Purified anti-TMEM119 (Extracellular) | BioLegend 853302 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

Purified anti-TMEM119 (Extracellular)

catalog :

853302

quantity :

100 μg

price :

288 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

A16075D

reactivity :

human

application :

western blot, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

BioLegend product webpage

citations: 11

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry - frozen section; human; 1:200; fig 4b	Bodnar B, Zhang Y, Liu J, Lin Y, Wang P, Wei Z, et al. Novel Scalable and Simplified System to Generate Microglia-Containing Cerebral Organoids From Human Induced Pluripotent Stem Cells. Front Cell Neurosci. 2021;15:682272 pubmed publisher
	Tang Y, Chaillon A, Gianella S, Wong L, Li D, Simermeyer T, et al. Brain microglia serve as a persistent HIV reservoir despite durable antiretroviral therapy. J Clin Invest. 2023;133: pubmed publisher
	Patel T, Carnwath T, Wang X, Allen M, Lincoln S, Lewis Tuffin L, et al. Transcriptional landscape of human microglia implicates age, sex, and APOE-related immunometabolic pathway perturbations. Aging Cell. 2022;21:e13606 pubmed publisher
	Toedebusch R, Lucchesi C, Debebe E, Wittenburg L, Chen X, Toedebusch C. Microglia-Derived Olfactomedin-like 3 Promotes Pro-Tumorigenic Microglial Function and Malignant Features of Glioma Cells. Int J Mol Sci. 2021;22: pubmed publisher
	Yeini E, Ofek P, Pozzi S, Albeck N, Ben Shushan D, Tiram G, et al. P-selectin axis plays a key role in microglia immunophenotype and glioblastoma progression. Nat Commun. 2021;12:1912 pubmed publisher
	Kumar A, Kim S, Su Y, Sharma M, Kumar P, Singh S, et al. Brain cell-derived exosomes in plasma serve as neurodegeneration biomarkers in male cynomolgus monkeys self-administrating oxycodone. EBioMedicine. 2021;63:103192 pubmed publisher
	Rai M, Hammonds J, Pujato M, Mayhew C, Roskin K, Spearman P. Comparative analysis of human microglial models for studies of HIV replication and pathogenesis. Retrovirology. 2020;17:35 pubmed publisher
	Kathiriya J, Brumwell A, Jackson J, Tang X, Chapman H. Distinct Airway Epithelial Stem Cells Hide among Club Cells but Mobilize to Promote Alveolar Regeneration. Cell Stem Cell. 2020;26:346-358.e4 pubmed publisher
	Chen P, Hsu W, Chang A, Tan Z, Lan Z, Zhou A, et al. Circadian Regulator CLOCK Recruits Immune-Suppressive Microglia into the GBM Tumor Microenvironment. Cancer Discov. 2020;10:371-381 pubmed publisher
	Ruan C, Sun L, Kroshilina A, Beckers L, De Jager P, Bradshaw E, et al. A novel Tmem119-tdTomato reporter mouse model for studying microglia in the central nervous system. Brain Behav Immun. 2020;83:180-191 pubmed publisher
	Bennett F, Bennett M, Yaqoob F, Mulinyawe S, Grant G, Hayden Gephart M, et al. A Combination of Ontogeny and CNS Environment Establishes Microglial Identity. Neuron. 2018;98:1170-1183.e8 pubmed publisher

product information

Antigen :

TMEM119

Apps. Abbrev. :

FC, WB, ICC, IHC-P

Cat # :

853302

Clone :

A16075D

Item :

Purified anti-TMEM119 (Extracellular)

Isotype :

Mouse IgG2b, κ

Other Names :

Transmembrane protein 119

Size :

100 μg

Price (USD) :

288 USD

Reactivity :

Human

Clonality :

Monoclonal

Host :

Mouse

Conjugate/Tag/Label :

PURE

Immunogen :

Recombinant human TMEM119 protein (extracellular domain)

Application Notes :

For microscopy, the antibody was found to work best when using fresh frozen human tissues. Communication by Dr. Frederick Christian Bennett at Stanford University, under review in Neuron.;*The human TMEM119 full length plasmid was a courtesy gift from Dr. Ben Barres at Stanford University.;

more info or order :

BioLegend product webpage