product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
Anti-GFAP (Cocktail)
catalog :
837602
quantity :
500 μL
price :
483 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
SMI 26
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section
more info or order :
citations: 9
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry; mouse; 1:1000; fig 1
Heaven M, Flint D, Randall S, Sosunov A, Wilson L, Barnes S, et al. Composition of Rosenthal Fibers, the Protein Aggregate Hallmark of Alexander Disease. J Proteome Res. 2016;15:2265-82 pubmed publisher
Rosen G, Kirsch D, Nicks R, Kelley H, Mathias R, Cormier K, et al. SHARD: an improved method for staining and visualizing multiplex immunofluorescence in optically cleared postmortem human brain tissue. Front Neurosci. 2024;18:1474617 pubmed publisher
Hagemann T, Coyne S, Levin A, Wang L, Feany M, Messing A. STAT3 Drives GFAP Accumulation and Astrocyte Pathology in a Mouse Model of Alexander Disease. Cells. 2023;12: pubmed publisher
Lutgen V, Narasipura S, Barbian H, Richards M, Wallace J, Razmpour R, et al. HIV infects astrocytes in vivo and egresses from the brain to the periphery. PLoS Pathog. 2020;16:e1008381 pubmed publisher
Vallvé Juanico J, Santamaria X, Vo K, Houshdaran S, Giudice L. Macrophages display proinflammatory phenotypes in the eutopic endometrium of women with endometriosis with relevance to an infectious etiology of the disease. Fertil Steril. 2019;112:1118-1128 pubmed publisher
Calabretta S, Vogel G, Yu Z, Choquet K, Darbelli L, Nicholson T, et al. Loss of PRMT5 Promotes PDGFR? Degradation during Oligodendrocyte Differentiation and Myelination. Dev Cell. 2018;46:426-440.e5 pubmed publisher
Moody L, Barrett Wilt G, Sussman M, Messing A. Glial fibrillary acidic protein exhibits altered turnover kinetics in a mouse model of Alexander disease. J Biol Chem. 2017;292:5814-5824 pubmed publisher
Lin N, Huang Y, Opal P, Goldman R, Messing A, Perng M. The role of gigaxonin in the degradation of the glial-specific intermediate filament protein GFAP. Mol Biol Cell. 2016;27:3980-3990 pubmed
Chen M, Hagemann T, Quinlan R, Messing A, Perng M. Caspase cleavage of GFAP produces an assembly-compromised proteolytic fragment that promotes filament aggregation. ASN Neuro. 2013;5:e00125 pubmed publisher
product information
Antigen :
GFAP
Apps. Abbrev. :
IHC-P, WB, ICC
Cat # :
837602
Clone :
SMI 26
Item :
Anti-GFAP (Cocktail)
Isotype :
Mouse IgG1/Mouse IgG2b
Other Names :
Glial fibrillary acidic protein
Size :
500 μL
Price (USD) :
483 USD
Reactivity :
Human, Mouse, Rat
Clonality :
Monoclonal
Host :
Mouse
Conjugate/Tag/Label :
ASCITES
Application Notes :
Antibody is less reactive in mouse tissue in IHC-P.Multiple protein fragments ranging from 38 to 48 kD have been reported in human CNS lysates resulting from caspase- and calpain-mediated cleavage of GFAP.;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA