product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
Purified (azide-free) anti-Presenilin 1 (NH2 terminus)
catalog :
823401
quantity :
200 μL
price :
501 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
NT1
reactivity :
human
application :
western blot
more info or order :
citations: 14
Published Application/Species/Sample/DilutionReference
  • western blot; human; 1:2000; fig 1
Kretner B, Trambauer J, Fukumori A, Mielke J, Kuhn P, Kremmer E, et al. Generation and deposition of Aβ43 by the virtually inactive presenilin-1 L435F mutant contradicts the presenilin loss-of-function hypothesis of Alzheimer's disease. EMBO Mol Med. 2016;8:458-65 pubmed publisher
Bohl B, Jabali A, Ladewig J, Koch P. Asymmetric Notch activity by differential inheritance of lysosomes in human neural stem cells. Sci Adv. 2022;8:eabl5792 pubmed publisher
Yao H, Hannum D, Zhai Y, Hill S, Albanus R, Lou W, et al. CHD7 promotes neural progenitor differentiation in embryonic stem cells via altered chromatin accessibility and nascent gene expression. Sci Rep. 2020;10:17445 pubmed publisher
Hasenpusch Theil K, Laclef C, Colligan M, Fitzgerald E, Howe K, Carroll E, et al. A transient role of the ciliary gene Inpp5e in controlling direct versus indirect neurogenesis in cortical development. elife. 2020;9: pubmed publisher
Yan P, Liu Z, Song M, Wu Z, Xu W, Li K, et al. Genome-wide R-loop Landscapes during Cell Differentiation and Reprogramming. Cell Rep. 2020;32:107870 pubmed publisher
Roy A, Millen K, Kapur R. Hippocampal granule cell dispersion: a non-specific finding in pediatric patients with no history of seizures. Acta Neuropathol Commun. 2020;8:54 pubmed publisher
Selvadurai H, Luis E, Desai K, Lan X, Vladoiu M, Whitley O, et al. Medulloblastoma Arises from the Persistence of a Rare and Transient Sox2+ Granule Neuron Precursor. Cell Rep. 2020;31:107511 pubmed publisher
Shao W, Yang J, He M, Yu X, Lee C, Yang Z, et al. Centrosome anchoring regulates progenitor properties and cortical formation. Nature. 2020;580:106-112 pubmed publisher
Tomita H, Cornejo F, Aranda Pino B, Woodard C, Rioseco C, Neel B, et al. The Protein Tyrosine Phosphatase Receptor Delta Regulates Developmental Neurogenesis. Cell Rep. 2020;30:215-228.e5 pubmed publisher
Bendriem R, Singh S, Aleem A, Antonetti D, Ross M. Tight junction protein occludin regulates progenitor Self-Renewal and survival in developing cortex. elife. 2019;8: pubmed publisher
Ramme A, Faust D, Koenig L, Marx U. Generation of four integration-free iPSC lines from related human donors. Stem Cell Res. 2019;41:101615 pubmed publisher
Singer R, Arnés L, Cui Y, Wang J, Gao Y, Guney M, et al. The Long Noncoding RNA Paupar Modulates PAX6 Regulatory Activities to Promote Alpha Cell Development and Function. Cell Metab. 2019;30:1091-1106.e8 pubmed publisher
Lee E, Kim N, Park J, Kang K, Kim W, Sim N, et al. Global Analysis of Intercellular Homeodomain Protein Transfer. Cell Rep. 2019;28:712-722.e3 pubmed publisher
Cohen R, Rezai Zadeh K, Weitz T, Rentsendorj A, Gate D, Spivak I, et al. A transgenic Alzheimer rat with plaques, tau pathology, behavioral impairment, oligomeric a?, and frank neuronal loss. J Neurosci. 2013;33:6245-56 pubmed publisher
product information
Antigen :
Presenilin 1 NH2 terminus
Apps. Abbrev. :
WB
Cat # :
823401
Clone :
NT1
Item :
Purified (azide-free) anti-Presenilin 1 (NH2 terminus)
Isotype :
Mouse IgG1
Other Names :
AD3, FAD, PS-1, S182, presenilin-1, gamma-secretase
Size :
200 μL
Price (USD) :
501 USD
Reactivity :
Human
Clonality :
Monoclonal
Host :
Mouse
Conjugate/Tag/Label :
PUREAF
Immunogen :
BioLegend's mouse anti-Presenilin 1 was raised against a portion of the n-terminal region of Presenilin 1 (RRSLGHPEP).
Application Notes :
This antibody is against the N-terminus of Presenilin 1 and detects the N-terminal fragment (NTF) generated from the proteolysis of the full-length protein (52kD).;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA