| Published Application/Species/Sample/Dilution | Reference |
|---|
- immunocytochemistry; human; loading ...; fig 4a
- western blot; human; loading ...; fig 2c
| Amaral A, Perez Nievas B, Siao Tick Chong M, González Martínez A, Argente Escrig H, Rubio Guerra S, et al. Isoform-selective decrease of glycogen synthase kinase-3-beta (GSK-3β) reduces synaptic tau phosphorylation, transcellular spreading, and aggregation. iScience. 2021;24:102058 pubmed publisher |
- immunohistochemistry - free floating section; mouse; 1:200; loading ...; fig 4d
| Rauch J, Luna G, Guzman E, Audouard M, Challis C, Sibih Y, et al. LRP1 is a master regulator of tau uptake and spread. Nature. 2020;580:381-385 pubmed publisher |
- western blot; human; 1:50,000; fig 1a
| Lo Cascio F, Puangmalai N, Ellsworth A, Bucchieri F, Pace A, Palumbo Piccionello A, et al. Toxic Tau Oligomers Modulated by Novel Curcumin Derivatives. Sci Rep. 2019;9:19011 pubmed publisher |
- western blot; human; 1:2000; fig 3
| Takeda S, Commins C, DeVos S, Nobuhara C, Wegmann S, Roe A, et al. Seed-competent high-molecular-weight tau species accumulates in the cerebrospinal fluid of Alzheimer's disease mouse model and human patients. Ann Neurol. 2016;80:355-67 pubmed publisher |
- western blot; human; 1:2000
| Henstridge C, Jackson R, Kim J, Herrmann A, Wright A, Harris S, et al. Post-mortem brain analyses of the Lothian Birth Cohort 1936: extending lifetime cognitive and brain phenotyping to the level of the synapse. Acta Neuropathol Commun. 2015;3:53 pubmed publisher |
| Zhong S, Ye J, Deng Y, Zhang M, Zou M, Yao X, et al. Quercetagitrin Inhibits Tau Accumulation and Reverses Neuroinflammation and Cognitive Deficits in P301S-Tau Transgenic Mice. Molecules. 2023;28: pubmed publisher |
| Polanco J, Akimov Y, Fernandes A, Briner A, Hand G, van Roijen M, et al. CRISPRi screening reveals regulators of tau pathology shared between exosomal and vesicle-free tau. Life Sci Alliance. 2023;6: pubmed publisher |
| Zhu B, Liu Y, Hwang S, Archuleta K, Huang H, Campos A, et al. Trem2 deletion enhances tau dispersion and pathology through microglia exosomes. Mol Neurodegener. 2022;17:58 pubmed publisher |
| Steuer E, Kemper L, Hlynialuk C, Leinonen Wright K, Montonye M, Lapcinski I, et al. Blocking Site-Specific Cleavage of Human Tau Delays Progression of Disease-Related Phenotypes in Genetically Matched Tau-Transgenic Mice Modeling Frontotemporal Dementia. J Neurosci. 2022;42:4737-4754 pubmed publisher |
| Hochmair J, Exner C, Franck M, Dominguez Baquero A, Diez L, Brognaro H, et al. Molecular crowding and RNA synergize to promote phase separation, microtubule interaction, and seeding of Tau condensates. EMBO J. 2022;41:e108882 pubmed publisher |
| Gerson J, Sandoval Pistorius S, Welday J, Rodriguez A, Gregory J, Liggans N, et al. Disrupting the Balance of Protein Quality Control Protein UBQLN2 Accelerates Tau Proteinopathy. J Neurosci. 2022;42:1845-1863 pubmed publisher |
| Bresinsky M, Strasser J, Vallaster B, Liu P, McCue W, Fuller J, et al. Structure-Based Design and Biological Evaluation of Novel Caspase-2 Inhibitors Based on the Peptide AcVDVAD-CHO and the Caspase-2-Mediated Tau Cleavage Sequence YKPVD314. ACS Pharmacol Transl Sci. 2022;5:20-40 pubmed publisher |
| Rasmussen J, Ewing A, Bodea L, Bodea G, Gearing M, Faulkner G. An early proinflammatory transcriptional response to tau pathology is age-specific and foreshadows reduced tau burden. Brain Pathol. 2022;32:e13018 pubmed publisher |
| Filip T, Mairinger S, Neddens J, Sauberer M, Flunkert S, Stanek J, et al. Characterization of an APP/tau rat model of Alzheimer's disease by positron emission tomography and immunofluorescent labeling. Alzheimers Res Ther. 2021;13:175 pubmed publisher |
| Han J, Park H, Maharana C, Gwon A, Park J, Baek S, et al. Alzheimer's disease-causing presenilin-1 mutations have deleterious effects on mitochondrial function. Theranostics. 2021;11:8855-8873 pubmed publisher |
| McCreedy D, Jalufka F, Platt M, Min S, Kirchhoff M, Pritchard A, et al. Passive Clearing and 3D Lightsheet Imaging of the Intact and Injured Spinal Cord in Mice. Front Cell Neurosci. 2021;15:684792 pubmed publisher |
| Farmer K, Ghag G, Puangmalai N, Montalbano M, Bhatt N, Kayed R. P53 aggregation, interactions with tau, and impaired DNA damage response in Alzheimer's disease. Acta Neuropathol Commun. 2020;8:132 pubmed publisher |
| Liu P, Smith B, Montonye M, Kemper L, Leinonen Wright K, Nelson K, et al. A soluble truncated tau species related to cognitive dysfunction is elevated in the brain of cognitively impaired human individuals. Sci Rep. 2020;10:3869 pubmed publisher |
| Pickett E, Herrmann A, McQueen J, Abt K, Dando O, Tulloch J, et al. Amyloid Beta and Tau Cooperate to Cause Reversible Behavioral and Transcriptional Deficits in a Model of Alzheimer's Disease. Cell Rep. 2019;29:3592-3604.e5 pubmed publisher |
| Liu P, Smith B, Huang E, Mahesh A, Vonsattel J, Petersen A, et al. A soluble truncated tau species related to cognitive dysfunction and caspase-2 is elevated in the brain of Huntington's disease patients. Acta Neuropathol Commun. 2019;7:111 pubmed publisher |
| Crotti A, Sait H, MCAVOY K, Estrada K, Ergun A, Szak S, et al. BIN1 favors the spreading of Tau via extracellular vesicles. Sci Rep. 2019;9:9477 pubmed publisher |
| Busche M, Wegmann S, Dujardin S, Commins C, Schiantarelli J, Klickstein N, et al. Tau impairs neural circuits, dominating amyloid-β effects, in Alzheimer models in vivo. Nat Neurosci. 2019;22:57-64 pubmed publisher |
| Sengupta U, Montalbano M, McAllen S, Minuesa G, Kharas M, Kayed R. Formation of Toxic Oligomeric Assemblies of RNA-binding Protein: Musashi in Alzheimer's disease. Acta Neuropathol Commun. 2018;6:113 pubmed publisher |
| Bennett R, DeVos S, Dujardin S, Corjuc B, Gor R, Gonzalez J, et al. Enhanced Tau Aggregation in the Presence of Amyloid ?. Am J Pathol. 2017;187:1601-1612 pubmed publisher |
| Zhao X, Kotilinek L, Smith B, Hlynialuk C, ZAHS K, Ramsden M, et al. Caspase-2 cleavage of tau reversibly impairs memory. Nat Med. 2016;22:1268-1276 pubmed publisher |
| Fu H, Hussaini S, Wegmann S, Profaci C, Daniels J, Herman M, et al. 3D Visualization of the Temporal and Spatial Spread of Tau Pathology Reveals Extensive Sites of Tau Accumulation Associated with Neuronal Loss and Recognition Memory Deficit in Aged Tau Transgenic Mice. PLoS ONE. 2016;11:e0159463 pubmed publisher |
| Nogueras Ortiz C, De Jesús Cortés H, Vaquer Alicea J, Vega I. Novel autoimmune response in a tauopathy mouse model. Front Neurosci. 2014;7:277 pubmed publisher |
