Purified anti-TMEM119 (Extracellular) | BioLegend 853301 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

Purified anti-TMEM119 (Extracellular)

catalog :

853301

quantity :

25 μg

price :

112 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

A16075D

reactivity :

human

application :

western blot, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section

more info or order :

BioLegend product webpage

citations: 10

Reference
Tang Y, Chaillon A, Gianella S, Wong L, Li D, Simermeyer T, et al. Brain microglia serve as a persistent HIV reservoir despite durable antiretroviral therapy. J Clin Invest. 2023;133: pubmed publisher
Patel T, Carnwath T, Wang X, Allen M, Lincoln S, Lewis Tuffin L, et al. Transcriptional landscape of human microglia implicates age, sex, and APOE-related immunometabolic pathway perturbations. Aging Cell. 2022;21:e13606 pubmed publisher
Toedebusch R, Lucchesi C, Debebe E, Wittenburg L, Chen X, Toedebusch C. Microglia-Derived Olfactomedin-like 3 Promotes Pro-Tumorigenic Microglial Function and Malignant Features of Glioma Cells. Int J Mol Sci. 2021;22: pubmed publisher
Bodnar B, Zhang Y, Liu J, Lin Y, Wang P, Wei Z, et al. Novel Scalable and Simplified System to Generate Microglia-Containing Cerebral Organoids From Human Induced Pluripotent Stem Cells. Front Cell Neurosci. 2021;15:682272 pubmed publisher
Yeini E, Ofek P, Pozzi S, Albeck N, Ben Shushan D, Tiram G, et al. P-selectin axis plays a key role in microglia immunophenotype and glioblastoma progression. Nat Commun. 2021;12:1912 pubmed publisher
Kumar A, Kim S, Su Y, Sharma M, Kumar P, Singh S, et al. Brain cell-derived exosomes in plasma serve as neurodegeneration biomarkers in male cynomolgus monkeys self-administrating oxycodone. EBioMedicine. 2021;63:103192 pubmed publisher
Rai M, Hammonds J, Pujato M, Mayhew C, Roskin K, Spearman P. Comparative analysis of human microglial models for studies of HIV replication and pathogenesis. Retrovirology. 2020;17:35 pubmed publisher
Chen P, Hsu W, Chang A, Tan Z, Lan Z, Zhou A, et al. Circadian Regulator CLOCK Recruits Immune-Suppressive Microglia into the GBM Tumor Microenvironment. Cancer Discov. 2020;10:371-381 pubmed publisher
Ruan C, Sun L, Kroshilina A, Beckers L, De Jager P, Bradshaw E, et al. A novel Tmem119-tdTomato reporter mouse model for studying microglia in the central nervous system. Brain Behav Immun. 2020;83:180-191 pubmed publisher
Bennett F, Bennett M, Yaqoob F, Mulinyawe S, Grant G, Hayden Gephart M, et al. A Combination of Ontogeny and CNS Environment Establishes Microglial Identity. Neuron. 2018;98:1170-1183.e8 pubmed publisher

product information

Antigen :

TMEM119

Apps. Abbrev. :

FC, WB, ICC, IHC-P

Cat # :

853301

Clone :

A16075D

Item :

Purified anti-TMEM119 (Extracellular)

Isotype :

Mouse IgG2b, κ

Other Names :

Transmembrane protein 119

Size :

25 μg

Price (USD) :

112 USD

Reactivity :

Human

Clonality :

Monoclonal

Host :

Mouse

Conjugate/Tag/Label :

PURE

Immunogen :

Recombinant human TMEM119 protein (extracellular domain)

Application Notes :

For microscopy, the antibody was found to work best when using fresh frozen human tissues. Communication by Dr. Frederick Christian Bennett at Stanford University, under review in Neuron.;*The human TMEM119 full length plasmid was a courtesy gift from Dr. Ben Barres at Stanford University.;

more info or order :

BioLegend product webpage