product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
Purified anti-SNAP-25
catalog :
836303
quantity :
25 μg
price :
112 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
SMI 81
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section
more info or order :
citations: 27
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; loading ...; fig s1
Silverman J, Christy D, Shyu C, Moon K, Fernando S, Gidden Z, et al. CNS-derived extracellular vesicles from superoxide dismutase 1 (SOD1)G93A ALS mice originate from astrocytes and neurons and carry misfolded SOD1. J Biol Chem. 2019;294:3744-3759 pubmed publisher
  • western blot; mouse; loading ...; fig ev2f
Fossati G, Pozzi D, Canzi A, Mirabella F, Valentino S, Morini R, et al. Pentraxin 3 regulates synaptic function by inducing AMPA receptor clustering via ECM remodeling and β1-integrin. EMBO J. 2019;38: pubmed publisher
  • immunohistochemistry; mouse; loading ...; fig s6a
Wallrapp A, Riesenfeld S, Burkett P, Abdulnour R, Nyman J, Dionne D, et al. The neuropeptide NMU amplifies ILC2-driven allergic lung inflammation. Nature. 2017;549:351-356 pubmed publisher
Wang Q, Wolf A, Ozkan S, Richert L, Mely Y, Chasserot Golaz S, et al. V-ATPase modulates exocytosis in neuroendocrine cells through the activation of the ARNO-Arf6-PLD pathway and the synthesis of phosphatidic acid. Front Mol Biosci. 2023;10:1163545 pubmed publisher
Junakovi x107 A, Kopi x107 J, Duque A, Rakic P, Krsnik x, Kostovi x107 I. Laminar dynamics of deep projection neurons and mode of subplate formation are hallmarks of histogenetic subdivisions of the human cingulate cortex before onset of arealization. Brain Struct Funct. 2023;228:613-633 pubmed publisher
Xie Y, Naseri N, Fels J, Kharel P, Na Y, Lane D, et al. Lysosomal exocytosis releases pathogenic α-synuclein species from neurons in synucleinopathy models. Nat Commun. 2022;13:4918 pubmed publisher
Carnazza K, Komer L, Xie Y, Pineda A, Briano J, Gao V, et al. Synaptic vesicle binding of α-synuclein is modulated by β- and γ-synucleins. Cell Rep. 2022;39:110675 pubmed publisher
Wang W, Kong M, Dou Y, Xue S, Liu Y, Zhang Y, et al. Selective Expression of a SNARE-Cleaving Protease in Peripheral Sensory Neurons Attenuates Pain-Related Gene Transcription and Neuropeptide Release. Int J Mol Sci. 2021;22: pubmed publisher
Wilhelmi I, Grunwald S, Gimber N, Popp O, Dittmar G, Arumughan A, et al. The ARFRP1-dependent Golgi scaffolding protein GOPC is required for insulin secretion from pancreatic β-cells. Mol Metab. 2021;45:101151 pubmed publisher
Chew L, Ming X, McEllin B, Dupree J, Hong E, Catron M, et al. Sox17 Regulates a Program of Oligodendrocyte Progenitor Cell Expansion and Differentiation during Development and Repair. Cell Rep. 2019;29:3173-3186.e7 pubmed publisher
Marcelli S, Iannuzzi F, Ficulle E, Mango D, Pieraccini S, Pellegrino S, et al. The selective disruption of presynaptic JNK2/STX1a interaction reduces NMDA receptor-dependent glutamate release. Sci Rep. 2019;9:7146 pubmed publisher
Stewart M, Lau P, Banks G, Bains R, Castroflorio E, Oliver P, et al. Loss of Frrs1l disrupts synaptic AMPA receptor function, and results in neurodevelopmental, motor, cognitive and electrographical abnormalities. Dis Model Mech. 2019;12: pubmed publisher
Fuschini G, Cotrufo T, Ros O, Muhaisen A, Andres R, Comella J, et al. Syntaxin-1/TI-VAMP SNAREs interact with Trk receptors and are required for neurotrophin-dependent outgrowth. Oncotarget. 2018;9:35922-35940 pubmed publisher
Kandachar V, Tam B, Moritz O, Deretic D. An interaction network between the SNARE VAMP7 and Rab GTPases within a ciliary membrane-targeting complex. J Cell Sci. 2018;131: pubmed publisher
Lienbacher K, Ono S, Fleuriet J, MUSTARI M, Horn A. A Subset of Palisade Endings Only in the Medial and Inferior Rectus Muscle in Monkey Contain Calretinin. Invest Ophthalmol Vis Sci. 2018;59:2944-2954 pubmed publisher
Konstantinović J, Kiris E, Kota K, Kugelman Tonos J, Videnović M, Cazares L, et al. New Steroidal 4-Aminoquinolines Antagonize Botulinum Neurotoxin Serotype A in Mouse Embryonic Stem Cell Derived Motor Neurons in Postintoxication Model. J Med Chem. 2018;61:1595-1608 pubmed publisher
Prada I, Gabrielli M, Turola E, Iorio A, D Arrigo G, Parolisi R, et al. Glia-to-neuron transfer of miRNAs via extracellular vesicles: a new mechanism underlying inflammation-induced synaptic alterations. Acta Neuropathol. 2018;135:529-550 pubmed publisher
Klose C, Mahlakõiv T, Moeller J, Rankin L, Flamar A, Kabata H, et al. The neuropeptide neuromedin U stimulates innate lymphoid cells and type 2 inflammation. Nature. 2017;549:282-286 pubmed publisher
Santos T, Wierda K, Broeke J, Toonen R, Verhage M. Early Golgi Abnormalities and Neurodegeneration upon Loss of Presynaptic Proteins Munc18-1, Syntaxin-1, or SNAP-25. J Neurosci. 2017;37:4525-4539 pubmed publisher
Kunii M, Ohara Imaizumi M, Takahashi N, Kobayashi M, Kawakami R, Kondoh Y, et al. Opposing roles for SNAP23 in secretion in exocrine and endocrine pancreatic cells. J Cell Biol. 2016;215:121-138 pubmed
Gu Y, Chiu S, Liu B, Wu P, Delannoy M, Lin D, et al. Differential vesicular sorting of AMPA and GABAA receptors. Proc Natl Acad Sci U S A. 2016;113:E922-31 pubmed publisher
Kabachinski G, Kielar Grevstad D, Zhang X, James D, Martin T. Resident CAPS on dense-core vesicles docks and primes vesicles for fusion. Mol Biol Cell. 2016;27:654-68 pubmed publisher
Brinkmalm A, Brinkmalm G, Honer W, Frölich L, Hausner L, Minthon L, et al. SNAP-25 is a promising novel cerebrospinal fluid biomarker for synapse degeneration in Alzheimer's disease. Mol Neurodegener. 2014;9:53 pubmed publisher
Burré J, Sharma M, Sudhof T. Systematic mutagenesis of ?-synuclein reveals distinct sequence requirements for physiological and pathological activities. J Neurosci. 2012;32:15227-42 pubmed publisher
Rozas J, Gómez Sánchez L, Mircheski J, Linares Clemente P, Nieto Gonzalez J, Vazquez M, et al. Motorneurons require cysteine string protein-? to maintain the readily releasable vesicular pool and synaptic vesicle recycling. Neuron. 2012;74:151-65 pubmed publisher
Hirano A, Brandstätter J, Morgans C, Brecha N. SNAP25 expression in mammalian retinal horizontal cells. J Comp Neurol. 2011;519:972-88 pubmed publisher
Flores Otero J, Xue H, Davis R. Reciprocal regulation of presynaptic and postsynaptic proteins in bipolar spiral ganglion neurons by neurotrophins. J Neurosci. 2007;27:14023-34 pubmed
product information
Antigen :
SNAP-25
Apps. Abbrev. :
IHC-P, WB, EM, FC, ICC, IP
Cat # :
836303
Clone :
SMI 81
Item :
Purified anti-SNAP-25
Isotype :
Mouse IgG1, κ
Other Names :
Synaptosomal-associated protein 25, SUP, Synaptosomal-associated 25 kD Protein
Size :
25 μg
Price (USD) :
112 USD
Reactivity :
Human, Mouse, Rat
Clonality :
Monoclonal
Host :
Mouse
Conjugate/Tag/Label :
PURE
Immunogen :
Full length, unaltered SNAP-25
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA