product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
Anti-GFAP (Cocktail)
catalog :
835301
quantity :
100 μL
price :
310 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
SMI 22
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
citations: 24
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - frozen section; mouse; 1:1000; loading ...; fig 1b, 3f
Evonuk K, Doyle R, Moseley C, Thornell I, Adler K, Bingaman A, et al. Reduction of AMPA receptor activity on mature oligodendrocytes attenuates loss of myelinated axons in autoimmune neuroinflammation. Sci Adv. 2020;6:eaax5936 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:1000; loading ...; fig 5b
Hu X, Das B, Hou H, He W, Yan R. BACE1 deletion in the adult mouse reverses preformed amyloid deposition and improves cognitive functions. J Exp Med. 2018;215:927-940 pubmed publisher
  • immunohistochemistry; mouse; loading ...; fig st1
Ku T, Swaney J, Park J, Albanese A, Murray E, Cho J, et al. Multiplexed and scalable super-resolution imaging of three-dimensional protein localization in size-adjustable tissues. Nat Biotechnol. 2016;34:973-81 pubmed publisher
  • immunohistochemistry; mouse; fig 1
Miyamoto Y, Torii T, Takada S, Ohno N, Saitoh Y, Nakamura K, et al. Involvement of the Tyro3 receptor and its intracellular partner Fyn signaling in Schwann cell myelination. Mol Biol Cell. 2015;26:3489-503 pubmed publisher
  • immunohistochemistry; human; 1:500
Shaikh H, Lechpammer M, Jensen F, Warfield S, Hansen A, Kosaras B, et al. Increased Brain Perfusion Persists over the First Month of Life in Term Asphyxiated Newborns Treated with Hypothermia: Does it Reflect Activated Angiogenesis?. Transl Stroke Res. 2015;6:224-33 pubmed publisher
  • western blot; mouse
Chou V, Ko N, Holman T, Manning Bog A. Gene-environment interaction models to unmask susceptibility mechanisms in Parkinson's disease. J Vis Exp. 2014;:e50960 pubmed publisher
  • immunohistochemistry; rat; 1:1000
Bourque S, Kuny S, Reyes L, Davidge S, Sauve Y. Prenatal hypoxia is associated with long-term retinal dysfunction in rats. PLoS ONE. 2013;8:e61861 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:3000
Desilva T, Borenstein N, Volpe J, Kinney H, Rosenberg P. Expression of EAAT2 in neurons and protoplasmic astrocytes during human cortical development. J Comp Neurol. 2012;520:3912-32 pubmed publisher
  • immunohistochemistry; rat; 1:1,000
Talos D, Fishman R, Park H, Folkerth R, Follett P, Volpe J, et al. Developmental regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid receptor subunit expression in forebrain and relationship to regional susceptibility to hypoxic/ischemic injury. I. Rodent cerebral white matter and cortex. J Comp Neurol. 2006;497:42-60 pubmed
Khan S, Takeuchi A, Nabeka H, Khan F, Shimokawa T, Takanezawa S, et al. Administration of prosaposin-derived neurotrophic factor to neural tube defects facilitates regeneration and restores neurological functions. iScience. 2023;26:106277 pubmed publisher
Saleh B, Srikanth K, Sneh T, Yue L, Pelech S, Elliott E, et al. FAK-Mediated Signaling Controls Amyloid Beta Overload, Learning and Memory Deficits in a Mouse Model of Alzheimer's Disease. Int J Mol Sci. 2022;23: pubmed publisher
Boscher E, Goupil C, Petry S, Keraudren R, Loiselle A, Planel E, et al. MicroRNA-138 Overexpression Alters Aβ42 Levels and Behavior in Wildtype Mice. Front Neurosci. 2020;14:591138 pubmed publisher
Huang S, Choi M, Huang H, Wang X, Chang Y, Kim J. Demyelination Regulates the Circadian Transcription Factor BMAL1 to Signal Adult Neural Stem Cells to Initiate Oligodendrogenesis. Cell Rep. 2020;33:108394 pubmed publisher
Wei W, Wang Y, Liu Y, Dai C, Tung Y, Liu F, et al. Prenatal to early postnatal neurotrophic treatment prevents Alzheimer-like behavior and pathology in mice. Alzheimers Res Ther. 2020;12:102 pubmed publisher
Abey A, Davies D, Goldsbury C, Buckland M, Valenzuela M, Duncan T. Distribution of tau hyperphosphorylation in canine dementia resembles early Alzheimer's disease and other tauopathies. Brain Pathol. 2021;31:144-162 pubmed publisher
Lutgen V, Narasipura S, Barbian H, Richards M, Wallace J, Razmpour R, et al. HIV infects astrocytes in vivo and egresses from the brain to the periphery. PLoS Pathog. 2020;16:e1008381 pubmed publisher
Care R, Kastner D, De la Huerta I, Pan S, Khoche A, Della Santina L, et al. Partial Cone Loss Triggers Synapse-Specific Remodeling and Spatial Receptive Field Rearrangements in a Mature Retinal Circuit. Cell Rep. 2019;27:2171-2183.e5 pubmed publisher
Polis B, Srikanth K, Elliott E, Gil Henn H, Samson A. L-Norvaline Reverses Cognitive Decline and Synaptic Loss in a Murine Model of Alzheimer's Disease. Neurotherapeutics. 2018;15:1036-1054 pubmed publisher
Zelikoff J, Parmalee N, Corbett K, Gordon T, Klein C, Aschner M. Microglia Activation and Gene Expression Alteration of Neurotrophins in the Hippocampus Following Early Life Exposure to E-cigarette Aerosols in a Murine Model. Toxicol Sci. 2017;: pubmed publisher
Lin N, Huang Y, Opal P, Goldman R, Messing A, Perng M. The role of gigaxonin in the degradation of the glial-specific intermediate filament protein GFAP. Mol Biol Cell. 2016;27:3980-3990 pubmed
Yu K, Kuzum D, Hwang S, Kim B, Juul H, Kim N, et al. Bioresorbable silicon electronics for transient spatiotemporal mapping of electrical activity from the cerebral cortex. Nat Mater. 2016;15:782-791 pubmed publisher
Kanno H, Pressman Y, Moody A, Berg R, Muir E, Rogers J, et al. Combination of engineered Schwann cell grafts to secrete neurotrophin and chondroitinase promotes axonal regeneration and locomotion after spinal cord injury. J Neurosci. 2014;34:1838-55 pubmed publisher
Jiang H, He P, Adler C, Shill H, Beach T, Li R, et al. Bid signal pathway components are identified in the temporal cortex with Parkinson disease. Neurology. 2012;79:1767-73 pubmed publisher
Traka M, Wollmann R, Cerda S, Dugas J, Barres B, Popko B. Nur7 is a nonsense mutation in the mouse aspartoacylase gene that causes spongy degeneration of the CNS. J Neurosci. 2008;28:11537-49 pubmed publisher
product information
Antigen :
GFAP
Apps. Abbrev. :
IHC-P, WB, ICC
Cat # :
835301
Clone :
SMI 22
Item :
Anti-GFAP (Cocktail)
Isotype :
Mouse IgG2b
Other Names :
Glial fibrillary acidic protein
Size :
100 μL
Price (USD) :
310 USD
Reactivity :
Human, Mouse, Rat
Clonality :
Monoclonal
Host :
Mouse
Conjugate/Tag/Label :
ASCITES
Application Notes :
Multiple protein fragments ranging from 38 to 48 kD have been reported in human CNS lysates resulting from caspase- and calpain-mediated cleavage of GFAP.;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA