anti-CD171 (L1CAM) | BioLegend 838101 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

anti-CD171 (L1CAM)

catalog :

838101

quantity :

500 μL

price :

433 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

74-5H7

reactivity :

human, mouse, rat

application :

western blot, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section

more info or order :

BioLegend product webpage

citations: 4

Reference
Hu J, Lin S, Schachner M. A fragment of cell adhesion molecule L1 reduces amyloid-β plaques in a mouse model of Alzheimer's disease. Cell Death Dis. 2022;13:48 pubmed publisher
Kleene R, Lutz D, Loers G, Bork U, Borgmeyer U, Hermans Borgmeyer I, et al. Revisiting the proteolytic processing of cell adhesion molecule L1. J Neurochem. 2021;157:1102-1117 pubmed publisher
Girbes Minguez M, Wolters Eisfeld G, Lutz D, Buck F, Schachner M, Kleene R. The cell adhesion molecule L1 interacts with nuclear proteins via its intracellular domain. FASEB J. 2020;34:9869-9883 pubmed publisher
Chen S, Wilkemeyer M, Sulik K, Charness M. Octanol antagonism of ethanol teratogenesis. FASEB J. 2001;15:1649-51 pubmed

product information

Antigen :

CD171

Apps. Abbrev. :

WB, ICC, IP, IHC-P

Cat # :

838101

Clone :

74-5H7

Item :

anti-CD171 (L1CAM)

Isotype :

Mouse IgG1, κ

Other Names :

Neural cell adhesion molecule L1, antigen identified by monoclonal antibody R1

Size :

500 μL

Price (USD) :

433 USD

Reactivity :

Human, Mouse, Rat

Clonality :

Monoclonal

Host :

Mouse

Conjugate/Tag/Label :

ASCITES

Immunogen :

This monoclonal antibody was raised against purified chick L1, and binds to the L1 cytoplasmic domain at about T1172 (adjacent to the YRSL sorting signal).

Application Notes :

Phosphorylation of either T1172 or Y1176 strongly inhibits binding of 74-5H7 to the L1 cytoplasmic domain.

more info or order :

BioLegend product webpage