Purified anti-Presenilin 2 | BioLegend 814203 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

Purified anti-Presenilin 2

catalog :

814203

quantity :

25 μg

price :

112 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

PS2

reactivity :

human

application :

western blot

more info or order :

BioLegend product webpage

citations: 1

Reference
Eccles M, Main N, Carlessi R, Armstrong A, Sabale M, Roberts Mok B, et al. Quantitative comparison of presenilin protein expression reveals greater activity of PS2-γ-secretase. FASEB J. 2024;38:e23396 pubmed publisher

product information

Antigen :

Presenilin 2

Apps. Abbrev. :

Cat # :

814203

Clone :

PS2

Item :

Purified anti-Presenilin 2

Isotype :

Mouse IgG1, κ

Other Names :

Presenilin-2, AD5, E5-1, PS-2, AD3LP, STM-2, gamma-secretase, PSEN2, PS2

Size :

25 μg

Price (USD) :

112 USD

Reactivity :

Human

Clonality :

Monoclonal

Host :

Mouse

Conjugate/Tag/Label :

PURE

Immunogen :

This monoclonal antibody was raised using a GST-fusion containing the complete N-terminal fragment of human Presenilin 2 (residues 1-87).

Application Notes :

Cell type: SH-SY5Y neuroblastoma cells. Presenilin 2 is proteolytically cleaved to generate two polypeptides. The full-length PS2 protein (about 55 kD) is cleaved to a about 35 kD N-terminal fragment and about 20 kD C-terminal fragment. The predominant species observed in cultured mammalian cells and in the brain is the processed fragment of about 35 kD. This antibody recognizes the full length and the about 35 kD cleavage fragment.;Primary antibody incubation period for WB: overnight at 4°C .;

more info or order :

BioLegend product webpage