Purified (azide-free) anti-FMRP | BioLegend 834602 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

Purified (azide-free) anti-FMRP

catalog :

834602

quantity :

25 μL

price :

106 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

6B8/FMRP

reactivity :

human

application :

western blot, immunocytochemistry

more info or order :

BioLegend product webpage

citations: 5

Reference
Yıldırım Z, Baboo S, Hamid S, Dogan A, Tufanlı Ö, Robichaud S, et al. Intercepting IRE1 kinase-FMRP signaling prevents atherosclerosis progression. EMBO Mol Med. 2022;14:e15344 pubmed publisher
Aryal S, Longo F, Klann E. Genetic removal of p70 S6K1 corrects coding sequence length-dependent alterations in mRNA translation in fragile X syndrome mice. Proc Natl Acad Sci U S A. 2021;118: pubmed publisher
Chakraborty A, Jenjaroenpun P, Li J, El Hilali S, McCulley A, Haarer B, et al. Replication Stress Induces Global Chromosome Breakage in the Fragile X Genome. Cell Rep. 2020;32:108179 pubmed publisher
Gustin S, Wang G, Baker V, LATHAM G, Sebastiano V. Use of human-derived stem cells to create a novel, in vitro model designed to explore FMR1 CGG repeat instability amongst female premutation carriers. J Assist Reprod Genet. 2018;35:1443-1455 pubmed publisher
Xie N, Gong H, Suhl J, Chopra P, Wang T, Warren S. Reactivation of FMR1 by CRISPR/Cas9-Mediated Deletion of the Expanded CGG-Repeat of the Fragile X Chromosome. PLoS ONE. 2016;11:e0165499 pubmed publisher

product information

Antigen :

FMRP

Apps. Abbrev. :

WB, ICC

Cat # :

834602

Clone :

6B8/FMRP

Item :

Purified (azide-free) anti-FMRP

Isotype :

Mouse IgG1, κ

Other Names :

Fragile X mental retardation protein 1, POF, FMRP, POF1, FRAXA

Size :

25 μL

Price (USD) :

106 USD

Reactivity :

Human

Clonality :

Monoclonal

Host :

Mouse

Conjugate/Tag/Label :

PUREAF

Immunogen :

This monoclonal antibody was raised against a recombinant protein isolated from baculovirus.

Application Notes :

This antibody is effective in immunoblotting (WB) and immunocytochemistry (ICC).The epitope for 6B8/FMRP lies between amino acids 345-350 of human FMRP. This clone does not cross react with FXR1 or FXR2 and is human specific.This clone is also known as 6B8.;

more info or order :

BioLegend product webpage