Alexa Fluor® 594 anti-O-GlcNAc | BioLegend 838006 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

Alexa Fluor® 594 anti-O-GlcNAc

catalog :

838006

quantity :

100 μg

price :

405 USD

clonality :

monoclonal

host :

mouse

conjugate :

Alexa Fluor 594

clone name :

CTD110.6

reactivity :

human, mouse

application :

western blot, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

citations: 9

Published Application/Species/Sample/Dilution	Reference
western blot; human; loading ...; fig 1e	Guo H, Zhang B, Nairn A, Nagy T, Moremen K, Buckhaults P, et al. O-Linked N-Acetylglucosamine (O-GlcNAc) Expression Levels Epigenetically Regulate Colon Cancer Tumorigenesis by Affecting the Cancer Stem Cell Compartment via Modulating Expression of Transcriptional Factor MYBL1. J Biol Chem. 2017;292:4123-4137 pubmed publisher
western blot; human; loading ...; fig 1b	Someya A, Ikegami T, Sakamoto K, Nagaoka I. Glucosamine Downregulates the IL-1?-Induced Expression of Proinflammatory Cytokine Genes in Human Synovial MH7A Cells by O-GlcNAc Modification-Dependent and -Independent Mechanisms. PLoS ONE. 2016;11:e0165158 pubmed publisher
immunohistochemistry - frozen section; mouse; loading ...; fig 4a western blot; mouse; fig 1b	Borghgraef P, Menuet C, Theunis C, Louis J, Devijver H, Maurin H, et al. Increasing brain protein O-GlcNAc-ylation mitigates breathing defects and mortality of Tau.P301L mice. PLoS ONE. 2013;8:e84442 pubmed publisher
	Hagan N, Kane J, Grover D, Woodworth L, Madore C, Saleh J, et al. CSF1R signaling is a regulator of pathogenesis in progressive MS. Cell Death Dis. 2020;11:904 pubmed publisher
	Choi H, Kim C, Song H, Cha M, Cho H, Son S, et al. Amyloid β-induced elevation of O-GlcNAcylated c-Fos promotes neuronal cell death. Aging Cell. 2019;18:e12872 pubmed publisher
	Hao X, Li Y, Wang J, Ma J, Zhao S, Ye X, et al. Deficient O-GlcNAc Glycosylation Impairs Regulatory T Cell Differentiation and Notch Signaling in Autoimmune Hepatitis. Front Immunol. 2018;9:2089 pubmed publisher
	Nugent B, O Donnell C, Epperson C, Bale T. Placental H3K27me3 establishes female resilience to prenatal insults. Nat Commun. 2018;9:2555 pubmed publisher
	Kim N, Cha Y, Lee J, Lee S, Yang J, Yun J, et al. Snail reprograms glucose metabolism by repressing phosphofructokinase PFKP allowing cancer cell survival under metabolic stress. Nat Commun. 2017;8:14374 pubmed publisher
	Chen Y, Chen C, Liang C, Liang J, Tai M, Chang Y, et al. Silibinin inhibits ICAM-1 expression via regulation of N-linked and O-linked glycosylation in ARPE-19 cells. Biomed Res Int. 2014;2014:701395 pubmed publisher

product information

Antigen :

O-GlcNAc

Apps. Abbrev. :

IHC-P

Cat # :

838006

Clone :

CTD110.6

Item :

Alexa Fluor® 594 anti-O-GlcNAc

Isotype :

Mouse IgM, κ

Other Names :

O-Linked N-Acetylglucosamine

Size :

100 μg

Price (USD) :

405 USD

Reactivity :

All Species

Clonality :

Monoclonal

Host :

Mouse

Conjugate/Tag/Label :

A594

Immunogen :

The antibody was raised against a synthetic peptide containing Serine-O-GlcNAc.

Application Notes :

This antibody detects Ser-O-GlcNAc and Thr-O-GlcNAc but shows no cross-reactivity with peptide determinants or other closely-related carbohydrate antigens. Interaction between the antibody and the Ser- or Thr-O-GlcNAc epitope can be blocked by competition with free GlcNAc. Milk proteins may cross-react with the antibody therefore we recommend using BSA or goat serum as a blocker. Additional reported applications (for the relevant formats) include: ELISA 2 , immunocytochemistry 7 , immunoprecipitation 2,5,6 , and Western blotting 3,4,7 .