product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
Purified anti-GFAP
catalog :
837204
quantity :
100 μg
price :
276 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
SMI 21
reactivity :
human, mouse, dogs
application :
western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
citations: 11
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - frozen section; human; 1:500; loading ...; fig 2e
Li J, Pan L, Pembroke W, Rexach J, Godoy M, Condro M, et al. Conservation and divergence of vulnerability and responses to stressors between human and mouse astrocytes. Nat Commun. 2021;12:3958 pubmed publisher
  • immunocytochemistry; human; 1:400; loading ...; tbl 1
  • western blot; human; 1:5000; loading ...; tbl 1
  • immunocytochemistry; mouse; 1:400; loading ...; tbl 1
  • western blot; mouse; 1:5000; loading ...; tbl 1
Lin N, Messing A, Perng M. Characterization of a panel of monoclonal antibodies recognizing specific epitopes on GFAP. PLoS ONE. 2017;12:e0180694 pubmed publisher
  • western blot; human; fig 3a
Jung J, Kim L, Wang X, Wu Q, Sanvoranart T, Hubert C, et al. Nicotinamide metabolism regulates glioblastoma stem cell maintenance. JCI Insight. 2017;2: pubmed publisher
  • immunohistochemistry; mouse; 1:1000; loading ...; fig s4c
Ehrlich M, Mozafari S, Glatza M, Starost L, Velychko S, Hallmann A, et al. Rapid and efficient generation of oligodendrocytes from human induced pluripotent stem cells using transcription factors. Proc Natl Acad Sci U S A. 2017;114:E2243-E2252 pubmed publisher
Turovsky E, Varlamova E, Plotnikov E. Mechanisms Underlying the Protective Effect of the Peroxiredoxin-6 Are Mediated via the Protection of Astrocytes during Ischemia/Reoxygenation. Int J Mol Sci. 2021;22: pubmed publisher
Turovsky E, Turovskaya M, Fedotova E, Babaev A, Tarabykin V, Varlamova E. Role of Satb1 and Satb2 Transcription Factors in the Glutamate Receptors Expression and Ca2+ Signaling in the Cortical Neurons In Vitro. Int J Mol Sci. 2021;22: pubmed publisher
Hagan N, Kane J, Grover D, Woodworth L, Madore C, Saleh J, et al. CSF1R signaling is a regulator of pathogenesis in progressive MS. Cell Death Dis. 2020;11:904 pubmed publisher
Wang J, Saraswat D, Sinha A, Polanco J, Dietz K, O Bara M, et al. Paired Related Homeobox Protein 1 Regulates Quiescence in Human Oligodendrocyte Progenitors. Cell Rep. 2018;25:3435-3450.e6 pubmed publisher
Park N, Guilhamon P, Desai K, McAdam R, Langille E, O Connor M, et al. ASCL1 Reorganizes Chromatin to Direct Neuronal Fate and Suppress Tumorigenicity of Glioblastoma Stem Cells. Cell Stem Cell. 2017;21:209-224.e7 pubmed publisher
Choi V, Bigelow C, McGee T, Gujar A, Li H, Hanks S, et al. AAV-mediated RLBP1 gene therapy improves the rate of dark adaptation in Rlbp1 knockout mice. Mol Ther Methods Clin Dev. 2015;2:15022 pubmed publisher
Chort A, Alves S, Marinello M, Dufresnois B, Dornbierer J, Tesson C, et al. Interferon ? induces clearance of mutant ataxin 7 and improves locomotion in SCA7 knock-in mice. Brain. 2013;136:1732-45 pubmed publisher
product information
Antigen :
GFAP
Apps. Abbrev. :
IHC-P, WB, ICC
Cat # :
837204
Clone :
SMI 21
Item :
Purified anti-GFAP
Isotype :
Mouse IgG1, κ
Other Names :
Glial fibrillary acidic protein
Size :
100 μg
Price (USD) :
276 USD
Reactivity :
Human, Non-Human Primate, Dog
Clonality :
Monoclonal
Host :
Mouse
Conjugate/Tag/Label :
PURE
Immunogen :
Human brain micro vessels.
Application Notes :
SMI 21 has been tested for immunocytochemical localization of GFAP in astrocytes and Bergmann glia in human, monkey and dog paraffin sections. Astrocytomas from human and dog show a positive reaction with SMI 21. Rat, rabbit and mouse brain sections do not react with SMI 21. Other species have not been examined. SMI 21 shows no cross reactivity with other intermediate filaments in tissue sections or Western blot lysates derived from human or rat brain tissue.;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA