| Published Application/Species/Sample/Dilution | Reference |
|---|
- western blot; human; 1:1000; loading ...; fig 1c
| Marino M, Zhou L, Rincon M, Callaerts Vegh Z, Verhaert J, Wahis J, et al. AAV-mediated delivery of an anti-BACE1 VHH alleviates pathology in an Alzheimer's disease model. EMBO Mol Med. 2022;14:e09824 pubmed publisher |
- western blot; human; loading ...; fig 1r
| Wang C, Najm R, Xu Q, Jeong D, Walker D, Balestra M, et al. Gain of toxic apolipoprotein E4 effects in human iPSC-derived neurons is ameliorated by a small-molecule structure corrector. Nat Med. 2018;24:647-657 pubmed publisher |
- western blot; human; loading ...; fig 8a
| Ruan C, Liu J, Yang M, Saadipour K, Zeng Y, Liao H, et al. Sortilin inhibits amyloid pathology by regulating non-specific degradation of APP. Exp Neurol. 2018;299:75-85 pubmed publisher |
- western blot; mouse; 1:1000; loading ...; fig 4d
| Griñan Ferré C, Sarroca S, Ivanova A, Puigoriol Illamola D, Aguado F, Camins A, et al. Epigenetic mechanisms underlying cognitive impairment and Alzheimer disease hallmarks in 5XFAD mice. Aging (Albany NY). 2016;8:664-84 pubmed publisher |
| Wang X, Shi Q, Pradhan A, Ziegon L, Schlegel M, Rammes G. Beta-Site Amyloid Precursor Protein-Cleaving Enzyme Inhibition Partly Restores Sevoflurane-Induced Deficits on Synaptic Plasticity and Spine Loss. Int J Mol Sci. 2022;23: pubmed publisher |
| Zheng Q, Song B, Li G, Cai F, Wu M, Zhao Y, et al. USP25 inhibition ameliorates Alzheimer's pathology through the regulation of APP processing and Aβ generation. J Clin Invest. 2022;132: pubmed publisher |
| Zhong B, Zhou G, Song L, Wen Q, Deng X, Ma Y, et al. TUFM is involved in Alzheimer's disease-like pathologies that are associated with ROS. FASEB J. 2021;35:e21445 pubmed publisher |
| Li K, Xiang X, Song L, Chen J, Luo B, Wen Q, et al. Mitochondrial TXN2 attenuates amyloidogenesis via selective inhibition of BACE1 expression. J Neurochem. 2021;157:1351-1365 pubmed publisher |
| Tambini M, Norris K, D ADAMIO L. Opposite changes in APP processing and human Aβ levels in rats carrying either a protective or a pathogenic APP mutation. elife. 2020;9: pubmed publisher |
| Wu Z, Palanimuthu D, Braidy N, Salikin N, Egan S, Huang M, et al. Novel multifunctional iron chelators of the aroyl nicotinoyl hydrazone class that markedly enhance cellular NAD+ /NADH ratios. Br J Pharmacol. 2020;177:1967-1987 pubmed publisher |
| Xiang J, Zhang W, Cai X, Cai M, Yu Z, Yang F, et al. DNA Aptamers Targeting BACE1 Reduce Amyloid Levels and Rescue Neuronal Deficiency in Cultured Cells. Mol Ther Nucleic Acids. 2019;16:302-312 pubmed publisher |
| Wang W, Hou T, Jia L, Wu Q, Quan M, Jia J. Toxic amyloid-β oligomers induced self-replication in astrocytes triggering neuronal injury. EBioMedicine. 2019;42:174-187 pubmed publisher |
| Tsang J, Lee M, Chan T, Li J, Ni Y, Shao Y, et al. Proteolytic cleavage of amyloid precursor protein by ADAM10 mediates proliferation and migration in breast cancer. EBioMedicine. 2018;38:89-99 pubmed publisher |
| Marwarha G, Schommer J, Lund J, Schommer T, Ghribi O. Palmitate-induced C/EBP homologous protein activation leads to NF-κB-mediated increase in BACE1 activity and amyloid beta genesis. J Neurochem. 2018;144:761-779 pubmed publisher |
| Jean Louis T, Rockwell P, Figueiredo Pereira M. Prostaglandin J2 promotes O-GlcNAcylation raising APP processing by α- and β-secretases: relevance to Alzheimer's disease. Neurobiol Aging. 2018;62:130-145 pubmed publisher |
| Kotfis K, Zegan Barańska M, Szydłowski Ł, Zukowski M, Ely E. Methods of pain assessment in adult intensive care unit patients - Polish version of the CPOT (Critical Care Pain Observation Tool) and BPS (Behavioral Pain Scale). Anaesthesiol Intensive Ther. 2017;49:66-72 pubmed publisher |
| Qin X, Wang Y, Paudel H. Early Growth Response 1 (Egr-1) Is a Transcriptional Activator of ?-Secretase 1 (BACE-1) in the Brain. J Biol Chem. 2016;291:22276-22287 pubmed |
| Salta E, Sierksma A, Vanden Eynden E, De Strooper B. miR-132 loss de-represses ITPKB and aggravates amyloid and TAU pathology in Alzheimer's brain. EMBO Mol Med. 2016;8:1005-18 pubmed publisher |
| Rabinovich Toidman P, Rabinovich Nikitin I, Ezra A, Barbiro B, Fogel H, Slutsky I, et al. Mutant SOD1 Increases APP Expression and Phosphorylation in Cellular and Animal Models of ALS. PLoS ONE. 2015;10:e0143420 pubmed publisher |
| Corbett G, Gonzalez F, Pahan K. Activation of peroxisome proliferator-activated receptor α stimulates ADAM10-mediated proteolysis of APP. Proc Natl Acad Sci U S A. 2015;112:8445-50 pubmed publisher |
