Purified (azide-free) anti-Aph-1a, 245-265 (C terminus) | BioLegend 823101 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

Purified (azide-free) anti-Aph-1a, 245-265 (C terminus)

catalog :

823101

quantity :

100 μL

price :

448 USD

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

Poly18231

reactivity :

human, mouse, rat

application :

western blot, immunocytochemistry

more info or order :

BioLegend product webpage

citations: 4

Published Application/Species/Sample/Dilution	Reference
western blot; mouse; loading ...; fig 2a	Liu L, Ding L, Rovere M, Wolfe M, Selkoe D. A cellular complex of BACE1 and γ-secretase sequentially generates Aβ from its full-length precursor. J Cell Biol. 2019;218:644-663 pubmed publisher
western blot; rat; fig 8a	Kuzuya A, Zoltowska K, Post K, Arimon M, Li X, Svirsky S, et al. Identification of the novel activity-driven interaction between synaptotagmin 1 and presenilin 1 links calcium, synapse, and amyloid beta. BMC Biol. 2016;14:25 pubmed publisher
	Sah M, Shore A, Petri S, Kanber A, Yang M, Weston M, et al. Altered excitatory transmission onto hippocampal interneurons in the IQSEC2 mouse model of X-linked neurodevelopmental disease. Neurobiol Dis. 2020;137:104758 pubmed publisher
	Lu J, Cui J, Li X, Wang X, Zhou Y, Yang W, et al. An Anti-Parkinson's Disease Drug via Targeting Adenosine A2A Receptor Enhances Amyloid-? Generation and ?-Secretase Activity. PLoS ONE. 2016;11:e0166415 pubmed publisher

product information

Antigen :

Aph-1a 245-265

Apps. Abbrev. :

WB, ICC

Cat # :

823101

Clone :

Poly18231

Item :

Purified (azide-free) anti-Aph-1a, 245-265 (C terminus)

Isotype :

Rabbit Polyclonal IgG

Other Names :

Gamma-secretase subunit APH-1A, aph-1alpha, presenilin-stabilization factor, CGI-78, anterior pharynx defective 1 homolog A, presenilin-stabilization factor

Size :

100 μL

Price (USD) :

448 USD

Reactivity :

Human

Clonality :

Polyclonal

Host :

Rabbit

Conjugate/Tag/Label :

PUREAF

Immunogen :

The antibody Aph-1a, 245-265 (Poly18231) was raised against the human Aph-1aL/C-terminal region and recognizes the sequence CRRQEDSRVMVYSALRIPPED of human Aph-1aL.

Application Notes :

This antibody is effective in immunoblotting (WB).*Expected MW: 29 kDWB Positive Control: Human Brain lysateBioLegend also offers Poly18232 (823201) which recognizes residues 92-115 of the Aph-1aL/ S Loop.This product may contain other non-IgG subtypes.;

more info or order :

BioLegend product webpage