747-760 pubmed publisher
|
| Postel M, Karam A, Pezeron G, Schneider Maunoury S, Clement F. A multiscale mathematical model of cell dynamics during neurogenesis in the mouse cerebral cortex. BMC Bioinformatics. 2019;20:470 pubmed publisher
|
| Peter C, Saito A, Hasegawa Y, Tanaka Y, Nagpal M, Perez G, et al. In vivo epigenetic editing of Sema6a promoter reverses transcallosal dysconnectivity caused by C11orf46/Arl14ep risk gene. Nat Commun. 2019;10:4112 pubmed publisher
|
| S nchez Guardado L, Lois C. Lineage does not regulate the sensory synaptic input of projection neurons in the mouse olfactory bulb. elife. 2019;8: pubmed publisher
|
| Uzquiano A, Cifuentes Diaz C, Jabali A, Romero D, Houllier A, Dingli F, et al. Mutations in the Heterotopia Gene Eml1/EML1 Severely Disrupt the Formation of Primary Cilia. Cell Rep. 2019;28:1596-1611.e10 pubmed publisher
|
| Gao F, Elliott N, Ho J, Sharp A, Shokhirev M, Hargreaves D. Heterozygous Mutations in SMARCA2 Reprogram the Enhancer Landscape by Global Retargeting of SMARCA4. Mol Cell. 2019;75:891-904.e7 pubmed publisher
|
| Bonnefont J, Tiberi L, van den Ameele J, Potier D, Gaber Z, Lin X, et al. Cortical Neurogenesis Requires Bcl6-Mediated Transcriptional Repression of Multiple Self-Renewal-Promoting Extrinsic Pathways. Neuron. 2019;103:1096-1108.e4 pubmed publisher
|
| Jin J, Ravindran P, Di Meo D, Püschel A. Igf1R/InsR function is required for axon extension and corpus callosum formation. PLoS ONE. 2019;14:e0219362 pubmed publisher
|
| Lee E, Kim N, Park J, Kang K, Kim W, Sim N, et al. Global Analysis of Intercellular Homeodomain Protein Transfer. Cell Rep. 2019;28:712-722.e3 pubmed publisher
|
| Li L, Ruan X, Wen C, Chen P, Liu W, Zhu L, et al. The COMPASS Family Protein ASH2L Mediates Corticogenesis via Transcriptional Regulation of Wnt Signaling. Cell Rep. 2019;28:698-711.e5 pubmed publisher
|
| Liu Z, Osipovitch M, Benraiss A, Huynh N, Foti R, Bates J, et al. Dysregulated Glial Differentiation in Schizophrenia May Be Relieved by Suppression of SMAD4- and REST-Dependent Signaling. Cell Rep. 2019;27:3832-3843.e6 pubmed publisher
|
| Kawaue T, Shitamukai A, Nagasaka A, Tsunekawa Y, Shinoda T, Saito K, et al. Lzts1 controls both neuronal delamination and outer radial glial-like cell generation during mammalian cerebral development. Nat Commun. 2019;10:2780 pubmed publisher
|
| Docampo Seara A, Lanoizelet M, Lagadec R, Mazan S, Candal E, Rodriguez M. Mitral cell development in the olfactory bulb of sharks: evidences of a conserved pattern of glutamatergic neurogenesis. Brain Struct Funct. 2019;: pubmed publisher
|
| Moore D, Meays B, Madduri L, Shahjin F, Chand S, Niu M, et al. Downregulation of an Evolutionary Young miR-1290 in an iPSC-Derived Neural Stem Cell Model of Autism Spectrum Disorder. Stem Cells Int. 2019;2019:8710180 pubmed publisher
|
| Velasco S, Kedaigle A, Simmons S, Nash A, Rocha M, Quadrato G, et al. Individual brain organoids reproducibly form cell diversity of the human cerebral cortex. Nature. 2019;: pubmed publisher
|
| Alexander J, Guan J, Li B, Maliskova L, Song M, Shen Y, et al. Live-cell imaging reveals enhancer-dependent Sox2 transcription in the absence of enhancer proximity. elife. 2019;8: pubmed publisher
|
| Wang H, Xiao Z, Zheng J, Wu J, Hu X, Yang X, et al. ZEB1 Represses Neural Differentiation and Cooperates with CTBP2 to Dynamically Regulate Cell Migration during Neocortex Development. Cell Rep. 2019;27:2335-2353.e6 pubmed publisher
|
| Zurkirchen L, Varum S, Giger S, Klug A, Häusel J, Bossart R, et al. Yin Yang 1 sustains biosynthetic demands during brain development in a stage-specific manner. Nat Commun. 2019;10:2192 pubmed publisher
|
| Lindsay C, Roth J, LeSavage B, Heilshorn S. Bioprinting of stem cell expansion lattices. Acta Biomater. 2019;: pubmed publisher
|
| Roy A, Murphy R, Deng M, MacDonald J, Bammler T, Aldinger K, et al. PI3K-Yap activity drives cortical gyrification and hydrocephalus in mice. elife. 2019;8: pubmed publisher
|
| Wang S, Min Z, Ji Q, Geng L, Su Y, Liu Z, et al. Rescue of premature aging defects in Cockayne syndrome stem cells by CRISPR/Cas9-mediated gene correction. Protein Cell. 2019;: pubmed publisher
|
| Langer L, Ward J, Archer T. Tumor suppressor SMARCB1 suppresses super-enhancers to govern hESC lineage determination. elife. 2019;8: pubmed publisher
|
| Wilson C, Spaeth J, Karp J, Stocks B, Hoopes E, Stein R, et al. B lymphocytes protect islet β cells in diabetes prone NOD mice treated with imatinib. JCI Insight. 2019;5: pubmed publisher
|
| Bashford A, Subramanian V. Mice with a conditional deletion of Talpid3 (KIAA0586) - a model for Joubert syndrome. J Pathol. 2019;248:396-408 pubmed publisher
|
| Ren X, Hu B, Song M, Ding Z, Dang Y, Liu Z, et al. Maintenance of Nucleolar Homeostasis by CBX4 Alleviates Senescence and Osteoarthritis. Cell Rep. 2019;26:3643-3656.e7 pubmed publisher
|
| Alzu bi A, Clowry G. Expression of ventral telencephalon transcription factors ASCL1 and DLX2 in the early fetal human cerebral cortex. J Anat. 2019;235:555-568 pubmed publisher
|
| Ooi J, Langley S, Xu X, Utami K, Sim B, Huang Y, et al. Unbiased Profiling of Isogenic Huntington Disease hPSC-Derived CNS and Peripheral Cells Reveals Strong Cell-Type Specificity of CAG Length Effects. Cell Rep. 2019;26:2494-2508.e7 pubmed publisher
|
| Zhang X, Liu Z, Liu X, Wang S, Zhang Y, He X, et al. Telomere-dependent and telomere-independent roles of RAP1 in regulating human stem cell homeostasis. Protein Cell. 2019;: pubmed publisher
|
| Pollen A, Bhaduri A, Andrews M, Nowakowski T, Meyerson O, Mostajo Radji M, et al. Establishing Cerebral Organoids as Models of Human-Specific Brain Evolution. Cell. 2019;176:743-756.e17 pubmed publisher
|
| Klein T, Klug K, Henkel L, Kwok C, Edenhofer F, Klopocki E, et al. Generation of two induced pluripotent stem cell lines from skin fibroblasts of sisters carrying a c.1094C>A variation in the SCN10A gene potentially associated with small fiber neuropathy. Stem Cell Res. 2019;35:101396 pubmed publisher
|
| Ward J, Stoyas C, Switonski P, Ichou F, Fan W, Collins B, et al. Metabolic and Organelle Morphology Defects in Mice and Human Patients Define Spinocerebellar Ataxia Type 7 as a Mitochondrial Disease. Cell Rep. 2019;26:1189-1202.e6 pubmed publisher
|
| Chang C, Zanini M, Shirvani H, Cheng J, Yu H, Feng C, et al. Atoh1 Controls Primary Cilia Formation to Allow for SHH-Triggered Granule Neuron Progenitor Proliferation. Dev Cell. 2019;48:184-199.e5 pubmed publisher
|
| Cheng S, Liu T, Hu Y, Xia Y, Hou J, Huang C, et al. Conditional Inactivation of Pen-2 in the Developing Neocortex Leads to Rapid Switch of Apical Progenitors to Basal Progenitors. J Neurosci. 2019;39:2195-2207 pubmed publisher
|
| Wu Z, Makihara S, Yam P, Teo S, Renier N, Balekoglu N, et al. Long-Range Guidance of Spinal Commissural Axons by Netrin1 and Sonic Hedgehog from Midline Floor Plate Cells. Neuron. 2019;101:635-647.e4 pubmed publisher
|
| Lim Y, Cho I, Shi X, Grinspan J, Cho G, Golden J. Arx Expression Suppresses Ventralization of the Developing Dorsal Forebrain. Sci Rep. 2019;9:226 pubmed publisher
|
| Robson J, Remke M, Kool M, Julian E, Korshunov A, Pfister S, et al. Identification of CD24 as a marker of Patched1 deleted medulloblastoma-initiating neural progenitor cells. PLoS ONE. 2019;14:e0210665 pubmed publisher
|
| Chen Y, Tristan C, Mallanna S, Ormanoglu P, Titus S, Simeonov A, et al. Chemically Defined Neural Conversion of Human Pluripotent Stem Cells. Methods Mol Biol. 2019;1919:59-72 pubmed publisher
|
| Ding W, Wu Q, Sun L, Pan N, Wang X. Cenpj Regulates Cilia Disassembly and Neurogenesis in the Developing Mouse Cortex. J Neurosci. 2019;39:1994-2010 pubmed publisher
|
| Shu P, Wu C, Liu W, Ruan X, Liu C, Hou L, et al. The spatiotemporal expression pattern of microRNAs in the developing mouse nervous system. J Biol Chem. 2019;294:3444-3453 pubmed publisher
|
| Xu D, Yao M, Wang Y, Yuan L, Hoeck J, Yu J, et al. MEKK3 coordinates with FBW7 to regulate WDR62 stability and neurogenesis. PLoS Biol. 2018;16:e2006613 pubmed publisher
|
| Yin W, Satkunendran T, Mo R, Morrissy S, Zhang X, Huang E, et al. Dual Regulatory Functions of SUFU and Targetome of GLI2 in SHH Subgroup Medulloblastoma. Dev Cell. 2019;48:167-183.e5 pubmed publisher
|
| Lavado A, Park J, Pare J, Finkelstein D, Pan H, Xu B, et al. The Hippo Pathway Prevents YAP/TAZ-Driven Hypertranscription and Controls Neural Progenitor Number. Dev Cell. 2018;47:576-591.e8 pubmed publisher
|
| Diacou R, Zhao Y, Zheng D, Cvekl A, Liu W. Six3 and Six6 Are Jointly Required for the Maintenance of Multipotent Retinal Progenitors through Both Positive and Negative Regulation. Cell Rep. 2018;25:2510-2523.e4 pubmed publisher
|
| Nowakowski T, Rani N, Golkaram M, Zhou H, Alvarado B, Huch K, et al. Regulation of cell-type-specific transcriptomes by microRNA networks during human brain development. Nat Neurosci. 2018;21:1784-1792 pubmed publisher
|
| Tripathy R, Leca I, van Dijk T, Weiss J, van Bon B, Sergaki M, et al. Mutations in MAST1 Cause Mega-Corpus-Callosum Syndrome with Cerebellar Hypoplasia and Cortical Malformations. Neuron. 2018;100:1354-1368.e5 pubmed publisher
|
| Shibata S, Hayashi R, Okubo T, Kudo Y, Katayama T, Ishikawa Y, et al. Selective Laminin-Directed Differentiation of Human Induced Pluripotent Stem Cells into Distinct Ocular Lineages. Cell Rep. 2018;25:1668-1679.e5 pubmed publisher
|
| Cargnin F, Kwon J, Katzman S, Chen B, Lee J, Lee S. FOXG1 Orchestrates Neocortical Organization and Cortico-Cortical Connections. Neuron. 2018;100:1083-1096.e5 pubmed publisher
|
| Klein T, Henkel L, Klug K, Kwok C, Klopocki E, Uceyler N. Generation of the human induced pluripotent stem cell line UKWNLi002-A from dermal fibroblasts of a woman with a heterozygous c.608 C>T (p.Thr203Met) mutation in exon 3 of the nerve growth factor gene potentially associated with hereditary sensory. Stem Cell Res. 2018;33:171-174 pubmed publisher
|
| Kim Y, Khoshkhoo S, Frankowski J, Zhu B, Abbasi S, Lee S, et al. Chd2 Is Necessary for Neural Circuit Development and Long-Term Memory. Neuron. 2018;100:1180-1193.e6 pubmed publisher
|
| Nazir F, Becker B, Brinkmalm A, Höglund K, Sandelius Å, Bergström P, et al. Expression and secretion of synaptic proteins during stem cell differentiation to cortical neurons. Neurochem Int. 2018;121:38-49 pubmed publisher
|
| Omer Javed A, Li Y, Muffat J, Su K, Cohen M, Lungjangwa T, et al. Microcephaly Modeling of Kinetochore Mutation Reveals a Brain-Specific Phenotype. Cell Rep. 2018;25:368-382.e5 pubmed publisher
|
| Bovio P, Franz H, Heidrich S, Rauleac T, Kilpert F, Manke T, et al. Differential Methylation of H3K79 Reveals DOT1L Target Genes and Function in the Cerebellum In Vivo. Mol Neurobiol. 2019;56:4273-4287 pubmed publisher
|
| Hickmott J, Gunawardane U, Jensen K, Korecki A, Simpson E. Epistasis between Pax6Sey and genetic background reinforces the value of defined hybrid mouse models for therapeutic trials. Gene Ther. 2018;25:524-537 pubmed publisher
|
| Ibañez Rodriguez M, Galiana M, Rasmussen J, Freites C, Noctor S, Muñoz E. Differential response of pineal microglia to surgical versus pharmacological stimuli. J Comp Neurol. 2018;526:2462-2481 pubmed publisher
|
| Zhang Y, Yang Y, Jiang M, Huang S, Zhang W, Al Alam D, et al. 3D Modeling of Esophageal Development using Human PSC-Derived Basal Progenitors Reveals a Critical Role for Notch Signaling. Cell Stem Cell. 2018;23:516-529.e5 pubmed publisher
|
| Homman Ludiye J, Kwan W, de Souza M, Bourne J. Full: Ontogenesis and development of the nonhuman primate pulvinar. J Comp Neurol. 2018;526:2870-2883 pubmed publisher
|
| Kurabayashi N, Tanaka A, Nguyen M, Sanada K. The LPA-LPA4 axis is required for establishment of bipolar morphology and radial migration of newborn cortical neurons. Development. 2018;145: pubmed publisher
|
| Han S, Dennis D, Balakrishnan A, Dixit R, Britz O, Zinyk D, et al. A non-canonical role for the proneural gene Neurog1 as a negative regulator of neocortical neurogenesis. Development. 2018;145: pubmed publisher
|
| Segarra M, Aburto M, Cop F, Llaó Cid C, Härtl R, Damm M, et al. Endothelial Dab1 signaling orchestrates neuro-glia-vessel communication in the central nervous system. Science. 2018;361: pubmed publisher
|
| Klein T, Günther K, Kwok C, Edenhofer F, Uceyler N. Generation of the human induced pluripotent stem cell line (UKWNLi001-A) from skin fibroblasts of a woman with Fabry disease carrying the X-chromosomal heterozygous c.708 G > C (W236C) missense mutation in exon 5 of the alpha-galactosidase-A gene. Stem Cell Res. 2018;31:222-226 pubmed publisher
|
| Le Dreau G, Escalona R, Fueyo R, Herrera A, Martinez J, Usieto S, et al. E proteins sharpen neurogenesis by modulating proneural bHLH transcription factors' activity in an E-box-dependent manner. elife. 2018;7: pubmed publisher
|
| Tang Y, Xiong S, Yu P, Liu F, Cheng L. Direct Conversion of Mouse Fibroblasts into Neural Stem Cells by Chemical Cocktail Requires Stepwise Activation of Growth Factors and Nup210. Cell Rep. 2018;24:1355-1362.e3 pubmed publisher
|
| Docampo Seara A, Lagadec R, Mazan S, Rodriguez M, Quintana Urzainqui I, Candal E. Study of pallial neurogenesis in shark embryos and the evolutionary origin of the subventricular zone. Brain Struct Funct. 2018;223:3593-3612 pubmed publisher
|
| Miesfeld J, Moon M, Riesenberg A, Contreras A, Kovall R, Brown N. Rbpj direct regulation of Atoh7 transcription in the embryonic mouse retina. Sci Rep. 2018;8:10195 pubmed publisher
|
| Nakano Y, Kelly M, Rehman A, Boger E, Morell R, Kelley M, et al. Defects in the Alternative Splicing-Dependent Regulation of REST Cause Deafness. Cell. 2018;174:536-548.e21 pubmed publisher
|
| Watanabe Y, Kawaue T, Miyata T. Differentiating cells mechanically limit the interkinetic nuclear migration of progenitor cells to secure apical cytogenesis. Development. 2018;145: pubmed publisher
|
| Dominguez Gonzalez B, Billion K, Rous S, Pavie B, Lange C, Goodchild R. Excess LINC complexes impair brain morphogenesis in a mouse model of recessive TOR1A disease. Hum Mol Genet. 2018;27:2154-2170 pubmed publisher
|
| Luisier R, Tyzack G, Hall C, Mitchell J, Devine H, Taha D, et al. Intron retention and nuclear loss of SFPQ are molecular hallmarks of ALS. Nat Commun. 2018;9:2010 pubmed publisher
|
| Baizabal J, Mistry M, Garcia M, Gómez N, Olukoya O, Tran D, et al. The Epigenetic State of PRDM16-Regulated Enhancers in Radial Glia Controls Cortical Neuron Position. Neuron. 2018;98:945-962.e8 pubmed publisher
|
| Karzbrun E, Kshirsagar A, Cohen S, Hanna J, Reiner O. Human Brain Organoids on a Chip Reveal the Physics of Folding. Nat Phys. 2018;14:515-522 pubmed publisher
|
| Chau K, Shannon M, Fame R, Fonseca E, Mullan H, Johnson M, et al. Downregulation of ribosome biogenesis during early forebrain development. elife. 2018;7: pubmed publisher
|
| Dhumale P, Menon S, Chiang J, Püschel A. The loss of the kinases SadA and SadB results in early neuronal apoptosis and a reduced number of progenitors. PLoS ONE. 2018;13:e0196698 pubmed publisher
|
| Shafa M, Yang F, Fellner T, Rao M, Baghbaderani B. Human-Induced Pluripotent Stem Cells Manufactured Using a Current Good Manufacturing Practice-Compliant Process Differentiate Into Clinically Relevant Cells From Three Germ Layers. Front Med (Lausanne). 2018;5:69 pubmed publisher
|
| Ing Esteves S, Kostadinov D, Marocha J, Sing A, Joseph K, Laboulaye M, et al. Combinatorial Effects of Alpha- and Gamma-Protocadherins on Neuronal Survival and Dendritic Self-Avoidance. J Neurosci. 2018;38:2713-2729 pubmed publisher
|
| Janssens S, Schotsaert M, Karnik R, Balasubramaniam V, Dejosez M, Meissner A, et al. Zika Virus Alters DNA Methylation of Neural Genes in an Organoid Model of the Developing Human Brain. mSystems. 2018;3: pubmed publisher
|
| Tu J, Huo Z, Liu M, Wang D, Xu A, Zhou R, et al. Generation of human embryonic stem cell line with heterozygous RB1 deletion by CRIPSR/Cas9 nickase. Stem Cell Res. 2018;28:29-32 pubmed publisher
|
| Zahr S, Yang G, Kazan H, Borrett M, Yuzwa S, Voronova A, et al. A Translational Repression Complex in Developing Mammalian Neural Stem Cells that Regulates Neuronal Specification. Neuron. 2018;97:520-537.e6 pubmed publisher
|
| Parween S, Varghese D, Ardah M, Prabakaran A, Mensah Brown E, Emerald B, et al. Higher O-GlcNAc Levels Are Associated with Defects in Progenitor Proliferation and Premature Neuronal Differentiation during in-Vitro Human Embryonic Cortical Neurogenesis. Front Cell Neurosci. 2017;11:415 pubmed publisher
|
| Goodson N, Nahreini J, Randazzo G, Uruena A, Johnson J, Brzezinski J. Prdm13 is required for Ebf3+ amacrine cell formation in the retina. Dev Biol. 2018;434:149-163 pubmed publisher
|
| Wu X, Dao Thi V, Huang Y, Billerbeck E, Saha D, Hoffmann H, et al. Intrinsic Immunity Shapes Viral Resistance of Stem Cells. Cell. 2018;172:423-438.e25 pubmed publisher
|
| Hoshino A, Ratnapriya R, Brooks M, Chaitankar V, Wilken M, Zhang C, et al. Molecular Anatomy of the Developing Human Retina. Dev Cell. 2017;43:763-779.e4 pubmed publisher
|
| Scior A, Buntru A, Arnsburg K, Ast A, Iburg M, Juenemann K, et al. Complete suppression of Htt fibrilization and disaggregation of Htt fibrils by a trimeric chaperone complex. EMBO J. 2018;37:282-299 pubmed publisher
|
| Todd L, Suarez L, Quinn C, Fischer A. Retinoic Acid-Signaling Regulates the Proliferative and Neurogenic Capacity of Müller Glia-Derived Progenitor Cells in the Avian Retina. Stem Cells. 2018;36:392-405 pubmed publisher
|
| Broix L, Asselin L, Silva C, Ivanova E, Tilly P, Gilet J, et al. Ciliogenesis and cell cycle alterations contribute to KIF2A-related malformations of cortical development. Hum Mol Genet. 2018;27:224-238 pubmed publisher
|
| Liu J, Liu W, Yang L, Wu Q, Zhang H, Fang A, et al. The Primate-Specific Gene TMEM14B Marks Outer Radial Glia Cells and Promotes Cortical Expansion and Folding. Cell Stem Cell. 2017;21:635-649.e8 pubmed publisher
|
| Ramzy A, Mojibian M, Kieffer T. Insulin-Deficient Mouse β-Cells Do Not Fully Maturebut Can Be Remedied Through Insulin Replacementby Islet Transplantation. Endocrinology. 2018;159:83-102 pubmed publisher
|
| Remez L, Onishi A, Menuchin Lasowski Y, Biran A, Blackshaw S, Wahlin K, et al. Pax6 is essential for the generation of late-born retinal neurons and for inhibition of photoreceptor-fate during late stages of retinogenesis. Dev Biol. 2017;432:140-150 pubmed publisher
|
| Palencia Campos A, Ullah A, Nevado J, Yildirim R, Unal E, Ciorraga M, et al. GLI1 inactivation is associated with developmental phenotypes overlapping with Ellis-van Creveld syndrome. Hum Mol Genet. 2017;26:4556-4571 pubmed publisher
|
| Cliff T, Wu T, Boward B, Yin A, Yin H, Glushka J, et al. MYC Controls Human Pluripotent Stem Cell Fate Decisions through Regulation of Metabolic Flux. Cell Stem Cell. 2017;21:502-516.e9 pubmed publisher
|
| Mills T, Eliseeva T, Bersie S, Randazzo G, Nahreini J, Park K, et al. Combinatorial regulation of a Blimp1 (Prdm1) enhancer in the mouse retina. PLoS ONE. 2017;12:e0176905 pubmed publisher
|
| Forrest M, Zhang H, Moy W, McGowan H, Leites C, Dionisio L, et al. Open Chromatin Profiling in hiPSC-Derived Neurons Prioritizes Functional Noncoding Psychiatric Risk Variants and Highlights Neurodevelopmental Loci. Cell Stem Cell. 2017;21:305-318.e8 pubmed publisher
|
| Zhu Y, Wang L, Yu H, Yin F, Wang Y, Liu H, et al. In situ generation of human brain organoids on a micropillar array. Lab Chip. 2017;17:2941-2950 pubmed publisher
|
| Hu X, Chen G, Zhang S, Zheng J, Wu J, Bai Q, et al. Persistent Expression of VCAM1 in Radial Glial Cells Is Required for the Embryonic Origin of Postnatal Neural Stem Cells. Neuron. 2017;95:309-325.e6 pubmed publisher
|
| Todd L, Palazzo I, Squires N, Mendonca N, Fischer A. BMP- and TGF?-signaling regulate the formation of Müller glia-derived progenitor cells in the avian retina. Glia. 2017;65:1640-1655 pubmed publisher
|
| Sun D, Zhou X, Yu H, He X, Guo W, Xiong W, et al. Regulation of neural stem cell proliferation and differentiation by Kinesin family member 2a. PLoS ONE. 2017;12:e0179047 pubmed publisher
|
| Wang Q, Yue W, Jiang Z, Xue T, Kang S, Bergles D, et al. Synergistic Signaling by Light and Acetylcholine in Mouse Iris Sphincter Muscle. Curr Biol. 2017;27:1791-1800.e5 pubmed publisher
|
| Andres L, Blong I, Evans A, Rumachik N, Yamaguchi T, Pham N, et al. Chemical Modulation of Protein O-GlcNAcylation via OGT Inhibition Promotes Human Neural Cell Differentiation. ACS Chem Biol. 2017;12:2030-2039 pubmed publisher
|
| Sano N, Shimogawa T, Sakaguchi H, Ioroi Y, Miyawaki Y, Morizane A, et al. Enhanced Axonal Extension of Subcortical Projection Neurons Isolated from Murine Embryonic Cortex using Neuropilin-1. Front Cell Neurosci. 2017;11:123 pubmed publisher
|
| del Toro D, Ruff T, Cederfjäll E, Villalba A, Seyit Bremer G, Borrell V, et al. Regulation of Cerebral Cortex Folding by Controlling Neuronal Migration via FLRT Adhesion Molecules. Cell. 2017;169:621-635.e16 pubmed publisher
|
| Beattie R, Postiglione M, Burnett L, Laukoter S, Streicher C, Pauler F, et al. Mosaic Analysis with Double Markers Reveals Distinct Sequential Functions of Lgl1 in Neural Stem Cells. Neuron. 2017;94:517-533.e3 pubmed publisher
|
| Lu H, Tan Q, Rousseaux M, Wang W, Kim J, Richman R, et al. Disruption of the ATXN1-CIC complex causes a spectrum of neurobehavioral phenotypes in mice and humans. Nat Genet. 2017;49:527-536 pubmed publisher
|
| Hayashi R, Ishikawa Y, Katori R, Sasamoto Y, Taniwaki Y, Takayanagi H, et al. Coordinated generation of multiple ocular-like cell lineages and fabrication of functional corneal epithelial cell sheets from human iPS cells. Nat Protoc. 2017;12:683-696 pubmed publisher
|
| Miyashita H, Niwano H, Yoshida S, Hatou S, Inagaki E, Tsubota K, et al. Long-term homeostasis and wound healing in an in vitro epithelial stem cell niche model. Sci Rep. 2017;7:43557 pubmed publisher
|
| Mochizuki T, Luo Y, Tsai H, Hagiwara A, Masai I. Cell division and cadherin-mediated adhesion regulate lens epithelial cell movement in zebrafish. Development. 2017;144:708-719 pubmed publisher
|
| Subramanian L, Bershteyn M, Paredes M, Kriegstein A. Dynamic behaviour of human neuroepithelial cells in the developing forebrain. Nat Commun. 2017;8:14167 pubmed publisher
|
| Ren R, Deng L, Xue Y, Suzuki K, Zhang W, Yu Y, et al. Visualization of aging-associated chromatin alterations with an engineered TALE system. Cell Res. 2017;27:483-504 pubmed publisher
|
| Boland M, Nazor K, Tran H, Szucs A, Lynch C, Paredes R, et al. Molecular analyses of neurogenic defects in a human pluripotent stem cell model of fragile X syndrome. Brain. 2017;140:582-598 pubmed publisher
|
| Gabriel E, Ramani A, Karow U, Gottardo M, Natarajan K, Gooi L, et al. Recent Zika Virus Isolates Induce Premature Differentiation of Neural Progenitors in Human Brain Organoids. Cell Stem Cell. 2017;20:397-406.e5 pubmed publisher
|
| Bershteyn M, Nowakowski T, Pollen A, Di Lullo E, Nene A, Wynshaw Boris A, et al. Human iPSC-Derived Cerebral Organoids Model Cellular Features of Lissencephaly and Reveal Prolonged Mitosis of Outer Radial Glia. Cell Stem Cell. 2017;20:435-449.e4 pubmed publisher
|
| Lardelli R, Schaffer A, Eggens V, Zaki M, Grainger S, Sathe S, et al. Biallelic mutations in the 3' exonuclease TOE1 cause pontocerebellar hypoplasia and uncover a role in snRNA processing. Nat Genet. 2017;49:457-464 pubmed publisher
|
| Breuss M, Nguyen T, Srivatsan A, Leca I, Tian G, Fritz T, et al. Uner Tan syndrome caused by a homozygous TUBB2B mutation affecting microtubule stability. Hum Mol Genet. 2017;26:258-269 pubmed publisher
|
| Retallack H, Di Lullo E, Arias C, Knopp K, Laurie M, Sandoval Espinosa C, et al. Zika virus cell tropism in the developing human brain and inhibition by azithromycin. Proc Natl Acad Sci U S A. 2016;113:14408-14413 pubmed
|
| Lajko M, Cardona H, Taylor J, Shah R, Farrow K, Fawzi A. Hyperoxia-Induced Proliferative Retinopathy: Early Interruption of Retinal Vascular Development with Severe and Irreversible Neurovascular Disruption. PLoS ONE. 2016;11:e0166886 pubmed publisher
|
| Ibañez Rodriguez M, Noctor S, Muñoz E. Cellular Basis of Pineal Gland Development: Emerging Role of Microglia as Phenotype Regulator. PLoS ONE. 2016;11:e0167063 pubmed publisher
|
| Damiani D, Goffinet A, ALBERTS A, Tissir F. Lack of Diaph3 relaxes the spindle checkpoint causing the loss of neural progenitors. Nat Commun. 2016;7:13509 pubmed publisher
|
| Tao C, Zhang X. Retinal Proteoglycans Act as Cellular Receptors for Basement Membrane Assembly to Control Astrocyte Migration and Angiogenesis. Cell Rep. 2016;17:1832-1844 pubmed publisher
|
| Zhu L, Gómez Durán A, Saretzki G, Jin S, Tilgner K, Melguizo Sanchís D, et al. The mitochondrial protein CHCHD2 primes the differentiation potential of human induced pluripotent stem cells to neuroectodermal lineages. J Cell Biol. 2016;215:187-202 pubmed
|
| Pei S, Liu L, Zhong Z, Wang H, Lin S, Shang J. Risk of prenatal depression and stress treatment: alteration on serotonin system of offspring through exposure to Fluoxetine. Sci Rep. 2016;6:33822 pubmed publisher
|
| Broix L, Jagline H, Ivanova E, Schmucker S, Drouot N, Clayton Smith J, et al. Mutations in the HECT domain of NEDD4L lead to AKT-mTOR pathway deregulation and cause periventricular nodular heterotopia. Nat Genet. 2016;48:1349-1358 pubmed publisher
|
| Simonin Y, Loustalot F, Desmetz C, Foulongne V, Constant O, Fournier Wirth C, et al. Zika Virus Strains Potentially Display Different Infectious Profiles in Human Neural Cells. EBioMedicine. 2016;12:161-169 pubmed publisher
|
| Tachibana N, Cantrup R, Dixit R, Touahri Y, Kaushik G, Zinyk D, et al. Pten Regulates Retinal Amacrine Cell Number by Modulating Akt, Tgf?, and Erk Signaling. J Neurosci. 2016;36:9454-71 pubmed publisher
|
| Yeung J, Ha T, Swanson D, Goldowitz D. A Novel and Multivalent Role of Pax6 in Cerebellar Development. J Neurosci. 2016;36:9057-69 pubmed publisher
|
| Hickmott J, Chen C, Arenillas D, Korecki A, Lam S, Molday L, et al. PAX6 MiniPromoters drive restricted expression from rAAV in the adult mouse retina. Mol Ther Methods Clin Dev. 2016;3:16051 pubmed publisher
|
| Wiley L, Burnight E, DeLuca A, Anfinson K, Cranston C, Kaalberg E, et al. cGMP production of patient-specific iPSCs and photoreceptor precursor cells to treat retinal degenerative blindness. Sci Rep. 2016;6:30742 pubmed publisher
|
| Bonney S, Harrison Uy S, Mishra S, MacPherson A, Choe Y, Li D, et al. Diverse Functions of Retinoic Acid in Brain Vascular Development. J Neurosci. 2016;36:7786-801 pubmed publisher
|
| Abdullah A, Zhang H, Nie Y, Tang W, Sun T. CDK7 and miR-210 Co-regulate Cell-Cycle Progression of Neural Progenitors in the Developing Neocortex. Stem Cell Reports. 2016;7:69-79 pubmed publisher
|
| Toda T, Shinmyo Y, Dinh Duong T, Masuda K, Kawasaki H. An essential role of SVZ progenitors in cortical folding in gyrencephalic mammals. Sci Rep. 2016;6:29578 pubmed publisher
|
| Tian E, Sun G, Sun G, Chao J, Ye P, Warden C, et al. Small-Molecule-Based Lineage Reprogramming Creates Functional Astrocytes. Cell Rep. 2016;16:781-92 pubmed publisher
|
| Moura D, Fernández I, MarÃn Royo G, López Sánchez I, MartÃn Doncel E, Vega F, et al. Oncogenic Sox2 regulates and cooperates with VRK1 in cell cycle progression and differentiation. Sci Rep. 2016;6:28532 pubmed publisher
|
| Wu J, Hussaini S, Bastille I, Rodriguez G, Mrejeru A, Rilett K, et al. Neuronal activity enhances tau propagation and tau pathology in vivo. Nat Neurosci. 2016;19:1085-92 pubmed publisher
|
| Plaisted W, Zavala A, Hingco E, Tran H, Coleman R, Lane T, et al. Remyelination Is Correlated with Regulatory T Cell Induction Following Human Embryoid Body-Derived Neural Precursor Cell Transplantation in a Viral Model of Multiple Sclerosis. PLoS ONE. 2016;11:e0157620 pubmed publisher
|
| Cugola F, Fernandes I, Russo F, Freitas B, Dias J, Guimarães K, et al. The Brazilian Zika virus strain causes birth defects in experimental models. Nature. 2016;534:267-71 pubmed publisher
|
| He S, Limi S, McGreal R, Xie Q, Brennan L, Kantorow W, et al. Chromatin remodeling enzyme Snf2h regulates embryonic lens differentiation and denucleation. Development. 2016;143:1937-47 pubmed publisher
|
| Wang L, Hou S, Han Y. Hedgehog signaling promotes basal progenitor expansion and the growth and folding of the neocortex. Nat Neurosci. 2016;19:888-96 pubmed publisher
|
| Garreta E, de Oñate L, Fernández Santos M, Oria R, Tarantino C, Climent A, et al. Myocardial commitment from human pluripotent stem cells: Rapid production of human heart grafts. Biomaterials. 2016;98:64-78 pubmed publisher
|
| Feng J, Xian Q, Guan T, Hu J, Wang M, Huang Y, et al. Celsr3 and Fzd3 Organize a Pioneer Neuron Scaffold to Steer Growing Thalamocortical Axons. Cereb Cortex. 2016;26:3323-34 pubmed publisher
|
| Takeo Y, Kurabayashi N, Nguyen M, Sanada K. The G protein-coupled receptor GPR157 regulates neuronal differentiation of radial glial progenitors through the Gq-IP3 pathway. Sci Rep. 2016;6:25180 pubmed publisher
|
| Paquet D, Kwart D, Chen A, Sproul A, Jacob S, Teo S, et al. Efficient introduction of specific homozygous and heterozygous mutations using CRISPR/Cas9. Nature. 2016;533:125-9 pubmed publisher
|
| Okamoto M, Miyata T, Konno D, Ueda H, Kasukawa T, Hashimoto M, et al. Cell-cycle-independent transitions in temporal identity of mammalian neural progenitor cells. Nat Commun. 2016;7:11349 pubmed publisher
|
| Xu J, Fan J, Wang X, Eacker S, Kam T, Chen L, et al. Cultured networks of excitatory projection neurons and inhibitory interneurons for studying human cortical neurotoxicity. Sci Transl Med. 2016;8:333ra48 pubmed publisher
|
| Otani T, Marchetto M, Gage F, Simons B, Livesey F. 2D and 3D Stem Cell Models of Primate Cortical Development Identify Species-Specific Differences in Progenitor Behavior Contributing to Brain Size. Cell Stem Cell. 2016;18:467-80 pubmed publisher
|
| Lin H, Ouyang H, Zhu J, Huang S, Liu Z, Chen S, et al. Lens regeneration using endogenous stem cells with gain of visual function. Nature. 2016;531:323-8 pubmed publisher
|
| Wang W, Jossin Y, Chai G, Lien W, Tissir F, Goffinet A. Feedback regulation of apical progenitor fate by immature neurons through Wnt7-Celsr3-Fzd3 signalling. Nat Commun. 2016;7:10936 pubmed publisher
|
| Sancho Martinez I, Nivet E, Xia Y, Hishida T, Aguirre A, Ocampo A, et al. Establishment of human iPSC-based models for the study and targeting of glioma initiating cells. Nat Commun. 2016;7:10743 pubmed publisher
|
| Taverna E, Mora Bermúdez F, Strzyz P, Florio M, Icha J, Haffner C, et al. Non-canonical features of the Golgi apparatus in bipolar epithelial neural stem cells. Sci Rep. 2016;6:21206 pubmed publisher
|
| Verheyen A, Diels A, Dijkmans J, Oyelami T, Meneghello G, Mertens L, et al. Using Human iPSC-Derived Neurons to Model TAU Aggregation. PLoS ONE. 2015;10:e0146127 pubmed publisher
|
| Ahmad Z, Rafeeq M, Collombat P, Mansouri A. Pax6 Inactivation in the Adult Pancreas Reveals Ghrelin as Endocrine Cell Maturation Marker. PLoS ONE. 2015;10:e0144597 pubmed publisher
|
| Delépine C, Meziane H, Nectoux J, Opitz M, Smith A, Ballatore C, et al. Altered microtubule dynamics and vesicular transport in mouse and human MeCP2-deficient astrocytes. Hum Mol Genet. 2016;25:146-57 pubmed publisher
|
| Conrad E, Dai C, Spaeth J, Guo M, Cyphert H, Scoville D, et al. The MAFB transcription factor impacts islet α-cell function in rodents and represents a unique signature of primate islet β-cells. Am J Physiol Endocrinol Metab. 2016;310:E91-E102 pubmed publisher
|
| Pataskar A, Jung J, Smialowski P, Noack F, Calegari F, Straub T, et al. NeuroD1 reprograms chromatin and transcription factor landscapes to induce the neuronal program. EMBO J. 2016;35:24-45 pubmed publisher
|
| Martinez Cerdeno V, Camacho J, Fox E, Miller E, Ariza J, Kienzle D, et al. Prenatal Exposure to Autism-Specific Maternal Autoantibodies Alters Proliferation of Cortical Neural Precursor Cells, Enlarges Brain, and Increases Neuronal Size in Adult Animals. Cereb Cortex. 2016;26:374-383 pubmed publisher
|
| Radonjić N, Memi F, Ortega J, Glidden N, Zhan H, Zecevic N. The Role of Sonic Hedgehog in the Specification of Human Cortical Progenitors In Vitro. Cereb Cortex. 2016;26:131-43 pubmed publisher
|
| Bando Y, Irie K, Shimomura T, Umeshima H, Kushida Y, Kengaku M, et al. Control of Spontaneous Ca2+ Transients Is Critical for Neuronal Maturation in the Developing Neocortex. Cereb Cortex. 2016;26:106-117 pubmed publisher
|